Blar i Bergen Open Research Archive på forfatter "Cox, Heinz Jürgen"
-
Maxquant software for ion mobility enhanced shotgun proteomics
Prianichnikov, Nikita; Koch, Heiner; Koch, Scarlet; Lubeck, Markus; Heilig, Raphael; Brehmer, Sven; Fischer, Roman; Cox, Heinz Jürgen (Journal article; Peer reviewed, 2020)Ion mobility can add a dimension to LC-MS based shotgun proteomics which has the potential to boost proteome coverage, quantification accuracy and dynamic range. Required for this is suitable software that extracts the ... -
Role for ribosome-associated quality control in sampling proteins for MHC class I-mediated antigen presentation
Trentini, Débora Broch; Pecoraro, Matteo; Tiwary, Shivani; Cox, Heinz Jürgen; Mann, Matthias; Hipp, Mark S.; Hartl, F. Ulrich (Journal article; Peer reviewed, 2020)Pathogens and tumors are detected by the immune system through the display of intracellular peptides on MHC-I complexes. These peptides are generated by the ubiquitin−proteasome system preferentially from newly synthesized ...