• DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease 

      Lee, Jin H.; McDonald, Merry-Lynn N.; Cho, Michael H.; Wan, Emily S.; Castaldi, Peter J.; Hunninghake, Gary M.; Marchetti, Nathaniel; Lynch, David A.; Crapo, James D.; Lomas, David A.; Coxson, Harvey O.; Bakke, Per; Silverman, Edwin K.; Hersh, Craig P. (Peer reviewed; Journal article, 2014-08-20)
      Background: Chronic obstructive pulmonary disease (COPD) is characterized by expiratory flow limitation, causing air trapping and lung hyperinflation. Hyperinflation leads to reduced exercise tolerance and poor quality of ...
    • Markers of disease activity in COPD: an 8-year mortality study in the ECLIPSE cohort 

      Celli, Bartolome; Locantore, Nicholas; Yates, Julie C.; Bakke, Per S.; Calverley, Peter M.A.; Crim, Courtney; Coxson, Harvey O.; Lomas, David A.; MacNee, William; Miller, Bruce E.; Mullerova, Hana; Rennard, Stephen I.; Silverman, Edwin K.; Wouters, Emiel F.; Tal-Singer, Ruth; Agusti, Alvar; Vestbo, Jørgen (Journal article; Peer reviewed, 2021)
      Rationale There are no validated measures of disease activity in COPD. Since “active” disease is expected to have worse outcomes (e.g. mortality), we explored potential markers of disease activity in patients enrolled in ...