• Atlantic salmon populations reveal adaptive divergence of immune related genes - a duplicated genome under selection 

      Kjærner-Semb, Erik Nordtorp; Ayllon, Fernando; Furmanek, Tomasz; Wennevik, Vidar; Dahle, Geir; Niemelä, Eero; Ozerov, Mikhail; Vähä, Juha-Pekka; Glover, Kevin; Rubin, Carl J.; Wargelius, Anna; Edvardsen, Rolf (Peer reviewed; Journal article, 2016-08-11)
      Background: Populations of Atlantic salmon display highly significant genetic differences with unresolved molecular basis. These differences may result from separate postglacial colonization patterns, diversifying natural ...
    • Crude oil exposures reveal roles for intracellular calcium cycling in haddock craniofacial and cardiac development 

      Sørhus, Elin; Incardona, John P.; Karlsen, Ørjan; Linbo, Tiffany; Sørensen, Lisbet; Nordtug, Trond; van der Meeren, Terje; Thorsen, Anders; Thorbjørnsen, Maja; Jentoft, Sissel; Edvardsen, Rolf; Meier, Sonnich (Peer reviewed; Journal article, 2016-08-10)
      Recent studies have shown that crude oil exposure affects cardiac development in fish by disrupting excitation-contraction (EC) coupling. We previously found that eggs of Atlantic haddock (Melanogrammus aeglefinus) bind ...
    • Diet affects the redox system in developing Atlantic cod(Gadus morhua) larvae 

      Penglase, Samuel; Edvardsen, Rolf; Furmanek, Tomasz; Rønnestad, Ivar; Karlsen, Ørjan; van der Meeren, Terje; Hamre, Kristin (Peer reviewed; Journal article, 2015-08)
      The growth and development of marine fish larvae fed copepods is superior to those fed rotifers, but the underlying molecular reasons for this are unclear. In the following study we compared the effects of such diets on ...
    • The genome sequence of Atlantic cod reveals a unique immune system 

      Star, Bastiaan; Nederbragt, Alexander Johan; Jentoft, Sissel; Grimholt, Unni; Malmstrøm, Martin; Gregers, Tone Fredsvik; Rounge, Trine Ballestad; Paulsen, Jonas; Solbakken, Monica Hongrø; Sharma, Animesh; Wetten, Ola Frang; Lanzén, Anders; Winer, Roger; Knight, James; Vogel, Jan-Hinnerk; Aken, Bronwen; Andersen, Øivind; Lagesen, Karin; Tooming-Klunderud, Ave; Edvardsen, Rolf; Kirubakaran, G. Tina; Espelund, Mari; Nepal, Chirag; Previti, A. Christopher; Karlsen, Bård Ove; Moum, Truls; Skage, Morten; Berg, Paul Ragnar; Gjøen, Tor; Kuhl, Heiner; Thorsen, Jim; Malde, Ketil; Reinhardt, Richard; Du, Lei; Johansen, Steinar Daae; Searle, Steve; Lien, Sigbjørn; Nilsen, Frank; Jonassen, Inge; Omholt, Stig W; Stenseth, Nils Christian; Jakobsen, Kjetill Sigurd (Peer reviewed; Journal article, 2011-09)
      Atlantic cod (Gadus morhua) is a large, cold-adapted teleost that sustains long-standing commercial fisheries and incipient aquaculture. Here we present the genome sequence of Atlantic cod, showing evidence for complex ...
    • Human-induced evolution caught in action: SNP-array reveals rapid amphi-atlantic spread of pesticide resistance in the salmon ecotoparasite Lepeophtheirus salmonis 

      Besnier, Francois; Kent, Matthew; Skern-Mauritzen, Rasmus; Lien, Sigbjørn; Malde, Ketil; Edvardsen, Rolf; Taylor, Simon; Ljungfeldt, Lina; Nilsen, Frank; Glover, Kevin (Peer reviewed; Journal article, 2014-10-26)
      Background: The salmon louse, Lepeophtheirus salmonis, is an ectoparasite of salmonids that causes huge economic losses in salmon farming, and has also been causatively linked with declines of wild salmonid populations. ...
    • The influence of vgll3 genotypes on sea age at maturity is altered in farmed mowi strain Atlantic salmon 

      Ayllon, Fernando; Solberg, Monica Favnebøe; Glover, Kevin; Mohammadi, Faezeh; Kjærner-Semb, Erik Nordtorp; Fjelldal, Per Gunnar; Andersson, Eva; Hansen, Tom Johnny; Edvardsen, Rolf; Wargelius, Anna (Peer reviewed; Journal article, 2019-05-06)
      Background: In Atlantic salmon in the wild, age at maturity is strongly influenced by the vgll3 locus. Under farming conditions, light, temperature and feeding regimes are known significantly advance or delay age at maturity. ...
    • Molecular evidence that only two opsin subfamilies, the blue light- (SWS2) and green light-sensitive (RH2), drive color vision in Atlantic cod (Gadus morhua) 

      Valen, Ragnhild; Edvardsen, Rolf; Søviknes, Anne Mette; Drivenes, Øyvind; Helvik, Jon Vidar (Peer reviewed; Journal article, 2014-12-31)
      Teleosts show a great variety in visual opsin complement, due to both gene duplication and gene loss. The repertoire ranges from one subfamily of visual opsins (scotopic vision) including rod opsin only retinas seen in ...
    • The two-step development of a duplex retina involves distinct events of cone and rod neurogenesis and differentiation 

      Valen, Ragnhild; Eilertsen, Mariann; Edvardsen, Rolf; Furmanek, Tomasz; Rønnestad, Ivar; van der Meeren, Terje; Karlsen, Ørjan; Nilsen, Tom Ole; Helvik, Jon Vidar (Peer reviewed; Journal article, 2016-08)
      Unlike in mammals, persistent postembryonic retinal growth is a characteristic feature of fish, which includes major remodeling events that affect all cell types including photoreceptors. Consequently, visual capabilities ...
    • Vgll3 and the Hippo pathway are regulated in Sertoli cells upon entry and during puberty in Atlantic salmon testis 

      Kjærner-Semb, Erik Nordtorp; Ayllon, Fernando; Kleppe, Lene; Sørhus, Elin; Skaftnesmo, Kai Ove; Furmanek, Tomasz; Segafredo, Frida Thyri; Thorsen, Anders; Fjelldal, Per Gunnar; Hansen, Tom Johnny; Taranger, Geir Lasse; Andersson, Eva; Schulz, Rüdiger W.; Wargelius, Anna; Edvardsen, Rolf (Peer reviewed; Journal article, 2018-01-30)
      Vgll3 is linked to age at maturity in Atlantic salmon (Salmo salar). However, the molecular mechanisms involving Vgll3 in controlling timing of puberty as well as relevant tissue and cell types are currently unknown. Vgll3 ...
    • The vgll3 Locus Controls Age at Maturity in Wild and Domesticated Atlantic Salmon(Salmo salar L.) Males 

      Ayllon, Fernando; Kjærner-Semb, Erik Nordtorp; Furmanek, Tomasz; Wennevik, Vidar; Solberg, Monica Favnebøe; Dahle, Geir; Taranger, Geir Lasse; Glover, Kevin; Sällman Almèn, Markus; Rubin, Carl J.; Edvardsen, Rolf; Wargelius, Anna (Peer reviewed; Journal article, 2015-11-09)
      Wild and domesticated Atlantic salmon males display large variation for sea age at sexual maturation, which varies between 1–5 years. Previous studies have uncovered a genetic predisposition for variation of age at maturity ...