Browsing Bergen Open Research Archive by Author "Fluge, Øystein"

Now showing items 1-15 of 15

    • Activity monitoring and patient-reported outcome measures in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome patients 

      Rekeland, Ingrid Gurvin; Sørland, Kari; Bruland, Ove; Risa, Kristin; Alme, Kine; Dahl, Olav; Tronstad, Karl Johan; Mella, Olav; Fluge, Øystein (Journal article; Peer reviewed, 2022-09-19)
      Introduction: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disease with no validated specific and sensitive biomarker, and no standard approved treatment. In this observational study with no intervention, ...

    • Benefit from B-Lymphocyte Depletion Using the Anti- CD20 Antibody Rituximab in Chronic Fatigue Syndrome. A Double-Blind and Placebo-Controlled Study 

      Fluge, Øystein; Bruland, Ove; Risa, Kristin; Storstein, Anette; Kristoffersen, Einar K.; Sapkota, Dipak; Næss, Halvor; Dahl, Olav; Nyland, Harald; Mella, Olav (Peer reviewed; Journal article, 2011-10-19)
      Background: Chronic fatigue syndrome (CFS) is a disease of unknown aetiology. Major CFS symptom relief during cancer chemotherapy in a patient with synchronous CFS and lymphoma spurred a pilot study of B-lymphocyte depletion ...

    • Butterfly glioblastoma: Clinical characteristics, treatment strategies and outcomes in a population-based cohort 

      Bjorland, Line; Kurz, Kathinka Dæhli; Fluge, Øystein; Gilje, Bjørnar; Mahesparan, Rupavathana; Sætran, Hege Aase; Ushakova, Anastasia; Farbu, Elisabeth (Journal article; Peer reviewed, 2022)
      Background Butterfly glioblastoma is a rare subgroup of glioblastoma with a bihemispheric tumor crossing the corpus callosum, and is associated with a dismal prognosis. Prognostic factors are previously sparsely described ...

    • Endothelial dysfunction in ME/CFS patients 

      Sandvik, Miriam Kristine; Sørland, Kari; Leirgul, Elisabeth; Rekeland, Ingrid Gurvin; Stavland, Christina Særsten; Mella, Olav; Fluge, Øystein (Journal article; Peer reviewed, 2023-02-02)
      Objective: A few earlier studies have found impaired endothelial function in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). The present study investigated large-vessel and small-vessel endothelial ...

    • Fine mapping of the major histocompatibility complex (MHC) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suggests involvement of both HLA class I and class II loci 

      Hajdarevic, Riad; Lande, Asgeir; Rekeland, Ingrid Gurvin; Rydland, Anne; Strand, Elin B.; Sosa, Daysi Duarte; Creary, Lisa E; Mella, Olav; Egeland, Torstein; Saugstad, Ola Didrik; Fluge, Øystein; Lie, Benedicte Alexandra; Viken, Marte Kathrine (Journal article; Peer reviewed, 2021)
      The etiology of myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is unknown, but involvement of the immune system is one of the proposed underlying mechanisms. Human leukocyte antigen (HLA) associations are ...

    • The Geriatric Prognostic Index: a clinical prediction model for survival of older diffuse large B-cell lymphoma patients treated with standard immunochemotherapy 

      Isaksen, Kathrine Thuestad; Galleberg, Renate Berget; Mastroianni, Maria Adele; Rinde, Marit; Rusten, Leiv Sindre; Barzenje, Dlawer Abdulla; Ramslien, Lloyd Frode; Fluge, Øystein; Jordhøy, Marit Slaaen; Meyer, Peter Albert; Liestøl, Knut; Smeland, Erlend Bremertun; Lingjærde, Ole Christian; Holte, Harald; Brodtkorb, Marianne (Journal article; Peer reviewed, 2023)
      The International prognostic Index (IPI) is the most widely used clinical prediction model for diffuse large B-cell lymphoma (DLBCL) patients treated with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone ...

    • Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) 

      Lande, Asgeir; Fluge, Øystein; Strand, Elin Bolle; Flåm, Siri Tennebø; Sosa, Daisy Duarte; Mella, Olav; Egeland, Torstein; Saugstad, Ola Didrik; Lie, Benedicte Alexandra; Viken, Marte K (Journal article; Peer reviewed, 2020)
      The etiology and pathogenesis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) are unknown, and autoimmunity is one of many proposed underlying mechanisms. Human Leukocyte Antigen (HLA) associations are ...

    • Intravenous Cyclophosphamide in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. An Open-Label Phase II Study 

      Rekeland, Ingrid Gurvin; Fosså, Alexander; Lande, Asgeir; Ktoridou-Valen, Irini; Sørland, Kari; Holsen, Mari; Tronstad, Karl Johan; Risa, Kristin; Alme, Kine; Viken, Marte Katrine; Lie, Benedicte Alexandra; Dahl, Olav; Mella, Olav; Fluge, Øystein (Journal article; Peer reviewed, 2020)
      Introduction: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disease with high symptom burden, of unknown etiology, with no established treatment. We observed patients with long-standing ME/CFS who got ...

    • Inverse correlation between PDGFC expression and lymphocyte infiltration in human papillary thyroid carcinoma 

      Bruland, Ove; Fluge, Øystein; Akslen, Lars A.; Eiken, Hans Geir; Lillehaug, Johan; Varhaug, Jan Erik; Knappskog, Per (Peer reviewed; Journal article, 2009-12-08)
      Background: Members of the PDGF family have been suggested as potential biomarkers for papillary thyroid carcinomas (PTC). However, it is known that both expression and stimulatory effect of PDGF ligands can be affected ...

    • A map of metabolic phenotypes in patients with myalgic encephalomyelitis/chronic fatigue syndrome 

      Hoel, Fredrik; Hoel, August; Pettersen, Ina Katrine Nitschke; Rekeland, Ingrid Gurvin; Risa, Kristin; Alme, Kine; Sørland, Kari; Fosså, Alexander; Lien, Katarina; Herder, Ingrid; Thurmer, Hanne; Gotaas, Merethe Otelie Eide; Schäfer, Christoph; Berge, Rolf K.; Sommerfelt, Kristian; Marti, Hans Peter; Dahl, Olav; Mella, Olav; Fluge, Øystein; Tronstad, Karl Johan (Journal article; Peer reviewed, 2021)
      Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease usually presenting after infection. Emerging evidence supports that energy metabolism is affected in ME/CFS, but a unifying metabolic ...

    • Metabolic analysis of amino acids and vitamin B6 pathways in lymphoma survivors with cancer related chronic fatigue 

      Fosså, Alexander; Smeland, Knut Bjøro; Fluge, Øystein; Tronstad, Karl Johan; Loge, Jon Håvard; Midtun, Øyvind; Ueland, Per Magne; Kiserud, Cecilie E. (Journal article; Peer reviewed, 2020)
      Chronic cancer-related fatigue (CF) is a common and distressing condition in a subset of cancer survivors and common also after successful treatment of malignant lymphoma. The etiology and pathogenesis of CF is unknown, ...

    • No replication of previously reported association with genetic variants in the T cell receptor alpha (TRA) locus for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) 

      Ueland, Marthe; Hajdarevic, Riad; Mella, Olav; Strand, Elin Bolle; Daysi Duarte, Sosa; Saugstad, Ola Didrik; Fluge, Øystein; Lie, Benedicte Alexandra; Viken, Marte Kathrine (Journal article; Peer reviewed, 2022)
      Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disease with a variety of symptoms such as post-exertional malaise, fatigue, and pain, but where aetiology and pathogenesis are unknown. An increasing number ...

    • Reduced Endothelial Function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome–Results From Open-Label Cyclophosphamide Intervention Study 

      Sørland, Kari; Sandvik, Miriam Kristine; Rekeland, Ingrid Gurvin; Ribu, Lis; Småstuen, Milada Cvancarova; Mella, Olav; Fluge, Øystein (Journal article; Peer reviewed, 2021)
      Introduction: Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) present with a range of symptoms including post-exertional malaise (PEM), orthostatic intolerance, and autonomic dysfunction. Dysfunction ...

    • Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome – State of the art: Report of the 2nd international meeting at the Charité Fatigue Center 

      Steiner, Sophie; Fehrer, Annick; Hoheisel, Friederike; Schoening, Simon; Aschenbrenner, Anna; Babel, Nina; Bellmann-Strobl, Judith; Finke, Carsten; Fluge, Øystein; Froehlich, Laura; Goebel, Andreas; Grande, Bettina; Haas, Johannes-Peter; Hohberger, Bettina; Jason, Leonard A.; Komaroff, Anthony L.; Lacerda, Eliana; Liebl, Max; Maier, Andrea; Mella, Olav; Nacul, Luis; Paul, Friedemann; Prusty, Bhupesh K.; Puta, Christian; Riemekasten, Gabriela; Ries, Wolfgang; Rowe, Peter C.; Sawitzki, Birgit; Shoenfeld, Yehuda; Schultze, Joachim L.; Seifert, Martina; Sepúlveda, Nuno; Sotzny, Franziska; Stein, Elisa; Stingl, Michael; Ufer, Friederike; Veauthier, Christian; Westermeier, Francisco; Wirth, Klaus; Wolfarth, Bernd; Zalewski, Pawel; Behrends, Uta; Scheibenbogen, Carmen (Journal article; Peer reviewed, 2023)
      Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a devastating disease affecting millions of people worldwide. Due to the 2019 pandemic of coronavirus disease (COVID-19), we are facing a significant increase ...

    • Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation 

      Pettersen, Ina Katrine Nitschke; Tusubira, Deusdedit; Ashrafi, Hanan; Dyrstad, Sissel Elisabeth; Hansen, Lena; Liu, Xiao-Zheng; Hodneland, Linn I.; Løvsletten, Nils Gunnar; Berge, Kjetil; Wergedahl, Hege; Bjørndal, Bodil; Fluge, Øystein; Bruland, Ove; Rustan, Arild; Halberg, Nils; Røsland, Gro Vatne; Berge, Rolf Kristian; Tronstad, Karl Johan (Peer reviewed; Journal article, 2019)
      Fatty acid oxidation is a central fueling pathway for mitochondrial ATP production. Regulation occurs through multiple nutrient- and energy-sensitive molecular mechanisms. We explored if upregulated mRNA expression of the ...