Blar i Bergen Open Research Archive på forfatter "Fedøy, Anita-Elin"
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Activation mechanism and activity of globupain, a thermostable C11 protease from the Arctic Mid-Ocean Ridge hydrothermal system
Røyseth, Victoria; M. Hurysz, Brianna; Kaczorowska, Anna-Karina; Dorawa, Sebastian; Fedøy, Anita-Elin; Arsin, Hasan; Sá M. Serafim, Mateus; A. Myers, Samuel; Werbowy, Olesia; Kaczorowski, Tadeusz; Stokke, Runar; O'Donoghue, Anthony J.; Steen, Ida Helene (Journal article; Peer reviewed, 2023)Deep-sea hydrothermal vents offer unique habitats for heat tolerant enzymes with potential new enzymatic properties. Here, we present the novel C11 protease globupain, which was prospected from a metagenome-assembled genome ... -
The complex structures of isocitrate dehydrogenase from Clostridium thermocellum and Desulfotalea psychrophila support a new active site locking mechanism
Leiros, Hanna-Kirsti S.; Fedøy, Anita-Elin; Leiros, Ingar; Steen, Ida Helene (Peer reviewed; Journal article, 2012)Isocitrate dehydrogenase (IDH) catalyzes the oxidative NAD(P)+-dependent decarboxylation of isocitrate into α-ketoglutarate and CO2 and is present in organisms spanning the biological range of temperature. We have solved ... -
Isolation and complete genome sequence of the thermophilic Geobacillus sp. 12AMOR1 from an Arctic deep-sea hydrothermal vent site
Wissuwa, Juliane; Stokke, Runar; Fedøy, Anita-Elin; Lian, Kjersti; Smalås, Arne O.; Steen, Ida Helene (Peer reviewed; Journal article, 2016-02-24)Members of the genus Geobacillus have been isolated from a wide variety of habitats worldwide and are the subject for targeted enzyme utilization in various industrial applications. Here we report the isolation and complete ... -
Tailoring Hydrothermal Vent Biodiversity Toward Improved Biodiscovery Using a Novel in situ Enrichment Strategy
Stokke, Runar; Reeves, Eoghan; Dahle, Håkon; Fedøy, Anita-Elin; Viflot, Thomas Øfstegaard; Onstad, Solveig L.; Vulcano, Francesca; Pedersen, Rolf Birger; Eijsink, Vincent; Steen, Ida Helene (Journal article; Peer reviewed, 2020)Deep-sea hydrothermal vents are amongst the most extreme environments on Earth and represent interesting targets for marine bioprospecting and biodiscovery. The microbial communities in hydrothermal vents are often dominated ...