• Cholesterol crystals and NLRP3 mediated inflammation in the uterine wall decidua in normal and preeclamptic pregnancies 

      Silva, Gabriela; Gierman, Lobke; Rakner, Johanne Johnsen; Stødle, Guro; Mundal, Siv Boon; Thaning, Astrid Josefin; Sporsheim, Bjørnar; Elschot, Mattijs; Collett, Karin; Bjørge, Line; Aune, Marie Hjelmseth; Thomsen, Liv Cecilie Vestrheim; Iversen, Ann-Charlotte (Journal article; Peer reviewed, 2020)
      Preeclampsia is a hypertensive and inflammatory pregnancy disorder associated with cholesterol accumulation and inflammation at the maternal-fetal interface. Preeclampsia can be complicated with fetal growth restriction ...
    • Evaluation of Ki67 expression across distinct categories of breast cancer specimens: A Population-based study of matched surgical specimens, core needle biopsies and tissue microarrays 

      Knutsvik, Gøril; Stefansson, Ingunn; Aziz, Sura Mohammed; Arnes, Jarle; Eide, Johan; Collett, Karin; Akslen, Lars A. (Peer reviewed; Journal article, 2014-11-06)
      Introduction: Tumor cell proliferation in breast cancer is strongly prognostic and may also predict response to chemotherapy. However, there is no consensus on counting areas or cut-off values for patient stratification. ...
    • Placental inflammation by HMGB1 activation of TLR4 at the syncytium 

      Tangerås, Line Haugstad; Silva, Gabriela; Stødle, Guro; Gierman, Lobke; Skei, Bente; Collett, Karin; Beversmark, Anne Lise; Skråstad, Ragnhild Bergene; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Iversen, Ann-Charlotte (Journal article; Peer reviewed, 2018)
      Introduction Normal pregnancy is characterized by an elevated inflammatory state involving the placenta. The placental inflammation is further increased in preeclampsia, resulting in release of harmful danger signals to ...
    • Stathmin expression associates with vascular and immune responses in aggressive breast cancer subgroups 

      Askeland, Cecilie; Wik, Elisabeth; Finne, Kenneth; Birkeland, Even; Arnes, Jarle; Collett, Karin; Knutsvik, Gøril; Krüger, Kristi; Davidsen, Benedicte; Aas, Turid; Eide, Geir Egil; Stefansson, Ingunn; Foulkes, William; Akslen, Lars A. (Journal article; Peer reviewed, 2020)
      Studies indicate that stathmin expression associates with PI3K activation in breast cancer, suggesting stathmin as a marker for targetable patient subgroups. Here we assessed stathmin in relation to tumour proliferation, ...