Browsing Bergen Open Research Archive by Author "Fonnes, Tina"
Now showing items 1-7 of 7
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Cancer awareness in the general population varies with sex, age and media coverage: A population-based survey with focus on gynecologic cancers
Fonnes, Tina; Telle, Ingrid Ovidia Moe; Forsse, David Erik; Falck, Runa; Trovik, Jone; Haldorsen, Ingfrid S.; Krakstad, Camilla (Journal article; Peer reviewed, 2021)Objectives There is a need for more knowledge about the public awareness and attitudes towards gynecologic cancers. We employed a research-purpose population-based citizen panel to assess how often people recall gynecologic ... -
Feasibility and utility of MRI and dynamic 18F-FDG-PET in an orthotopic organoid-based patient-derived mouse model of endometrial cancer
Espedal, Heidi; Berg, Hege Fredriksen; Fonnes, Tina; Fasmer, Kristine Eldevik; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2021)Background: Pelvic magnetic resonance imaging (MRI) and whole-body positron emission tomography-computed tomography (PET-CT) play an important role at primary diagnostic work-up and in detecting recurrent disease in ... -
Imaging of preclinical endometrial cancer models for monitoring tumor progression and response to targeted therapy
Espedal, Heidi; Fonnes, Tina; Fasmer, Kristine Eldevik; Krakstad, Camilla; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2019-11-27)Endometrial cancer is the most common gynecologic malignancy in industrialized countries. Most patients are cured by surgery; however, about 15% of the patients develop recurrence with limited treatment options. Patient-derived ... -
Multimodal Imaging of Orthotopic Mouse Model of Endometrial Carcinoma
Haldorsen, Ingfrid S.; Popa, Mihaela Lucia; Fonnes, Tina; Brekke, Njål; Kopperud, Reidun Kristin; Visser, Nicole C.; Rygh, Cecilie Brekke; Pavlin, Tina; Salvesen, Helga Birgitte; McCormack, Emmet; Krakstad, Camilla (Peer reviewed; Journal article, 2015-08-07)Background: Orthotopic endometrial cancer models provide a unique tool for studies of tumour growth and metastatic spread. Novel preclinical imaging methods also have the potential to quantify functional tumour characteristics ... -
Near-Infrared Fluorescent Imaging for Monitoring of Treatment Response in Endometrial Carcinoma Patient-Derived Xenograft Models.
Fonnes, Tina; Strand, Elin; Fasmer, Kristine Eldevik; Berg, Hege Fredriksen; Espedal, Heidi; Sortland, Kristina; Stefansson, Ingunn; Bjørge, Line; Haldorsen, Ingfrid S.; Krakstad, Camilla; Mc Cormack, Emmet (Journal article; Peer reviewed, 2020)Imaging of clinically relevant preclinical animal models is critical to the development of personalized therapeutic strategies for endometrial carcinoma. Although orthotopic patient-derived xenografts (PDXs) reflecting ... -
Patient-derived organoids reflect the genetic profile of endometrial tumors and predict patient prognosis
Berg, Hege Fredriksen; Hjelmeland, Marta Espevold; Lien, Hilde Eide; Espedal, Heidi; Fonnes, Tina; Srivastava, Aashish; Stokowy, Tomasz; Strand, Elin; Bozickovic, Olivera; Stefansson, Ingunn Marie; Bjørge, Line; Trovik, Jone; Haldorsen, Ingfrid S.; Høivik, Erling Andre; Krakstad, Camilla (Journal article; Peer reviewed, 2021)Background: A major hurdle in translational endometrial cancer (EC) research is the lack of robust preclinical models that capture both inter- and intra-tumor heterogeneity. This has hampered the development of new treatment ... -
Preclinical models and molecular biomarkers. Tools to improve treatment in endometrial carcinoma
Fonnes, Tina (Doctoral thesis, 2018-11-30)Background: Endometrial carcinoma is the fourth most common cancer in European women, and incidence is increasing. No major improvements in treatment or survival have been achieved over the last decades, and an individualized ...