• Cancer Biomarkers: Ethics, Economics and Society 

      Blanchard, Anne; Strand, Roger; Cairns, John Alexander; Tranvåg, Eirik Joakim; Norheim, Ole Frithjof; Seo, Mikyung Kelly; Wik, Elisabeth; Engen, Caroline Benedicte Nitter; Blasimme, Alessandro; Fleck, Leonard M. (Book, 2017)
    • Exploring the boundaries of precision haemato-oncology : The case of FLT3 length mutated acute myeloid leukaemia 

      Engen, Caroline Benedicte Nitter (Doctoral thesis, 2020-02-14)
      This dissertation explores the astounding biological heterogeneity of acute myeloid leukaemia (AML). In three research papers, we study FLT3 length mutated (LM) AML to contribute to the characterisation of genetic diversity ...
    • Filled with Desire, Perceive Molecules 

      Strand, Roger; Engen, Caroline Benedicte Nitter (Chapter, 2022)
      Could there be a Taoist philosophy of Acute Myeloid Leukaemia (AML)? This chapter discusses why a molecular treatment of AML has been so hard to find but still so intensely researched, and exposes some of the ethical ...
    • Reframing cancer: challenging the discourse on cancer and cancer drugs—a Norwegian perspective 

      Stenmarck, Mille Sofie; Engen, Caroline Benedicte Nitter; Strand, Roger (Journal article; Peer reviewed, 2021)
      Background As the range of therapeutic options in the field of oncology increases, so too does the strain on health care budgets. The imbalance between what is medically possible and financially feasible is frequently ...
    • Sex disparity in acute myeloid leukaemia with FLT3 internal tandem duplication mutations: implications for prognosis 

      Hellesøy, Monica; Engen, Caroline Benedicte Nitter; Grob, Tim; Löwenberg, Bob; Valk, Peter J. M.; Gjertsen, Bjørn T. (Journal article; Peer reviewed, 2021)
      Incidence, molecular presentation and outcome of acute myeloid leukaemia (AML) are influenced by sex, but little attention has been directed at untangling sex-related molecular and phenotypic differences between female and ...
    • Titrating complex mass cytometry panels 

      Gullaksen, Stein-Erik; Bader, Lucius; Hellesøy, Monica; Sulen, Andre; Fagerholt, Oda Helen Eck; Engen, Caroline Benedicte Nitter; Skavland, Jørn; Gjertsen, Bjørn Tore; Gavasso, Sonia (Peer reviewed; Journal article, 2019-07-13)
      We describe here a simple and efficient antibody titration approach for cell‐surface markers and intracellular cell signaling targets for mass cytometry. The iterative approach builds upon a well‐characterized backbone ...