Browsing Bergen Open Research Archive by Author "Furse, Samuel Robert"

Now showing items 1-4 of 4

    • The biosynthesis of phospholipids is linked to the cell cycle in a model eukaryote 

      Vitova, Milada; Lanta, Vojtech; Cizkova, Maria; Jakubec, Martin; Rise, Frode; Halskau, Øyvind; Bisova, Katerina; Furse, Samuel Robert (Journal article; Peer reviewed, 2021)
      The structural challenges faced by eukaryotic cells through the cell cycle are key for understanding cell viability and proliferation. We tested the hypothesis that the biosynthesis of structural lipids is linked to the ...

    • Cholesterol-containing lipid nanodiscs promote an α-synuclein binding mode that accelerates oligomerization 

      Jakubec, Martin; Bariås, Espen; Furse, Samuel Robert; Govasli Larsen, Morten Andreas; George, Vinnit; Turcu, Diana Cornelia; Iashchishyn, Igor A.; Morozova-Roche, Ludmilla A.; Halskau, Øyvind (Journal article; Peer reviewed, 2021)
      Dysregulation of the biosynthesis of cholesterol and other lipids has been implicated in many neurological diseases, including Parkinson's disease. Misfolding of α-synuclein (α-Syn), the main actor in Parkinson's disease, ...

    • Detection of misfolded protein aggregates from a clinical perspective 

      Jakubec, Martin; Strømland, Øyvind; Furse, Samuel Robert; Halskau, Øyvind (Peer reviewed; Journal article, 2016)
      Neurodegenerative Protein Misfolding Diseases (PMDs), such as Alzheimer’s (AD), Parkinson’s (PD) and prion diseases, are generally difficult to diagnose before irreversible damage to the central nervous system damage has ...

    • Evidence that Listeria innocua modulates its membrane’s stored curvature elastic stress, but not fluidity, through the cell cycle 

      Furse, Samuel Robert; Jakubec, Martin; Rise, Frode; Williams, Huw E.; Rees, Catherine E.D.; Halskau, Øyvind (Peer reviewed; Journal article, 2017-08-14)
      This paper reports that the abundances of endogenous cardiolipin and phosphatidylethanolamine halve during elongation of the Gram-positive bacterium Listeria innocua. The lyotropic phase behaviour of model lipid systems ...