• Accuracy of surgical complication rate estimation using ICD-10 codes 

      Storesund, Anette; Haugen, Arvid Steinar; Hjortås, Magnus; Nortvedt, Monica Wammen; Flaatten, Hans; Eide, Geir Egil; Boermeester, Marja A.; Sevdalis, Nick; Søfteland, Eirik (Peer reviewed; Journal article, 2019-02)
      Background: The ICD‐10 codes are used globally for comparison of diagnoses and complications, and are an important tool for the development of patient safety, healthcare policies and the health economy. The aim of this ...
    • Adverse events and in-hospital mortality: An analysis of all deaths in a Norwegian health trust during 2011 

      Flaatten, Hans; Brattebø, Guttorm; Alme, Bjørn Arild; Berge, Kjersti; Rosland, Jan Henrik; Viste, Asgaut; Bertelsen, Bjørn; Harthug, Stig; Aardal, Sidsel (Peer reviewed; Journal article, 2017-07-06)
      Background: The estimated number of in-hospitals deaths due to adverse events is often different when using data from deceased patients compared with that of a population experiencing adverse events. Methods: The study was ...
    • Aetiology, antimicrobial therapy and outcome of patients with community acquired severe sepsis: a prospective study in a Norwegian university hospital 

      Nygård, Siri Tandberg; Langeland, Nina; Flaatten, Hans; Fanebust, Rune; Haugen, Oddbjørn; Skrede, Steinar (Peer reviewed; Journal article, 2014-03-04)
      Background: Severe sepsis is recognized as an inflammatory response causing organ dysfunction in patients with infection. Antimicrobial therapy is the mainstay of treatment. There is an ongoing demand for local surveillance ...
    • Age, risk, and life expectancy in Norwegian intensive care: a registry-based population modelling study. 

      Lindemark, Frode; Haaland, Øystein Ariansen; Kvåle, Reidar; Flaatten, Hans; Johansson, Kjell Arne (Peer reviewed; Journal article, 2015-05-26)
      Background: Knowledge about the expected life years gained from intensive care unit (ICU) admission could inform priority-setting decisions across groups of ICU patients and across medical specialties. The aim of this study ...
    • A calibration study of SAPS II with Norwegian intensive care registry data 

      Haaland, Øystein Ariansen; Lindemark, Frode; Flaatten, Hans; Kvåle, Reidar; Johansson, Kjell Arne (Peer reviewed; Journal article, 2014-05-12)
      Background Mortality prediction is important in intensive care. The Simplified Acute Physiology Score (SAPS) II is a tool for predicting such mortality. However, the original SAPS II is poorly calibrated to current intensive ...
    • Clinical Efficacy of Combined Surgical Patient Safety System and the World Health Organization’s Checklists in Surgery. A Nonrandomized Clinical Trial 

      Storesund, Anette; Haugen, Arvid Steinar; Flaatten, Hans; Nortvedt, Monica W.; Eide, Geir Egil; Boermeester, Marja A.; Sevdalis, Nick; Tveiten, Øystein; Mahesparan, Ruby; Hjallen, Bjørg Merete; Fevang, Jonas Meling; Størksen, Catrine Hjelle; Thornhill, Heidi Frances; Sjøen, Gunnar Helge; Kolseth, Solveig Moss; Haaverstad, Rune; Sandli, Oda Kristine; Søfteland, Eirik (Peer reviewed; Journal article, 2020)
      Importance: Checklists have been shown to improve patient outcomes in surgery. The intraoperatively used World Health Organization surgical safety checklist (WHO SSC) is now mandatory in many countries. The only evidenced ...
    • Cognitive function and health-related quality of life four years after cardiac arrest 

      Buanes, Eirik Alnes; Gramstad, Arne; Søvig, Karoline Kjellsdotter; Hufthammer, Karl Ove; Flaatten, Hans; Husby, Thomas; Langørgen, Jørund; Heltne, Jon-Kenneth (Peer reviewed; Journal article, 2015-04)
      Aim: Neuropsychological testing has uncovered cognitive impairment in cardiac arrest survivors with good neurologic outcome according to the cerebral performance categories. We investigated cognitive function and health-related ...
    • Costs and expected gain in lifetime health from intensive care versus general ward care of 30,712 individual patients: A distribution-weighted cost-effectiveness analysis 

      Lindemark, Frode; Haaland, Øystein Ariansen; Kvåle, Reidar; Flaatten, Hans; Norheim, Ole Frithjof; Johansson, Kjell Arne (Peer reviewed; Journal article, 2017-08-21)
      Background: Clinicians, hospital managers, policy makers, and researchers are concerned about high costs, increased demand, and variation in priorities in the intensive care unit (ICU). The objectives of this modelling ...
    • Cumulative prognostic score predicting mortality in patients older than 80 years admitted to the ICU 

      de Lange, Dylan W.; Brinkman, Sylvia; Flaatten, Hans; Boumendil, Ariane; Morandi, Alessandro; Andersen, Finn Husøy; Artigas, Antonio; Bertolini, Guido; Cecconi, Maurizio; Christensen, Steffen; Faraldi, Loredana; Fjølner, Jesper; Jung, Christian; Marsh, Brian; Moreno, Rui; Oeyen, Sandra; Öhman, Christina Agwald; Bollen Pinto, Bernardo; de Smet, Anne Marie G.A.; Soliman, Ivo W.; Szczeklik, Wojciech; Valentin, Andreas; Watson, Ximena; Zafeiridis, Tilemachos; Guidet, Bertrand (Peer reviewed; Journal article, 2019-06)
      OBJECTIVES To develop a scoring system model that predicts mortality within 30 days of admission of patients older than 80 years admitted to intensive care units (ICUs). DESIGN Prospective cohort study. SETTING A total of ...
    • Early diagnosis of sepsis in emergency departments, time to treatment, and association with mortality: An observational study 

      Husabø, Gunnar; Nilsen, Roy Miodini; Flaatten, Hans; Solligård, Erik; Frich, Jan C; Bondevik, Gunnar Tschudi; Braut, Geir Sverre; Walshe, Kieran; Harthug, Stig; Hovlid, Einar (Peer reviewed; Journal article, 2020-01-22)
      Background: Early recognition of sepsis is critical for timely initiation of treatment. The first objective of this study was to assess the timeliness of diagnostic procedures for recognizing sepsis in emergency departments. ...
    • Effects of external inspection on sepsis detection and treatment: a study protocol for a quasiexperimental study with a stepped-wedge design 

      Hovlid, Einar; Frich, Jan C; Walshe, Kieran; Nilsen, Roy Miodini; Flaatten, Hans; Braut, Geir Sverre; Helgeland, Jon; Teig, Inger Lise; Harthug, Stig (Peer reviewed; Journal article, 2017)
      Introduction: Inspections are widely used in health care as a means to improve the health services delivered to patients. Despite their widespread use, there is little evidence of their effect. The mechanisms for how ...
    • Effects of external inspections on sepsis detection and treatment: a stepped-wedge study With cluster-level randomisation 

      Husabø, Gunnar; Nilsen, Roy Miodini; Solligård, Erik; Flaatten, Hans; Walshe, Kieran; Frich, Jan C; Bondevik, Gunnar Tschudi; Braut, Geir Sverre; Helgeland, Jon; Harthug, Stig; Hovlid, Einar (Journal article; Peer reviewed, 2020)
      Objective To evaluate the effects of external inspections on (1) hospital emergency departments’ clinical processes for detecting and treating sepsis and (2) length of hospital stay and 30-day mortality. Design Incomplete ...
    • Epidemiology and impact on all-cause mortality of sepsis in Norwegian hospitals: A national retrospective study 

      Knoop, Siri Tandberg; Skrede, Steinar; Langeland, Nina; Flaatten, Hans (Peer reviewed; Journal article, 2017-11-17)
      Background: Although sepsis is the leading cause of death from infection, there are few population-level epidemiological sepsis reports. The impact of sepsis-related deaths on all-cause hospital mortality is insufficiently ...
    • Frailty and survival in elderly intensive care patients in Norway 

      Andersen, Finn Husøy; Haaland, Øystein Ariansen; Klepstad, Pål; Flaatten, Hans (Journal article; Peer reviewed, 2021)
      Background Today, 10%-15% of Norwegian intensive care patients are ≥80 years. This proportion will increase significantly over the next 20 years, but it is unlikely that resources for intensive care increase correspondingly. ...
    • Huge variation in obtaining ethical permission for a non-interventional observational study in Europe 

      de Lange, Dylan W.; Guidet, Bertrand R.; Andersen, Finn Husøy; Artigas, Antonio; Bertolini, Guido; Moreno, Rui; Christensen, Steffen; Cecconi, Maurizio; Agvald-Öhman, Christina; Gradišek, Primož; Jung, Christian; Marsh, Brian J.; Oeyen, Sandra; Bollen Pinto, Bernardo; Szczeklik, Wojciech; Watson, Ximena; Zafeiridis, Tilemachos; Flaatten, Hans (Peer reviewed; Journal article, 2019-06-03)
      Background Ethical approval (EA) must be obtained before medical research can start. We describe the differences in EA for an pseudonymous, non-interventional, observational European study. Methods Sixteen European national ...
    • Long-term survival and quality of life after intensive care for patients 80 years of age or older 

      Andersen, Finn H; Flaatten, Hans; Klepstad, Pål; Romild, Ulla Kristina; Kvåle, Reidar (Peer reviewed; Journal article, 2015-06-03)
      Background: Comparison of survival and quality of life in a mixed ICU population of patients 80 years of age or older with a matched segment of the general population. Methods: We retrospectively analyzed survival of ICU ...
    • Metabolic alkalosis is the most common acid-base disorder in ICU patients 

      Mæhle, Kirsten Vikesland; Haug, Bjørn; Flaatten, Hans; Nielsen, Erik Waage (Journal article, 2014-03-28)
    • Multiple organ failure after trauma affects even long- term survival and functional status 

      Ulvik, Atle; Kvåle, Reidar; Wentzel-Larsen, Tore; Flaatten, Hans (Peer reviewed; Journal article, 2007-09-04)
      Background The aim of this study was to assess the incidence of organ failure in trauma patients treated in an intensive care unit (ICU), and to study the relationship between organ failure and long-term survival and ...
    • Sepsis at ICU admission does not decrease 30-day survival in very old patients: a post-hoc analysis of the VIP1 multinational cohort study 

      Ibarz, Mercedes; Boumendil, Ariane; Flaatten, Hans; Andersen, Finn Husøy; Artigas, Antonio; Haas, Lenneke E. M.; Irazabal, Marian; de Lange, Dylan W.; Morandi, Alessandro; Bertolini, Guido; Cecconi, Maurizio; Christensen, Stefen; Faraldi, Loredana; Fjølner, Jesper; Jung, Christian; Marsh, Brian; Moreno, Rui; Oeyen, Sandra; Öhman, Christina Agwald; Pinto, Bernardo Bollen; Soliman, Ivo W.; Valentin, Andreas; Szczeklik, Wojciech; Watson, Ximena; Zaferidis, Tilemachos; Guidet, Bertrand; Artigas, Antonio (Journal article; Peer reviewed, 2020)
      Background The number of intensive care patients aged ≥ 80 years (Very old Intensive Care Patients; VIPs) is growing. VIPs have high mortality and morbidity and the benefits of ICU admission are frequently questioned. ...
    • Sex-specific outcome disparities in very old patients admitted to intensive care medicine: a propensity matched analysis 

      Wernly, Bernhard; Bruno, Raphael Romano; Kelm, Malte; Boumendil, Ariane; Morandi, Alessandro; Andersen, Finn Husøy; Artigas, Antonio; Finazzi, Stefano; Cecconi, Maurizio; Christensen, Steffen; Faraldi, Loredana; Lichtenauer, Michael; Muessig, Johanna M.; Marsh, Brian; Moreno, Rui; Oeyen, Sandra; Öhman, Christina Agwald; Pinto, Bernadro Bollen; Soliman, Ivo W.; Szczeklik, Wojciech; Niederseer, David; Valentin, Andreas; Watson, Ximena; Leaver, Susannah; Boulanger, Carole; Walther, Sten; Schefold, Jörg C.; Joannidis, Michael; Nalapko, Yuriy; Elhadi, Muhammed; Fjølner, Jesper; Zafeiridis, Tilemachos; De Lange, Dylan W.; Guidet, Bertrand; Flaatten, Hans; Jung, Christian (Journal article; Peer reviewed, 2020)
      Female and male very elderly intensive patients (VIPs) might differ in characteristics and outcomes. We aimed to compare female versus male VIPs in a large, multinational collective of VIPs with regards to outcome and ...