• Activation of Neurotoxic Astrocytes Due to Mitochondrial Dysfunction Triggered by POLG Mutation 

      Liang, Xiao; Chen, Anbin; Kianian, Atefeh; Kristiansen, Cecilie Katrin; Tsering Yangzom, Tsering Yangzom; Furriol Palmer, Jessica; Høyland, Lena Elise; Ziegler, Mathias; Kråkenes, Torbjørn; Tzoulis, Charalampos; Fang, Fei; Sullivan, Gareth John; Bindoff, Laurence Albert (Journal article; Peer reviewed, 2024)
      Mitochondrial diseases are associated with neuronal death and mtDNA depletion. Astrocytes respond to injury or stimuli and damage to the central nervous system. Neurodegeneration can cause astrocytes to activate and acquire ...
    • Glomerular transcriptomics predicts long term outcome and identifies therapeutic strategies for patients with assumed benign IgA nephropathy 

      Rivedal, Mariell Lossius; Mikkelsen, Håvard; Marti, Hans Peter; Liu, Lili; Kiryluk, Krzysztof; Knoop, Thomas; Bjørneklett, Rune Oskar; Haaskjold, Yngvar Lunde; Furriol Palmer, Jessica; Leh, Sabine; Paunas, Flavia Teodora Ioana; Babickova, Janka; Scherer, Andreas; Serre, Camille Julia; Eikrem, Øystein Solberg; Strauss, Philipp (Journal article; Peer reviewed, 2024)
      Some patients diagnosed with benign IgA nephropathy (IgAN) develop a progressive clinical course, not predictable by known clinical or histopathological parameters. To assess if gene expression can differentiate between ...