Blar i Bergen Open Research Archive på forfatter "Forsse, David Erik"
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A 10-gene prognostic signature points to LIMCH1 and HLA-DQB1 as important players in aggressive cervical cancer disease
Halle, Mari Kyllesø; Sødal, Marte; Forsse, David Erik; Engerud, Hilde Renate; Woie, Kathrine; Lura, Njål Gjærde; Wagner-Larsen, Kari Strøno; Trovik, Jone; Bertelsen, Bjørn; Haldorsen, Ingfrid S.; Ojesina, Akinyemi I.; Krakstad, Camilla (Journal article; Peer reviewed, 2021)Background: Advanced cervical cancer carries a particularly poor prognosis, and few treatment options exist. Identification of effective molecular markers is vital to improve the individualisation of treatment. We investigated ... -
Blood steroid levels predict survival in endometrial cancer and reflect tumor estrogen signaling
Forsse, David Erik; Tangen, Ingvild Løberg; Fasmer, Kristine Eldevik; Halle, Mari Kyllesø; Viste, Kristin; Almås, Bjørg; Bertelsen, Bjørn-Erik; Trovik, Jone; Haldorsen, Ingfrid S.; Krakstad, Camilla (Peer reviewed; Journal article, 2020-02)Objective Blood-based biomarkers are attractive due to ease of sampling and standardized measurement technology, reducing obstacles to clinical implementation. The objective of this study was to evaluate a clinically ... -
Cancer awareness in the general population varies with sex, age and media coverage: A population-based survey with focus on gynecologic cancers
Fonnes, Tina; Telle, Ingrid Ovidia Moe; Forsse, David Erik; Falck, Runa; Trovik, Jone; Haldorsen, Ingfrid S.; Krakstad, Camilla (Journal article; Peer reviewed, 2021)Objectives There is a need for more knowledge about the public awareness and attitudes towards gynecologic cancers. We employed a research-purpose population-based citizen panel to assess how often people recall gynecologic ... -
Clinicopathological and radiological stratification within FIGO 2018 stages improves risk-prediction in cervical cancer
Halle, Mari Kyllesø; Bozickovic, Olivera; Forsse, David Erik; Wagner-Larsen, Kari Strøno; Gold, Rose Meng; Lura, Njål; Woie, Kathrine; Bertelsen, Bjørn; Haldorsen, Ingfrid S.; Krakstad, Camilla (Journal article; Peer reviewed, 2024)Objective: Assess the added prognostic value of the updated International Federation of Gynecology and Obstetrics (FIGO) 2018 staging system, and to identify clinicopathological and radiological biomarkers for improved ... -
A gene signature identifying CIN3 regression and cervical cancer survival
Halle, Mari Kyllesø; Munk, Ane Cecilie Dæhli; Engesæter, Birgit Øvstebø; Akbari, Saleha; Frafjord, Astri; Høivik, Erling Andre; Forsse, David Erik; Fasmer, Kristine Eldevik; Woie, Kathrine; Haldorsen, Ingfrid S.; Bertelsen, Bjørn; Janssen, Emiel; Gudlaugsson, Einar; Krakstad, Camilla; Øvestad, Irene Tveiterås (Journal article; Peer reviewed, 2021-11-16)The purpose of this study was to establish a gene signature that may predict CIN3 regression and that may aid in selecting patients who may safely refrain from conization. Oncomine mRNA data including 398 immune-related ... -
Interobserver agreement and prognostic impact for MRI–based 2018 FIGO staging parameters in uterine cervical cancer
Wagner-Larsen, Kari Strøno; Lura, Njål Gjærde; Salvesen, Øyvind; Halle, Mari Kyllesø; Forsse, David Erik; Trovik, Jone; Smit, Noeska Natasja; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2022)Objectives To evaluate the interobserver agreement for MRI–based 2018 International Federation of Gynecology and Obstetrics (FIGO) staging parameters in patients with cervical cancer and assess the prognostic value of ... -
Longitudinal effects of adjuvant chemotherapy and lymph node staging on patient-reported outcomes in endometrial cancer survivors: a prospective cohort study
Forsse, David Erik; Barbero, Mark L.; Werner, Henrica Maria Johanna; Woie, Kathrine; Nordskar, Nina Jebens; Berge Nilsen, Elisabeth; Ellstrøm Engh, Marie; Vistad, Ingvild; Rege, Astri; Sævik-Lode, Margaret; Andreasen, Stine; Haldorsen, Ingfrid S.; Trovik, Jone; Krakstad, Camilla (Journal article; Peer reviewed, 2021)Background: Most patients with endometrial cancer with localized disease are effectively treated and survive for a long time. The primary treatment is hysterectomy, to which surgical staging procedures may be added to ... -
Maintained survival outcome after reducing lymphadenectomy rates and optimizing adjuvant treatment in endometrial cancer
Forsse, David Erik; Berg, Hege Fredriksen; Bozickovic, Olivera; Engerud, Hilde Renate; Halle, Mari Kyllesø; Høivik, Erling Andre; Woie, Kathrine; Werner, Henrica Maria Johanna; Haldorsen, Ingfrid S.; Trovik, Jone; Krakstad, Camilla (Journal article; Peer reviewed, 2020)Objective: Main controversies in endometrial cancer treatment include the role of lymphadenectomy and optimal adjuvant treatment. We assessed clinical outcome in a population-based endometrial cancer cohort in relation to ... -
Preoperative pelvic MRI and 2-[18F]FDG PET/CT for lymph node staging and prognostication in endometrial cancer—time to revisit current imaging guidelines?
Fasmer, Kristine Eldevik; Gulati, Ankush; Dybvik, Julie Andrea; Wagner-Larsen, Kari Strøno; Lura, Njål Gjærde; Salvesen, Øyvind; Forsse, David Erik; Trovik, Jone; Pijnenborg, Johanna M. A.; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2022)Objective This study presents the diagnostic performance of four different preoperative imaging workups (IWs) for prediction of lymph node metastases (LNMs) in endometrial cancer (EC): pelvic MRI alone (IW1), MRI and ... -
Visceral fat percentage for prediction of outcome in uterine cervical cancer
Eide, Agnes J.; Halle, Mari Kyllesø; Lura, Njål; Fasmer, Kristine Eldevik; Wagner-Larsen, Kari Strøno; Forsse, David Erik; Bertelsen, Bjørn; Salvesen, Øyvind Olav; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2023)Objective The prognostic role of adiposity in uterine cervical cancer (CC) is largely unknown. Abdominal fat distribution may better reflect obesity than body mass index. This study aims to describe computed tomography ... -
What MRI-based tumor size measurement is best for predicting long-term survival in uterine cervical cancer?
Lura, Njål Gjærde; Wagner-Larsen, Kari Strøno; Forsse, David Erik; Trovik, Jone; Halle, Mari Kyllesø; Bertelsen, Bjørn; Salvesen, Øyvind; Woie, Kathrine; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2022-06-17)Background: Tumor size assessment by MRI is central for staging uterine cervical cancer. However, the optimal role of MRI-derived tumor measurements for prognostication is still unclear. Material and methods: This ...