Browsing Bergen Open Research Archive by Author "Fosse, Vibeke Samuelsen"

Now showing items 1-6 of 6

    • CD24-targeted fluorescence imaging in patient-derived xenograft models of high-grade serous ovarian carcinoma 

      Kleinmanns, Katrin; Bischof, Katharina; Anandan, Shamundeeswari; Popa, Mihaela Lucia; Akslen, Lars A.; Gjertsen, Bjørn Tore; Karlsen, Ida; Fosse, Vibeke Samuelsen; Bjørge, Line; Mc Cormack, Emmet (Journal article; Peer reviewed, 2020)
      Background The survival rate of patients with advanced high-grade serous ovarian carcinoma (HGSOC) remains disappointing. Clinically translatable orthotopic cell line xenograft models and patient-derived xenografts (PDXs) ...

    • CD24-targeted intraoperative fluorescence image-guided surgery leads to improved cytoreduction of ovarian cancer in a preclinical orthotopic surgical model 

      Kleinmanns, Katrin; Fosse, Vibeke Samuelsen; Davidson, Ben; de Jalón, Elvira Garcia; Tenstad, Olav; Bjørge, Line; McCormack, Emmet (Journal article; Peer reviewed, 2020)
      Background The completeness of resection is a key prognostic indicator in patients with ovarian cancer, and the application of tumour-targeted fluorescence image-guided surgery (FIGS) has led to improved detection of ...

    • Comparison of Five Near-Infrared Fluorescent Folate Conjugates in an Ovarian Cancer Model 

      García de Jalón, Elvira; Kleinmanns, Katrin; Fosse, Vibeke Samuelsen; Davidson, Ben; Bjørge, Line; Haug, Bengt Erik; McCormack, Emmet (Journal article; Peer reviewed, 2021)
      Purpose Fluorescence imaging (FLI) using targeted near-infrared (NIR) conjugates aids the detection of tumour lesions pre- and intraoperatively. The optimisation of tumour visualisation and contrast is essential and can ...

    • The emerging role of cd24 in cancer theranostics—a novel target for fluorescence image-guided surgery in ovarian cancer and beyond 

      Kleinmanns, Katrin; Fosse, Vibeke Samuelsen; Bjørge, Line; McCormack, Emmet (Journal article; Peer reviewed, 2020)
      Complete cytoreductive surgery is the cornerstone of the treatment of epithelial ovarian cancer (EOC). The application of fluorescence image-guided surgery (FIGS) allows for the increased intraoperative visualization and ...

    • Evaluating Translational Methods for Personalized Medicine—A Scoping Review 

      Fosse, Vibeke Samuelsen; Oldoni, Emanuela; Gerardi, Chiara; Banzi, Rita; Fratelli, Maddalena; Bietrix, Florence; Ussi, Anton; Andreu, Antonio L.; McCormack, Emmet (Journal article; Peer reviewed, 2022)
      The introduction of personalized medicine, through the increasing multi-omics characterization of disease, brings new challenges to disease modeling. The scope of this review was a broad evaluation of the relevance, validity, ...

    • Recommendations for robust and reproducible preclinical research in personalised medicine 

      Fosse, Vibeke Samuelsen; Oldoni, Emanuela; Bietrix, Florence; Budillon, Alfredo; Daskalopoulos, Evnagelos P.; Fratelli, Maddalena; Gerlach, Björn; Groenen, Peter M.A.; Hölter, Sabine M.; Menon, Julia M.L.; Mobasheri, Ali; Osborne, Nikki; Ritskes-Hoitinga, Merel; Ryll, Bettina; Schmitt, Elmar; Ussi, Anton; Andreu, Antonio L.; Mccormack, Emmet Matin (Journal article; Peer reviewed, 2023)
      Background Personalised medicine is a medical model that aims to provide tailor-made prevention and treatment strategies for defined groups of individuals. The concept brings new challenges to the translational step, both ...