• The association of PTSD symptom severity with amygdala nuclei volumes in traumatized youths 

      Ousdal, Olga Therese; Milde, Anne Marita; Hafstad, Gertrud Sofie; Hodneland, Erlend; Dyb, Grete; Craven, Alexander R.; Melinder, Annika Maria D; Endestad, Tor; Hugdahl, Kenneth (Journal article; Peer reviewed, 2020)
      The amygdala is a core component in neurobiological models of stress and stress-related pathologies, including post-traumatic stress disorder (PTSD). While numerous studies have reported increased amygdala activity following ...
    • Big GABA II: Water-referenced edited MR spectroscopy at 25 research sites 

      Mikkelsen, Mark; Rimbault, Daniel L.; Barker, Peter B.; Bhattacharyya, Pallab K.; Brix, Maiken Kirkegaard; Buur, Pieter F.; Cecil, Kim M.; Chan, Kimberly L.; Chen, David Y.-T.; Craven, Alexander R.; Cuypers, Koen; Dacko, Michael; Duncan, Niall W.; Dydak, Ulrike; Edmondson, David A.; Ende, Gabriele; Ersland, Lars; Forbes, Megan A.; Gao, Fei; Greenhouse, Ian; Harris, Ashley D.; He, Naying; Heba, Stefanie; Hoggard, Nigel; Hsu, Tun-Wei; Jansen, Jacobus F.A.; Kangarlu, Alayar; Lange, Thomas; Lebel, R. Marc; Li, Yan; Lin, Chien-Yuan E.; Liou, Jy-Kang; Lirng, Jiing-Feng; Liu, Feng; Long, Joanna R.; Ma, Ruoyun; Maes, Celine; Moreno-Ortega, Marta; Murray, Scott O.; Noah, Sean; Noeske, Ralph; Noseworthy, Michael D.; Oeltzschner, Georg; Porges, Eric C.; Prisciandaro, James J.; Puts, Nicolaas A.J.; Roberts, Timothy P.L.; Sack, Markus; Sailasuta, Napapon; Saleh, Muhammad G.; Schallmo, Michael-Paul; Simard, Nicholas; Stoffers, Diederick; Swinnen, Stephan P.; Tegenthoff, Martin; Truong, Peter; Wang, Guangbin; Wilkinson, Iain D.; Wittsack, Hans-Jörg; Woods, Adam J.; Xu, Hongmin; Yan, Fuhua; Zhang, Chencheng; Zipunnikov, Vadim; Zöllner, Helge J.; Edden, Richard A.E. (Peer reviewed; Journal article, 2019)
      Accurate and reliable quantification of brain metabolites measured in vivo using 1H magnetic resonance spectroscopy (MRS) is a topic of continued interest. Aside from differences in the basic approach to quantification, ...
    • Brain age prediction reveals aberrant brain white matter in schizophrenia and bipolar disorder: A multi-sample diffusion tensor imaging study 

      Tønnesen, Siren; Kaufmann, Tobias; de Lange, Ann-Marie Glasø; Richard, Geneviève; Nhat Trung, Doan; Alnæs, Dag; van der Meer, Dennis; Rokicki, Jaroslav; Moberget, Torgeir; Maximov, Ivan; Agartz, Ingrid; Aminoff, Sofie Ragnhild; Beck, Dani; Barch, Deanna M.; Beresniewicz, Justyna; Cervenka, Simon; Fatouros-Bergman, Helena; Craven, Alexander R.; Flyckt, Lena; Gurholt, Tiril Pedersen; Haukvik, Unn Kristin H.; Hugdahl, Kenneth; Johnsen, Erik; Jönsson, Erik Gunnar; Schizophrenia Project (KaSP), Karolinska; Kolskår, Knut-Kristian; Kroken, Rune Andreas; Lagerberg, Trine Vik; Løberg, Else-Marie; Nordvik, Jan Egil; Sanders, Anne-Marthe; Ulrichsen, Kristine Moe; Andreassen, Ole Andreas; Westlye, Lars Tjelta (Journal article; Peer reviewed, 2020)
      Background Schizophrenia (SZ) and bipolar disorder (BD) share substantial neurodevelopmental components affecting brain maturation and architecture. This necessitates a dynamic lifespan perspective in which brain aberrations ...
    • “Brain MR spectroscopy in autism spectrum disorder—the GABA excitatory/inhibitory imbalance theory revisited” 

      Brix, Maiken Kirkegaard; Ersland, Lars; Hugdahl, Kenneth; Grüner, Renate; Posserud, Maj-Britt; Hammar, Åse; Craven, Alexander R.; Noeske, Ralph; Evans, C. John; Walker, Hanne B.; Midtvedt, Tore; Beyer, Mona K. (Peer reviewed; Journal article, 2015-06-22)
      Magnetic resonance spectroscopy (MRS) from voxels placed in the left anterior cingulate cortex (ACC) was measured from 14 boys with Autism Spectrum Disorder (ASD) and 24 gender and age-matched typically developing (TD) ...
    • Glutamatergic modulation of auditory cortex connectivity with attentional brain networks in unpredictable perceptual environment 

      Kompus, Kristiina; Volehaugen, Vegard; Craven, Alexander R.; Specht, Karsten (Journal article; Peer reviewed, 2020)
      In a stable environment the brain can minimize processing required for sensory input by forming a predictive model of the surrounding world and suppressing neural response to predicted stimuli. Unpredicted stimuli lead to ...
    • Impact of glutamate levels on neuronal response and cognitive abilities in schizophrenia 

      Falkenberg, Liv Eggset; Westerhausen, René; Craven, Alexander R.; Kroken, Rune A.; Løberg, Else-Marie; Specht, Karsten; Hugdahl, Kenneth (Peer reviewed; Journal article, 2014-04-02)
      Schizophrenia is characterized by impaired cognitive functioning, and brain regions involved in cognitive control processes show marked glutamatergic abnormalities. However, it is presently unclear whether aberrant neuronal ...
    • Multi-vendor standardized sequence for edited magnetic resonance spectroscopy 

      Saleh, Muhammad G.; Rimbault, Daniel; Mikkelsen, Mark; Oeltzschner, Georg; Wang, Anna M; Jiang, Dengrong; Alhamud, Ali; Near, Jamie; Schär, Michael; Noeske, Ralph; Murdoch, James B; Ersland, Lars; Craven, Alexander R.; Dwyer, Gerard Eric; Grüner, Renate; Pan, Li; Ahn, Sinyeob; Edden, Richard A.E. (Peer reviewed; Journal article, 2019)
      Spectral editing allows direct measurement of low-concentration metabolites, such as GABA, glutathione (GSH) and lactate (Lac), relevant for understanding brain (patho)physiology. The most widely used spectral editing ...
    • No Effects of Anodal tDCS on Local GABA and Glx Levels in the Left Posterior Superior Temporal Gyrus 

      Dwyer, Gerard Eric; Craven, Alexander R.; Hirnstein, Marco; Kompus, Kristiina; Assmus, Jörg; Ersland, Lars; Hugdahl, Kenneth; Grüner, Renate (Peer reviewed; Journal article, 2019-01-08)
      A number of studies investigating the biological effects of transcranial direct current stimulation (tDCS) using magnetic resonance spectroscopy (MRS) have found that it may affect local levels of γ-aminobutyric acid (GABA), ...