• Embryonic Stem Cells Can Generate Oral Epithelia under Matrix Instruction 

      Das, Ridhima; Harper, Lisa; Kitajima, Kayoko; Osman, Tarig Al-Hadi; Cimpan, Mihaela-Roxana; Johannessen, Anne Christine; Suliman, Salwa; Mackenzie, Ian C.; Costea, Daniela Elena (Journal article; Peer reviewed, 2023)
      We aimed to investigate whether molecular clues from the extracellular matrix (ECM) can induce oral epithelial differentiation of pluripotent stem cells. Mouse embryonic stem cells (ESC) of the feeder-independent cell line ...
    • Granulocyte macrophage-colony stimulating factor and keratinocyte growth factor control of early stages of differentiation of oral epithelium 

      Das, Ridhima; Virlan, Maria Justina Roxana; Xenaki, Victoria; Kulasekara, Keerthi Kumara; Lukandu, Ochiba Mohammed; Neppelberg, Evelyn; Vintermyr, Olav Karsten; Johannessen, Anne Christine; Calenic, Bogdan; Costea, Daniela Elena (Journal article; Peer reviewed, 2022)
      Oral epithelial differentiation is known to be directed by underlying fibroblasts, but the responsible factor(s) have not been identified. We aimed here to identify fibroblast-derived factors responsible for oral epithelial ...
    • Isolation and characterization of cells derived from human epithelial rests of Malassez 

      Kitajima, Kayoko; Das, Ridhima; Liang, Xiao; Neppelberg, Evelyn; Johannessen, Anne Christine; Costea, Daniela Elena; Igarashi, Masaru (Journal article; Peer reviewed, 2019)
      The epithelial rests of Malassez (ERMs) might represent a valuable source of oral epithelial cells with stem cell properties. The purpose of this study was to isolate and characterize cells derived from human ERM, and ...
    • Novel Methods and Sources for Regeneration of Oral Mucosa 

      Das, Ridhima (Doctoral thesis, 2022-06-16)
      Background: Common clinical approaches for replacing damaged oral mucosa are represented by autologous skin grafts which have numerous shortcomings and pose serious post-surgical morbidity. Cultured oral mucosal sheets ...