Blar i Bergen Open Research Archive på forfatter "Ewe, Chee Kiang"

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    • Evolution and developmental system drift in the endoderm gene regulatory network of Caenorhabditis and other nematodes 

      Ewe, Chee Kiang; Torres Cleuren, Yamila Nicole; Rothman, Joel H (Journal article; Peer reviewed, 2020)
      Developmental gene regulatory networks (GRNs) underpin metazoan embryogenesis and have undergone substantial modification to generate the tremendous variety of animal forms present on Earth today. The nematode Caenorhabditis ...

    • Extensive intraspecies cryptic variation in an ancient embryonic gene regulatory network 

      Torres Cleuren, Yamila Nicole; Ewe, Chee Kiang; Chipman, Kyle C; Mears, Emily R; Wood, Cricket G; Al-Alami, Coco Emma Alma; Alcorn, Melissa R; Turner, Thomas L; Joshi, Pradeep M; Snell, Russell G; Rothman, Joel H (Peer reviewed; Journal article, 2019-08-15)
      Innovations in metazoan development arise from evolutionary modification of gene regulatory networks (GRNs). We report widespread cryptic variation in the requirement for two key regulatory inputs, SKN-1/Nrf2 and MOM-2/Wnt, ...