Blar i Bergen Open Research Archive på forfatter "Ersland, Kari Merete"

Viser treff 1-7 av 7

    • DCLK1 Variants Are Associated across Schizophrenia and Attention Deficit/Hyperactivity Disorder 

      Håvik, Bjarte; Fernandes, Carla P. D.; Christoforou, Andrea; Ersland, Kari Merete; Giddaluru, Sudheer; Cichon, Sven; Steen, Vidar Martin; Hellard, Stéphanie Le; Johansson, Stefan; Bramham, Clive R.; Haavik, Jan (Peer reviewed; Journal article, 2012-04-23)
      Doublecortin and calmodulin like kinase 1 (DCLK1) is implicated in synaptic plasticity and neurodevelopment. Genetic variants in DCLK1 are associated with cognitive traits, specifically verbal memory and general cognition. ...

    • Exploring lithium's transcriptional mechanisms of action in bipolar disorder: a multi-step study 

      Akkouh, Ibrahim; Skrede, Silje; Holmgren, Asbjørn; Ersland, Kari Merete; Hansson, Lars Johan Axel; Bahrami, Shahram; Andreassen, Ole Andreas; Steen, Vidar Martin; Djurovic, Srdjan; Hughes, Timothy (Peer reviewed; Journal article, 2019)
      Lithium has been the first-line treatment for bipolar disorder (BD) for more than six decades. Although the molecular effects of lithium have been studied extensively and gene expression changes are generally believed to ...

    • Gene expression in the rat brain: High similarity but unique differences between frontomedial-, temporal- and occipital cortex 

      Stansberg, Christine; Ersland, Kari Merete; Valk, Paul van der; Steen, Vidar Martin (Peer reviewed; Journal article, 2011-01-26)
      Background: The six-layered neocortex of the mammalian brain may appear largely homologous, but is in reality a modular structure of anatomically and functionally distinct areas. However, global gene expression seems to ...

    • Gene-Based Analysis of Regionally Enriched Cortical Genes in GWAS Data Sets of Cognitive Traits and Psychiatric Disorders 

      Ersland, Kari Merete; Christoforou, Andrea; Stansberg, Christine; Espeseth, Thomas; Mattheisen, Manuel; Mattingsdal, Morten; Hardarson, Gudmundur A.; Hansen, Thomas; Fernandes, Carla P. D.; Giddaluru, Sudheer; Breuer, René; Strohmaier, Jana; Djurovic, Srdjan; Nöthen, Markus M.; Rietschel, Marcella; Lundervold, Astri Johansen; Werge, Thomas; Cichon, Sven; Andreassen, Ole Andreas; Reinvang, Ivar; Steen, Vidar Martin; Le Hellard, Stephanie (Peer reviewed; Journal article, 2012-02-22)
      Background: Despite its estimated high heritability, the genetic architecture leading to differences in cognitive performance remains poorly understood. Different cortical regions play important roles in normal cognitive ...

    • Identification and characterisation of regionally enriched cortex genes in the rat brain 

      Ersland, Kari Merete (Doctoral thesis, 2012-06-14)

    • LOC689986, a unique gene showing specific expression in restricted areas of the rodent neocortex 

      Ersland, Kari Merete; Håvik, Bjarte; Rinholm, Johanne Egge; Gundersen, Vidar; Stansberg, Christine; Steen, Vidar Martin (Peer reviewed; Journal article, 2013-07-11)
      Background: The neocortex is a highly specialised and complex brain structure, involved in numerous tasks, ranging from processing and interpretation of somatosensory information, to control of motor functions. The normal ...

    • One-Year Treatment with Olanzapine Depot in Female Rats: Metabolic Effects 

      Ersland, Kari Merete; Myrmel, Lene Secher; Fjære, Even; Berge, Rolf Kristian; Madsen, Lise; Steen, Vidar Martin; Skrede, Silje (Peer reviewed; Journal article, 2019-05)
      Background: Antipsychotic drugs can negatively affect the metabolic status of patients, with olanzapine as one of the most potent drugs. While patients are often medicated for long time periods, experiments in rats typically ...