Browsing Bergen Open Research Archive by Author "Cox, Heinz Jürgen"

Now showing items 1-3 of 3

    • Accurate and Automated High-Coverage Identification of Chemically Cross-Linked Peptides with MaxLynx 

      Yllmaz, Şule; Busch, Florian; Nagaraj, Nagarjuna; Cox, Heinz Jürgen (Journal article; Peer reviewed, 2022)
      Cross-linking combined with mass spectrometry (XL-MS) provides a wealth of information about the three-dimensional (3D) structure of proteins and their interactions. We introduce MaxLynx, a novel computational proteomics ...

    • Maxquant software for ion mobility enhanced shotgun proteomics 

      Prianichnikov, Nikita; Koch, Heiner; Koch, Scarlet; Lubeck, Markus; Heilig, Raphael; Brehmer, Sven; Fischer, Roman; Cox, Heinz Jürgen (Journal article; Peer reviewed, 2020)
      Ion mobility can add a dimension to LC-MS based shotgun proteomics which has the potential to boost proteome coverage, quantification accuracy and dynamic range. Required for this is suitable software that extracts the ...

    • Role for ribosome-associated quality control in sampling proteins for MHC class I-mediated antigen presentation 

      Trentini, Débora Broch; Pecoraro, Matteo; Tiwary, Shivani; Cox, Heinz Jürgen; Mann, Matthias; Hipp, Mark S.; Hartl, F. Ulrich (Journal article; Peer reviewed, 2020)
      Pathogens and tumors are detected by the immune system through the display of intracellular peptides on MHC-I complexes. These peptides are generated by the ubiquitin−proteasome system preferentially from newly synthesized ...