Browsing Bergen Open Research Archive by Author "Dolan, David William Peter"

Now showing items 1-6 of 6

    • Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner 

      Lagnado, Anthony; Leslie, Jack; Ruchaud-Sparagano, Marie-Helene; Victorelli, Stella; Hirsova, Petra; Ogrodnik, Mikolaj; Collins, Amy L; Vizioli, Maria Grazia; Habiballa, Leena; Saretzki, Gabriele; Evans, Shane A; Salmonowicz, Hanna; Hruby, Adam; Geh, Daniel; Pavelko, Kevin D; Dolan, David William Peter; Reeves, Helen L; Grellscheid, Sushma Nagaraja; Wilson, Colin H; Pandanaboyana, Sanjay; Doolittle, Madison; von Zglinicki, Thomas; Oakley, Fiona; Gallage, Suchira; Wilson, Caroline L; Birch, Jodie; Carroll, Bernadette; Chapman, James; Heikenwalder, Mathias; Neretti, Nicola; Khosla, Sundeep; Masuda, Claudio Akio; Tchkonia, Tamar; Kirkland, James L; Jurk, Diana; Mann, Derek A.; Passos, João F (Journal article; Peer reviewed, 2021)
      Cellular senescence is characterized by an irreversible cell cycle arrest as well as a pro-inflammatory phenotype, thought to contribute to aging and age-related diseases. Neutrophils have essential roles in inflammatory ...

    • NvPOU4/Brain3 Functions as a Terminal Selector Gene in the Nervous System of the Cnidarian Nematostella vectensis 

      Tourniere, Oceane Barbara; Dolan, David William Peter; Richards, Gemma Sian; Sunagar, Kartik; Columbus-Shenkar, Yaara Y; Moran, Yehu; Rentzsch, Fabian (Journal article; Peer reviewed, 2020-03)
      Terminal selectors are transcription factors that control the morphological, physiological, and molecular features that characterize distinct cell types. Here, we show that, in the sea anemone Nematostella vectensis, NvPOU4 ...

    • Photoreception and transcriptomic response to light during early development of a teleost with a life cycle tightly controlled by seasonal changes in photoperiod 

      Eilertsen, Mariann; Dolan, David William Peter; Bolton, Charlotte M.; Karlsen, Rita; Davies, Wayne I.L.; Edvardsen, Rolf Brudvik; Furmanek, Tomasz; Sveier, Harald; Migaud, Herve; Helvik, Jon Vidar (Journal article; Peer reviewed, 2022)
      Light cues vary along the axis of periodicity, intensity and spectrum and perception of light is dependent on the photoreceptive capacity encoded within the genome and the opsins expressed. A global approach was taken to ...

    • Potential Transcriptional Biomarkers to Guide Glucocorticoid Replacement in Autoimmune Addison's Disease 

      Sævik, Åse Bjorvatn; Wolff, Anette Susanne Bøe; Björnsdottir, Sigridur; Simunkova, Katerina; Hynne, Martha Schei; Dolan, David William Peter; Bratland, Eirik; Knappskog, Per M; Methlie, Paal; Carlsen, Siri; Isaksson, Magnus; Bensing, Sophie; Kämpe, Olof; Husebye, Eystein S; Løvås, Kristian; Øksnes, Marianne (Journal article; Peer reviewed, 2021)
      Background No reliable biomarkers exist to guide glucocorticoid (GC) replacement treatment in autoimmune Addison’s disease (AAD), leading to overtreatment with alarming and persistent side effects or undertreatment, which ...

    • Systemic interferon type I and B cell responses are impaired in autoimmune polyendocrine syndrome type 1 

      Oftedal, Bergithe Eikeland; Delaleu, Nicolas; Dolan, David William Peter; Meager, Anthony; Husebye, Eystein Sverre; Wolff, Anette Susanne Bøe (Journal article; Peer reviewed, 2023)
      Autoimmune polyendocrine syndrome type I (APS-1) is caused by mutations in the autoimmune regulator (AIRE) gene and characterised clinically by multiple autoimmune manifestations and serologically by autoantibodies against ...

    • Transcriptome-wide analyses of early immune responses in lumpfish leukocytes upon stimulation with poly(I:C) 

      Sadashiva Rao, Shreesha; Lunde, Harald Sæbø; Dolan, David William Peter; Fond, Amanda Kästel Sandal; Petersen, Kjell; Haugland, Gyri Teien (Journal article; Peer reviewed, 2023)
      Background: Both bacterial and viral diseases are a major threat to farmed fish. As the antiviral immune mechanisms in lumpfish (Cyclopterus lumpus L.) are poorly understood, lumpfish leukocytes were stimulated with ...