• Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer 

      Shen, Hui; Fridley, BL; Song, HL; Lawrenson, K; Cunningham, JM; Ramus, SJ; Cicek, MS; Tyrer, J; Stram, D; Larson, MC; Kobel, M; Ziogas, A; Zheng, W; Yang, HP; Wu, AH; Wozniak, EL; Woo, YL; Winterhoff, B; Wik, Elisabeth; Whittemore, AS; Wentzensen, N; Weber, RP; Vitonis, AF; Vincent, D; Vierkant, RA; Vergote, I; Van Den Berg, D; Van Altena, AM; Tworoger, SS; Thompson, PJ; Tessier, DC; Terry, KL; Teo, SH; Templeman, C; Stram, DO; Southey, MC; Sieh, W; Siddiqui, N; Shvetsov, YB; Shu, XO; Shridhar, V; Wang-Gohrke, S; Severi, G; Schwaab, I; Salvesen, Helga Birgitte; Rzepecka, IK; Runnebaum, IB; Rossing, MA; Rodriguez-Rodriguez, L; Risch, HA; Renner, SP; Poole, EM; Pike, MC; Phelan, CM; Pelttari, LM; Pejovic, T; Paul, J; Orlow, I; Omar, SZ; Olson, SH; Odunsi, K; Nickels, S; Nevanlinna, H; Ness, RB; Narod, SA; Nakanishi, T; Moysich, KB; Monteiro, ANA; Moes-Sosnowska, J; Modugno, F; Menon, U; McLaughlin, JR; McGuire, V; Matsuo, K; Adenan, NAM; Massuger, LFAG; Lurie, G; Lundvall, L; Lubinski, J; Lissowska, J; Levine, DA; Leminen, A; Lee, AW; Le, ND; Lambrechts, S; Lambrechts, D; Kupryjanczyk, J; Krakstad, Camilla; Konecny, GE; Kjaer, SK; Kiemeney, LA; Kelemen, LE; Keeney, GL; Karlan, BY; Karevan, R; Kalli, KR; Kajiyama, H; Ji, BT; Jensen, A; Jakubowska, A; Iversen, E; Hosono, S; Hogdall, CK; Hogdall, E; Hoatlin, M; Hillemanns, P; Heitz, F; Hein, R; Harter, P; Halle, Mari Kyllesø; Hall, P; Gronwald, J; Gore, M; Goodman, MT; Giles, GG; Gentry-Maharaj, A; Garcia-Closas, M; Flanagan, JM; Fasching, PA; Ekici, AB; Edwards, R; Eccles, D; Easton, DF; Durst, M; du Bois, A; Dork, T; Doherty, JA; Despierre, E; Dansonka-Mieszkowska, A; Cybulski, C; Cramer, DW; Cook, LS; Chen, XQ; Charbonneau, B; Chang-Claude, J; Campbell, I; Butzow, R; Bunker, CH; Brueggmann, D; Brown, R; Brooks-Wilson, A; Brinton, LA; Bogdanova, N; Block, MS; Benjamin, E; Beesley, J; Beckmann, MW; Bandera, EV; Baglietto, L; Bacot, F; Armasu, SM; Antonenkova, N; Anton-Culver, H; Aben, KK; Liang, D; Wu, XF; Lu, KR; Hildebrandt, MAT; Schildkraut, JM; Sellers, TA; Huntsman, D; Berchuck, A; Chenevix-Trench, G; Gayther, SA; Pharoah, PDP; Laird, PW; Goode, EL; Pearce, CL (Peer reviewed; Journal article, 2013-03-27)
      HNF1B is overexpressed in clear cell epithelial ovarian cancer, and we observed epigenetic silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this gene differentially associates with ...
    • Guidelines for follow-up of women at high risk for inherited breast cancer: Consensus statement from the Biomed 2 Demonstration programme on inherited breast cancer 

      Møller, Per; Evans, G; Vasen, H; Reis, MM; Haites, N; Anderson, E; Apold, Jaran; Hodgson, S; Eccles, D; Olsson, H; Stoppa-Llyonnet, D; et al., - (Peer reviewed; Journal article, 1999)
      Protocols for activity aiming at early diagnosis and treatment of inherited breast or breast-ovarian cancer have been reported. Available reports on outcome of such programmes are considered here. It is concluded that the ...
    • Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31 

      Permuth-Wey, Jennifer; Lawrenson, K; Shen, HC; Velkova, A; Tyrer, JP; Chen, ZH; Lin, HY; Chen, YA; Tsai, YY; Qu, XT; Ramus, SJ; Karevan, R; Lee, J; Lee, N; Larson, MC; Aben, KK; Anton-Culver, H; Antonenkova, N; Antoniou, AC; Armasu, SM; Bacot, F; Baglietto, L; Bandera, EV; Barnholtz-Sloan, J; Beckmann, MW; Birrer, MJ; Bloom, G; Bogdanova, N; Brinton, LA; Brooks-Wilson, A; Brown, R; Butzow, R; Cai, QY; Campbell, I; Chang-Claude, J; Chanock, S; Chenevix-Trench, G; Cheng, JQ; Cicek, MS; Coetzee, GA; Cook, LS; Couch, FJ; Cramer, DW; Cunningham, JM; Dansonka-Mieszkowska, A; Despierre, E; Doherty, JA; Dork, T; du Bois, A; Durst, M; Easton, DF; Eccles, D; Edwards, R; Ekici, AB; Fasching, PA; Fenstermacher, DA; Flanagan, JM; Garcia-Closas, M; Gentry-Maharaj, A; Giles, GG; Glasspool, RM; Gonzalez-Bosquet, J; Goodman, MT; Gore, M; Gorski, B; Gronwald, J; Hall, P; Halle, Mari Kyllesø; Harter, P; Heitz, F; Hillemanns, P; Hoatlin, M; Hogdall, CK; Hogdall, E; Hosono, S; Jakubowska, A; Jensen, A; Jim, H; Kalli, KR; Karlan, BY; Kaye, SB; Kelemen, LE; Kiemeney, LA; Kikkawa, F; Konecny, GE; Krakstad, Camilla; Kjaer, SK; Kupryjanczyk, J; Lambrechts, D; Lambrechts, S; Lancaster, JM; Le, ND; Leminen, A; Levine, DA; Liang, D; Lim, BK; Lin, J; Lissowska, J; Lu, KH; Lubinski, J; Lurie, G; Massuger, LFAG; Matsuo, K; McGuire, V; McLaughlin, JR; Menon, U; Modugno, F; Moysich, KB; Nakanishi, T; Narod, SA; Nedergaard, L; Ness, RB; Nevanlinna, H; Nickels, S; Noushmehr, H; Odunsi, K; Olson, SH; Orlow, I; Paul, J; Pearce, CL; Pejovic, T; Pelttari, LM; Pike, MC; Poole, EM; Raska, P; Renner, SP; Risch, HA; Rodriguez-Rodriguez, L; Rossing, MA; Rudolph, A; Runnebaum, IB; Rzepecka, IK; Salvesen, Helga Birgitte; Schwaab, I; Severi, G; Shridhar, V; Shu, XO; Shvetsov, YB; Sieh, W; Song, HL; Southey, MC; Spiewankiewicz, B; Stram, D; Sutphen, R; Teo, SH; Terry, KL; Tessier, DC; Thompson, PJ; Tworoger, SS; van Altena, AM; Vergote, I; Vierkant, RA; Vincent, D; Vitonis, AF; Wang-Gohrke, S; Weber, RP; Wentzensen, N; Whittemore, AS; Wik, Elisabeth; Wilkens, LR; Winterhoff, B; Woo, YL; Wu, AH; Xiang, YB; Yang, HP; Zheng, W; Ziogas, A; Zulkifli, F; Phelan, CM; Iversen, E; Schildkraut, JM; Berchuck, A; Fridley, BL; Goode, EL; Pharoah, PDP; Monteiro, ANA; Sellers, TA; Gayther, SA (Peer reviewed; Journal article, 2013-03-27)
      Epithelial ovarian cancer (EOC) has a heritable component that remains to be fully characterized. Most identified common susceptibility variants lie in non-protein-coding sequences. We hypothesized that variants in the 3′ ...