Browsing Bergen Open Research Archive by Author "Dongre, Harsh Nitin"
Now showing items 1-7 of 7
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Characterization of immune cell infiltrate in tumor stroma and epithelial compartments in oral squamous cell carcinomas of Sudanese patients
Mohamed, Nuha Mohamed Gaafar; Osman, Tarig Al-Hadi; Ahmed, Israa A.H.; Elsheikh, Mariam; Dongre, Harsh Nitin; Jacobsen, Martha Rolland; Mohamed, Nazar; Fromreide, Siren; Suleiman, Ahmed Mohamed; Johannessen, Anne Christine; Nginamau, Elisabeth Sivy; Costea, Daniela Elena (Journal article; Peer reviewed, 2021)Background Tumor immune infiltrate has been explored in oral squamous cell carcinoma (OSCC), but studies on simultaneous characterization of multiple immune cell subtypes separately in stromal and intraepithelial tumor ... -
Ectopic Bone Tissue Engineering in Mice Using Human Gingiva or Bone Marrow-Derived Stromal/Progenitor Cells in Scaffold-Hydrogel Constructs
Shanbhag, Siddharth; Kampleitner, Carina; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Yassin, Mohammed Ahmed Alamin Yousif; Dongre, Harsh Nitin; Costea, Daniela Elena; Tangl, Stefan; Stavropoulos, Andreas; Bolstad, Anne Isine; Suliman, Salwa; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2021-11-30)Three-dimensional (3D) spheroid culture can promote the osteogenic differentiation and bone regeneration capacity of mesenchymal stromal cells (MSC). Gingiva-derived progenitor cells (GPC) represent a less invasive alternative ... -
Epithelial PD-L1 expression at tumor front predicts overall survival in a cohort of oral squamous cell carcinomas from Sudan
Mohamed, Nuha Mohamed Gaafar; Osman, Tarig Al-Hadi; Elsheikh, Mariam; Alhaj Ahmed, Israa Abdul Rhman Hassaballah; Dongre, Harsh Nitin; Fromreide, Siren; Suleiman, Ahmed M.; Johannessen, Anne Christine; Nginamau, Elisabeth Sivy; Costea, Daniela Elena (Journal article; Peer reviewed, 2022)Background We recently described the tumor immune microenvironment (TIME) in oral squamous cell carcinomas (OSCC) from Sudan by assessing the core of the lesions. However, the invasive tumor front (ITF) is the most active ... -
Human gingival epithelial cells stimulate proliferation, migration, and tube formation of lymphatic endothelial cells in vitro
Indrelid, Stine Hufthammer; Dongre, Harsh Nitin; Nunes, Ivana Pereira; Virtej, Anca; Bletsa, Athanasia; Berggreen, Ellen (Journal article; Peer reviewed, 2023)Objective The aim of this study was to investigate the response of gingival epithelial cells to microbial and inflammatory signals. Background The gingival epithelial barrier provides the first line of defense and ... -
MicroRNA-138 abates fibroblast motility with effect on invasion of adjacent cancer cells
Rajthala, Saroj; Parajuli, Himalaya; Dongre, Harsh Nitin; Ljøkjel, Borghild; Hoven, Kristin Marie; Kvalheim, Arild; Lybak, Stein; Neppelberg, Evelyn; Sapkota, Dipak; Johannessen, Anne Christine; Costea, Daniela Elena (Journal article; Peer reviewed, 2022-03-17)Background: Recent studies have shown aberrant expression of micro-RNAs in cancer-associated fibroblasts (CAFs). This study aimed to investigate miR-138 dysregulation in CAFs in oral squamous cell carcinoma (OSCC) and its ... -
The TP53 Codon 72 Arginine Polymorphism Is Found with Increased TP53 Somatic Mutations in HPV(−) and in an Increased Percentage among HPV(+) Norwegian HNSCC Patients
Moe, Svein Erik Emblem; Erland, Fredrik Atteraas; Fromreide, Siren; Lybak, Stein; Brydøy, Marianne; Dongre, Harsh Nitin; Manueldas, Sophia; Costea, Daniela Elena; Vintermyr, Olav Karsten; Aarstad, Hans Jørgen (Journal article; Peer reviewed, 2023-06-26)Background: Somatic TP53 mutations are frequent in head and neck squamous cell carcinoma (HNSCC) and are important pathogenic factors. Objective: To study TP53 mutations relative to the presence of human papillomavirus ... -
TP53 mutation and human papilloma virus status as independent prognostic factors in a Norwegian cohort of vulva squamous cell carcinoma
Dongre, Harsh Nitin; Elnour, Rammah; Tornaas, Stian; Fromreide, Siren; Thomsen, Liv Cecilie Vestrheim; Kolseth, Ingrid Moss; Nginamau, Elisabeth Sivy; Johannessen, Anne Christine; Vintermyr, Olav Karsten; Costea, Daniela Elena; Bjørge, Line (Journal article; Peer reviewed, 2024)Introduction: Vulva squamous cell carcinoma (VSCC) develops through two separate molecular pathways—one involving high-risk human papilloma virus infection (HPV-associated), and the other without HPV infection (HPV-independent) ...