Browsing Bergen Open Research Archive by Author "Fleischer, Thomas"
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DNA methylation changes in response to neoadjuvant chemotherapy are associated with breast cancer survival
Pedersen, Christine Aaserød; Cao, Maria Dung; Fleischer, Thomas; Rye, Morten Beck; Knappskog, Stian; Eikesdal, Hans Petter; Lønning, Per Eystein; Tost, Jörg; Kristensen, Vessela N.; Tessem, May-Britt; Giskeødegård, Guro F.; Bathen, Tone Frost (Journal article; Peer reviewed, 2022)Background: Locally advanced breast cancer is a heterogeneous disease with respect to response to neoadjuvant chemotherapy (NACT) and survival. It is currently not possible to accurately predict who will benefit from the ... -
Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
Klajic, Jovana; Fleischer, Thomas; Dejeux, Emelyne; Edvardsen, Hege; Warnberg, Fredrik; Bukholm, Ida Rashida Khan; Lønning, Per Eystein; Solvang, Hiroko Kato; Børresen-Dale, Anne-Lise; Tost, Jörg; Kristensen, Vessela N. (Peer reviewed; Journal article, 2013-10-05)Background: Aberrant DNA methylation of regulatory genes has frequently been found in human breast cancers and correlated to clinical outcome. In the present study we investigate stage specific changes in the DNA methylation ...