Blar i Bergen Open Research Archive på forfatter "Cupul-Uicab, Lea A"
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450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy
Joubert, Bonnie R.; Håberg, Siri Eldevik; Nilsen, Roy Miodini; Wang, Xuting; Vollset, Stein Emil; Murphy, Susan K; Huang, Zhiqing; Hoyo, Cathrine; Midttun, Øivind; Cupul-Uicab, Lea A; Ueland, Per Magne; Wu, Michael C; Nystad, Wenche; Bell, Douglas A; Peddada, Shyamal D; London, Stephanie J (Peer reviewed; Journal article, 2012-10)Background: Epigenetic modifications, such as DNA methylation, due to in utero exposures may play a critical role in early programming for childhood and adult illness. Maternal smoking is a major risk factor for multiple ... -
Exposure to Tobacco Smoke in Utero and Subsequent Plasma Lipids, ApoB, and CRP among Adult Women in the MoBa Cohort
Cupul-Uicab, Lea A; Skjaerven, Rolv; Haug, Kjell; Travlos, GS; Wilson, RE; Eggesbø, Merete Åse; Hoppin, Jane A; Whitworth, KW; Longnecker, MP (Peer reviewed; Journal article, 2012-11)Background: Recent findings suggest that maternal smoking during pregnancy may play a role in the development of metabolic alterations in offspring during childhood. However, whether such exposure increases the risk of ... -
In utero exposure to maternal tobacco smoke and subsequent obesity, hypertension, and gestational diabetes among women in the MoBa Cohort
Cupul-Uicab, Lea A; Skjaerven, Rolv; Haug, Kjell; Melve, Kari Klungsøyr; Engel, Stephani M; Longnecker, Matthew P (Peer reviewed; Journal article, 2012)Background: Environmental factors influencing the developmental origins of health and disease need to be identified and investigated. In utero exposure to tobacco smoke has been associated with obesity and a small increase ...