• Association between visceral, cardiac and sensorimotor polyneuropathies in diabetes mellitus 

      Søfteland, Eirik; Brock, Christina; Frøkjær, Jens B.; Brøgger, Jan C.; Madácsy, László; Gilja, Odd Helge; Arendt-Nielsen, Lars; Simrén, Magnus; Drewes, Asbjørn M.; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2014)
      Aims: Gastrointestinal complaints are common in diabetes mellitus. However, its association to peripheral sensorimotor and autonomic neuropathies is not well investigated. The aim was to assess skin, muscle, bone and ...
    • Automated spectrophotometric bicarbonate analysis in duodenal juice compared to the back titration method 

      Erchinger, Friedemann Georg; Engjom, Trond; Gudbrandsen, Oddrun Anita; Tjora, Erling; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2016-02-03)
      Objectives We have recently evaluated a short endoscopic secretin test for exocrine pancreatic function. Bicarbonate concentration in duodenal juice is an important parameter in this test. Measurement of bicarbonate by ...
    • Comparing radiopaque markers and 13C-labelled breath test in diabetic gastroparesis diagnostics 

      Sangnes, Dag André; Softeland, Eirik; Teigland, Tonje; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2019)
      Purpose: Determining gastric emptying is mandatory in the diagnosis of diabetic gastroparesis. Several methods of investigation exist, but none has proven reliable, inexpensive and accessible. In this study, we aimed to ...
    • Diagnostic accuracy of a short endoscopic secretin test in patients with cystic fibrosis 

      Engjom, Trond; Erchinger, Friedemann Georg; Lærum, Birger Norderud; Tjora, Erling; Aksnes, Lage; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2015-02-16)
      Objective: Short endoscopic secretin tests for exocrine pancreatic function are not properly evaluated in cystic fibrosis (CF). Methods: Patients with CF and healthy controls (HCs) underwent endoscopic collection of duodenal ...
    • Diagnostic accuracy of transabdominal ultrasound in chronic pancreatitis 

      Engjom, Trond; Sangnes, Dag André; Havre, Roald Flesland; Erchinger, Friedemann Georg; Pham, Khanh Do-Cong; Haldorsen, Ingfrid S.; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2017-04)
      The performance of transabdominal ultrasound (US) in chronic pancreatitis (CP) following the advances in US technology made during recent decades has not been explored. Our aim in this prospective study was to evaluate the ...
    • Fecal fat analyses in chronic pancreatitis importance of fat ingestion before stool collection 

      Erchinger, Friedemann Georg; Engjom, Trond; Jurmy, Palwasha; Tjora, Erling; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2017-01-17)
      Objective: Quantitative determination of fecal fat still is the gold standard for measuring malabsorption. We evaluated the importance of standardized food intake before and under the collection of feces. Material and ...
    • A human clinical trial using ultrasound and microbubbles to enhance gemcitabine treatment of inoperable pancreatic cancer 

      Dimcevski, Georg Gjorgji; Kotopoulis, Spiros; Bjånes, Tormod Karlsen; Hoem, Dag; Schjøtt, Jan; Gjertsen, Bjørn Tore; Biermann, Martin; Molven, Anders; Sorbye, Halfdan; McCormack, Emmet; Postema, Michiel; Gilja, Odd Helge (Peer reviewed; Journal article, 2016-12)
      Background: The primary aim of our study was to evaluate the safety and potential toxicity of gemcitabine combined with microbubbles under sonication in inoperable pancreatic cancer patients. The secondary aim was to ...
    • Prolonged intestinal transit and diarrhea in patients with an activating GUCY2C mutation 

      Volkmann, Hilde Løland Von; Brønstad, Ingeborg; Gilja, Odd Helge; Tronstad, Rune Rose; Sangnes, Dag André; Nortvedt, Ragnar; Hausken, Trygve; Dimcevski, Georg Gjorgji; Fiskerstrand, Torunn; Nylund, Kim (Peer reviewed; Journal article, 2017)
      Introduction: Increased intestinal hydration by activation of the epithelial enzyme linked receptor guanylate cyclase C (GC-C) is a pharmacological principle for treating constipation. Activating mutations in the GUCY2C ...
    • Rectal Sensitivity in Diabetes Patients with Symptoms of Gastroparesis 

      Søfteland, Eirik; Brock, Christina; Frøkjær, Jens B.; Simrén, Magnus; Drewes, Asbjørn M.; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2014-07-22)
      In a clinical setting, diabetic autonomic complications (cardiac, gastrointestinal, urogenital, etc.) are often handled as separate entities. We investigated rectal sensitivity to heat, mechanical distension, and electrical ...
    • Secretin-stimulated ultrasound estimation of pancreatic secretion in cystic fibrosis validated by magnetic resonance imaging 

      Engjom, Trond; Tjora, Erling; Wathle, Gaute Kjellevold; Erchinger, Friedemann Georg; Lærum, Birger Norderud; Gilja, Odd Helge; Haldorsen, Ingfrid S.; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2018-04)
      Objectives: Secretin-stimulated magnetic resonance imaging (s-MRI) is the best validated radiological modality assessing pancreatic secretion. The purpose of this study was to compare volume output measures from ...
    • Ultrasound echo-intensity predicts severe Pancreatic affection in cystic fibrosis patients 

      Engjom, Trond; Erchinger, Friedemann Georg; Lærum, Birger Norderud; Tjora, Erling; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2015-03-24)
      Background: Pancreatic destruction affects the majority of patients with cystic fibrosis. We aimed to relate ultrasound findings to exocrine pancreatic function and cystic fibrosis genotype. Methods: Patients with cystic ...
    • Wireless motility capsule compared with scintigraphy in the assessment of diabetic gastroparesis 

      Sangnes, Dag André; Søfteland, Eirik; Bekkelund, Mattis; Frey, Jakub; Biermann, Martin; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2019-12-30)
      Background: Gastroparesis is a potentially severe late complication of diabetes mellitus. Today, delayed gastric emptying (GE) is mandatory for establishing the diagnosis. In this study, we compared wireless motility capsule ...