• The chemical defensome of five model teleost fish 

      Eide, Marta; Zhang, Xiaokang; Karlsen, Odd André; Goldstone, Jared V.; Stegeman, John; Jonassen, Inge; Goksøyr, Anders (Journal article; Peer reviewed, 2021)
      How an organism copes with chemicals is largely determined by the genes and proteins that collectively function to defend against, detoxify and eliminate chemical stressors. This integrative network includes receptors and ...
    • Independent losses of a xenobiotic receptor across teleost evolution 

      Eide, Marta; Rydbeck, Halfdan; Tørresen, Ole K.; Lille-Langøy, Roger; Puntervoll, Pål; Goldstone, Jared V.; Jakobsen, Kjetill Sigurd; Stegeman, John; Goksøyr, Anders; Karlsen, Odd Andre (Peer reviewed; Journal article, 2018-07-10)
      Sensitivity to environmental stressors largely depend on the genetic complement of the organism. Recent sequencing and assembly of teleost fish genomes enable us to trace the evolution of defense genes in the largest and ...
    • Integrative omics-analysis of lipid metabolism regulation by peroxisome proliferator-activated receptor a and b agonists in male Atlantic cod 

      Eide, Marta; Goksøyr, Anders; Yadetie, Fekadu; Gilabert, Alejandra; Bartosova, Zdenka; Frøysa, Håvard Guldbrandsen; Fallahi, Shirin; Zhang, Xiaokang; Blaser, Nello; Jonassen, Inge; Bruheim, Per; Alendal, Guttorm; Brun, Morten; Porte, Cinta; Karlsen, Odd André (Journal article; Peer reviewed, 2023-03-22)
      Lipid metabolism is essential in maintaining energy homeostasis in multicellular organisms. In vertebrates, the peroxisome proliferator-activated receptors (PPARs, NR1C) regulate the expression of many genes involved in ...
    • Liver transcriptome analysis of Atlantic cod (Gadus morhua) exposed to PCB 153 indicates effects on cell cycle regulation and lipid metabolism 

      Yadetie, Fekadu; Karlsen, Odd André; Eide, Marta; Hogstrand, Christer; Goksøyr, Anders (Peer reviewed; Journal article, 2014-06-17)
      Background: Polychlorinated biphenyls (PCBs) are persistent organic pollutants (POPs) with harmful effects in animals and humans. Although PCB 153 is one of the most abundant among PCBs detected in animal tissues, its ...
    • ReCodLiver0.9: Overcoming Challenges in Genome-Scale Metabolic Reconstruction of a Non-model Species 

      Hanna, Eileen Marie; Zhang, Xiaokang; Eide, Marta; Fallahi, Shirin; Furmanek, Tomasz; Yadetie, Fekadu; Zielinski, Daniel Craig; Goksøyr, Anders; Jonassen, Inge (Journal article; Peer reviewed, 2020-11)
      The availability of genome sequences, annotations, and knowledge of the biochemistry underlying metabolic transformations has led to the generation of metabolic network reconstructions for a wide range of organisms in ...