Blar i Bergen Open Research Archive på forfatter "Ellingsen, Ståle"
-
Chip protein U-box domain truncation affects Purkinje neuron morphology and leads to behavioral changes in zebrafish
Pakdaman, Yasaman; Denker, Elsa; Austad, Eirik; Norton, William H.J.; Rolfsnes, Hans Olav; Bindoff, Laurence Albert; Tzoulis, Charalampos; Aukrust, Ingvild; Knappskog, Per Morten; Johansson, Stefan; Ellingsen, Ståle (Journal article; Peer reviewed, 2021-09-24)The ubiquitin ligase CHIP (C-terminus of Hsc70-interacting protein) is encoded by STUB1 and promotes ubiquitination of misfolded and damaged proteins. CHIP deficiency has been linked to several diseases, and mutations in ... -
Cooperative learning goes online: teaching and learning intervention in a digital environment impacts psychosocial outcomes in biology students
Møgelvang, Anja; Vandvik, Vigdis; Ellingsen, Ståle; Strømme, Christian Bianchi; Cotner, Sehoya Harris (Journal article; Peer reviewed, 2023)Identifying evidence-based teaching and learning strategies that can ease teacher challenges and mitigate student concerns in digital settings becomes increasingly important. In this intervention study we compared the ... -
Genetic Dominant Variants in STUB1, Segregating in Families with SCA48, Display In Vitro Functional Impairments Indistinctive from Recessive Variants Associated with SCAR16
Pakdaman, Yasaman; Berland, Siren; Bustad, Helene J.; Erdal, Sigrid; Thompson, Bryony A.; James, Paul A.; Power, Kjersti; Ellingsen, Ståle; Krooni, Martin; Berge, Line Iden; Sexton, Adrienne; Bindoff, Laurence Albert; Knappskog, Per Morten; Johansson, Stefan; Aukrust, Ingvild (Journal article; Peer reviewed, 2021)Variants in STUB1 cause both autosomal recessive (SCAR16) and dominant (SCA48) spinocerebellar ataxia. Reports from 18 STUB1 variants causing SCA48 show that the clinical picture includes later-onset ataxia with a cerebellar ... -
Initial (March 2023) uses and perceptions of ChatGPT in a sample of students and instructors at the University of Bergen (UiB), Norway
Møgelvang, Anja; Bjune, Anne E.; Coelho, Raquel; Cotner, Sehoya; Grellscheid, David; Ellingsen, Ståle (SLATE Research Report;2023-1, Research report, 2023-06)The spring semester of 2023 in higher education was impacted by the release of Large Language Models (LLMs) to the general public. OpenAI’s ChatGPT was at the forefront, with Google's Bard, Microsoft’s Bing, and others ... -
Me, myself and I -Teachers’ self-motivation and sense of responsibility determine the use of active learning methods
Enberg, Katja; Steen, Ida Helene; Ellingsen, Ståle (Journal article; Peer reviewed, 2019)Extended use of laboratory and field courses makes biology a discipline considering itself as a habitual practitioner of active learning strategies. We investigated how widely the faculty at the Department of Biological ... -
Role of the Neutral Amino Acid Transporter SLC7A10 in Adipocyte Lipid Storage, Obesity and Insulin Resistance
Jersin, Regine Åsen; Tallapragada, Divya Sri Priyanka; Madsen, André; Skartveit, Linn; Fjære, Even; McCann, Adrian; Dyer, Laurence; Willems, Aron; Bjune, Jan-Inge; Bjune, Mona Synnøve; Våge, Villy; Nielsen, Hans Jørgen; Thorsen, Håvard Luong; Nedrebø, Bjørn Gunnar; Busch, Christian; Steen, Vidar M.; Blüher, Matthias; Jacobson, Peter; Svensson, Per-Arne; Fernø, Johan; Rydén, Mikael; Arner, Peter; Nygård, Ottar; Claussnitzer, Melina; Ellingsen, Ståle; Madsen, Lise; Sagen, Jørn V.; Mellgren, Gunnar; Dankel, Simon N (Journal article; Peer reviewed, 2021)Elucidation of mechanisms that govern lipid storage, oxidative stress, and insulin resistance may lead to improved therapeutic options for type 2 diabetes and other obesity-related diseases. Here, we find that adipose ... -
The selenium content of SEPP1 versus selenium requirements in vertebrates
Penglase, Samuel; Hamre, Kristin; Ellingsen, Ståle (Peer reviewed; Journal article, 2015-09-10)Selenoprotein P (SEPP1) distributes selenium (Se) throughout the body via the circulatory system. For vertebrates, the Se content of SEPP1 varies from 7 to 18 Se atoms depending on the species, but the reason for this ... -
Sequence analysis and spatiotemporal developmental distribution of the Cat-1-type transporter slc7a1a in zebrafish (Danio rerio)
Ellingsen, Ståle; Narawane, Shailesh; Fjose, Anders; Verri, Tiziano; Rønnestad, Ivar (Journal article; Peer reviewed, 2020)Cationic amino acid transporter 1 (Cat-1 alias Slc7a1) is a Na+-independent carrier system involved in transport and absorption of the cationic amino acids lysine, arginine, histidine, and ornithine and has also been shown ... -
“We’re in this together”: responding to student concerns about large language models in higher education
Coelho, Raquel; Alme, Johan; Asbjørnsen, Helene; Bjune, Anne E.; Cotner, Sehoya; Dahle, Helge; Ellingsen, Ståle; Grellscheid, David; Munthe-Kaas, Antonella Zanna; Nerheim, Magnus Svendsen; Solheim, Belinda Munoz; van der Bilt, Willem Godert Maria (SLATE Research Report;2024-1, Research report, 2024-03-20)We, the self-proclaimed “LLMs in Education” group, comprising university educators (and one partner researcher) from the University of Bergen, Norway, conducted two workshops in August and December 2023 to explore the use ... -
The zebrafish cationic amino acid transporter/glycoprotein-associated family: sequence and spatiotemporal distribution during development of the transport system b 0,+ (slc3a1/slc7a9)
Ellingsen, Ståle; Narawane, Shailesh; Fjose, Anders; Verri, Tiziano; Rønnestad, Ivar (Journal article; Peer reviewed, 2021)System b0,+ absorbs lysine, arginine, ornithine, and cystine, as well as some (large) neutral amino acids in the mammalian kidney and intestine. It is a heteromeric amino acid transporter made of the heavy subunit SLC3A1/rBAT ...