• Cognitive function in patients with neuroborreliosis: A prospective cohort study from the acute phase to 12 months post treatment 

      Andreassen, Silje; Solheim, Anne Marit; Ljøstad, Unn; Mygland, Åse Daasvand; Lorentzen, Åslaug Rudjord; Reiso, Harald; Beyer, Mona Kristiansen; Harbo, Hanne-Cathrin Flinstad; Løhaugen, Gro; Eikeland, Randi (Journal article; Peer reviewed, 2022)
      Background Long-term cognitive problems after neuroborreliosis treatment remain a subject of debate. We have previously shown that cognitive problems are not present in the acute phase of neuroborreliosis, although fatigue ...
    • Enhancement of cranial nerves in Lyme neuroborreliosis: incidence and correlation with clinical symptoms and prognosis 

      Lindland, Elisabeth Margrete Stokke; Solheim, Anne Marit; Dareez, Muhammad Nazeer; Eikeland, Randi; Ljøstad, Unn; Mygland, Åse Daasvand; Reiso, Harald; Lorentzen, Åslaug Rudjord; Harbo, Hanne; Beyer, Mona Kristiansen (Journal article; Peer reviewed, 2022)
      Purpose Symptoms of cranial neuritis are a common presentation of Lyme neuroborreliosis (LNB). Imaging studies are scarce and report contradictory low prevalence of enhancement compared to clinical studies of cranial ...
    • European neuroborreliosis: Long term follow-up 

      Eikeland, Randi (Doctoral thesis, 2012-06-15)
      Lyme disease is the most common human tick borne disease in the northern hemisphere, and the southern coastline of Norway is a high endemic region regarding Lyme disease. European Lyme neuroborreliosis (LNB) often presents ...
    • European neuroborreliosis: neuropsychological findings 30 months post-treatment 

      Eikeland, Randi; Ljøstad, Unn; Mygland, Åse; Herlofson, Karen; Løhaugen, G. C. (Peer reviewed; Journal article, 2011)
      Background: The aim of this study was to compare neuropsychological (NP) functioning in patients with Lyme neuroborreliosis (LNB) 30 months after treatment to matched controls. Methods: We tested 50 patients with LNB and ...
    • Imaging in Lyme neuroborreliosis 

      Lindland, Elisabeth Margrete Stokke; Solheim, Anne Marit; Andreassen, Silje; Paulsen, Else Quist; Eikeland, Randi; Ljøstad, Unn; Mygland, Åse; Elsais, Ahmed; Nygaard, Gro Owren; Lorentzen, Åslaug Rudjord; Harbo, Hanne Flinstad; Beyer, Mona K. (Peer reviewed; Journal article, 2018-10)
      Lyme neuroborreliosis (LNB) is a tick-borne spirochetal infection with a broad spectrum of imaging pathology. For individuals who live in or have travelled to areas where ticks reside, LNB should be considered among ...
    • Low vitamin D, but not tobacco use or high BMI, is associated with long-term disability progression in multiple sclerosis 

      Wesnes, Kristin; Myhr, Kjell-Morten; Riise, Trond; Stokke, Silje Agnethe; Torkildsen, Øivind; Wergeland, Stig; Holmøy, Trygve; Midgard, Rune; Bru, Alla Nikolajevna S; Edland, Astrid; Eikeland, Randi; Gosal, Sonia; Harbo, Hanne Flinstad; Kleveland, Grethe; Sørenes, Yvonne; Øksendal, Nina; Bjørnevik, Kjetil Lauvland (Journal article; Peer reviewed, 2021)
      Background: Low vitamin D levels, tobacco use and high body mass index (BMI) have been linked to adverse disease outcomes in multiple sclerosis (MS), but their influence on long-term disability progression remains unclear. ...
    • Lyme neuroborreliosis with encephalitis; a systematic literature review and a Scandinavian cohort study 

      Knudtzen, Fredrikke Christie; Eikeland, Randi; Bremell, Daniel; Paulsen, Else Quist; Johansen, Isik Somuncu; Solheim, Anne Marit; Skarphédinsson, Sigurdur (Journal article; Peer reviewed, 2022)
      Background Lyme neuroborreliosis (LNB) presenting with encephalitis is rare and scarcely described. Objectives To describe the available literature on LNB encephalitis and to characterize this patient group through a ...
    • Patient-reported outcome after treatment for definite Lyme neuroborreliosis 

      Eikeland, Randi; Ljøstad, Unn; Helgeland, Geir; Sand, Geir; Flemmen, Heidi Øyen; Bø, Margrete Halvorsen; Nordaa, Ludmila; Owe, Jone Furulund; Mygland, Åse; Lorentzen, Åslaug Rudjord (Journal article; Peer reviewed, 2020)
      Objective To chart patient‐reported outcome measures (PROMs) in Norwegian patients treated for definite neuroborreliosis (NB). Material and Methods Adult patients treated for definite NB 1–10 years earlier supplied ...
    • Risk factors for a non-favourable outcome after treated European Neuroborreliosis 

      Eikeland, Randi; Mygland, Åse; Herlofson, Karen; Ljøstad, Unn (Journal article, 2011)
      Aim: To identify risk factors for a non-favourable long term outcome with respect to Health Related Quality of Life (HRQoL) and fatigue after treated Lyme Neuroborreliosis (LNB). Methods: We followed 50 LNB patients, and ...
    • Serum neurofilament as a predictor of 10-year grey matter atrophy and clinical disability in multiple sclerosis: a longitudinal study 

      Lie, Ingrid Anne; Kacar, Sezgi; Wesnes, Kristin; Brouwer, Iman; Kvistad, Silje S.; Wergeland, Stig; Holmøy, Trygve; Midgard, Rune; Bru, Alla Nikolajevna S; Edland, Astrid; Eikeland, Randi; Gosal, Sonia; Harbo, Hanne-Cathrin Flinstad; Kleveland, Grethe; Sørenes, Yvonne; Øksendal, Nina; Varhaug, Kristin Nielsen; Vedeler, Christian Alexander; Barkhof, Frederik; Teunissen, Charlotte E.; Bø, Lars; Torkildsen, Øivind Fredvik Grytten; Myhr, Kjell-Morten; Vrenken, Hugo (Journal article; Peer reviewed, 2022)
      Background The predictive value of serum neurofilament light chain (sNfL) on long-term prognosis in multiple sclerosis (MS) is still unclear. Objective Investigate the relation between sNfL levels over a 2-year ...
    • Six versus 2 weeks treatment with doxycycline in European Lyme neuroborreliosis: a multicentre, noninferiority, double-blinded, randomised and placebocontrolled trial 

      Solheim, Anne Marit; Lorentzen, Åslaug Rudjord; Dahlberg, Audun Olav; Flemmen, Heidi Øyen; Brune, Synne; Forselv, Kristine Johanne Nordstrøm; Pripp, Are Hugo; Bø, Margrete Halvorsen; Eikeland, Randi; Reiso, Harald; Mygland, Åse Daasvand; Ljøstad, Unn (Journal article; Peer reviewed, 2022)
      Background There is limited evidence regarding optimal duration of antibiotic treatment in neuroborreliosis. We aimed to compare efficacy and safety of oral doxycycline for 2 and 6 weeks in European Lyme neuroborreliosis ...