Browsing Bergen Open Research Archive by Author "Frøysa, Håvard G"
Now showing items 1-4 of 4
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Experimental design for parameter estimation in steady-state linear models of metabolic networks
Frøysa, Håvard G; Skaug, Hans J.; Alendal, Guttorm (Journal article; Peer reviewed, 2020-01)Metabolic networks are typically large, containing many metabolites and reactions. Dynamical models that aim to simulate such networks will consist of a large number of ordinary differential equations, with many kinetic ... -
New Conceptual Toxicokinetic Model to Assess Synergistic Mixture Effects between the Aromatic Hydrocarbon β-Naphthoflavone and the Azole Nocodazole on the CYP1A Biomarker in a Fish Cell Line
Fallahi, Shirin; Mlnaříková, Marie; Alvord, Charlotte; Alendal, Guttorm; Frøysa, Håvard G; Lundh, Thorbjörn; Celander, Malin C. (Journal article; Peer reviewed, 2020)Toxicokinetic interactions with catabolic cytochrome P450 (CYP) enzymes can inhibit chemical elimination pathways and cause synergistic mixture effects. We have created a mathematical bottom-up model for a synergistic ... -
Northeast Arctic Cod and Prey Match-Mismatch in a High-Latitude Spring-Bloom System
Vikebø, Frode Bendiksen; Broch, Ole Jacob; Kajiya Endo, Clarissa Akemi; Frøysa, Håvard G; Carroll, JoLynn; Juselius, Jonas; Langangen, Øystein Ole Gahr (Journal article; Peer reviewed, 2021)By combining an ocean model, a nutrient-phytoplankton-zooplankton-detritus-model and an individual-based model for early life stages of Northeast Arctic cod we systematically investigate food limitations and growth performance ... -
Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua)
Dale, Karina; Yadetie, Fekadu; Horvli, Torill; Zhang, Xiaokang; Frøysa, Håvard G; Karlsen, Odd André; Goksøyr, Anders (Journal article; Peer reviewed, 2022)The aim of the present study was to investigate effects of per- and polyfluoroalkyl substances (PFAS), both single compounds and a mixture of these, using precision-cut liver slices (PCLS) from Atlantic cod (Gadus morhua). ...