Browsing Bergen Open Research Archive by Author "Gerdts, Eva"
Now showing items 1-20 of 33
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Association of myocardial energetic efficiency with circumferential and longitudinal left ventricular myocardial function in subjects with increased body mass index (The FATCOR study)
Mancusi, Costantino; Midtbø, Helga Bergljot; De Luca, Nicola; Halland, Hilde; de Simone, Giovanni; Gerdts, Eva (Journal article; Peer reviewed, 2021)Lower myocardial mechanic-energetic efficiency (MEEi), expressed as stroke volume/heart rate ratio (SV/HR) in mL/s/g of the left ventricular (LV) mass, is associated with the incidence of heart failure in subjects with ... -
Biomarkers and echocardiographic predictors of myocardial dysfunction in patients with hypertension
Bielecka-Dabrowa, Agata; Michalska-Kasiczak, Marta; Gluba, Anna; Ahmed, Ali; Gerdts, Eva; von Haehling, Stephan; Rysz, Jacek; Banach, Maciej (Peer reviewed; Journal article, 2015-03-09)The study aimed to identify early echocardiographic and circulating biomarkers of heart failure (HF) in hypertensive patients with normal resting echocardiography. Echocardiography at rest and during exercise, and selected ... -
Cardiac adaptation to hypertension in adult female Dahl salt-sensitive rats is dependent on ovarian function, but loss of ovarian function does not predict early maladaptation
Ludvigsen, Stian; Mancusi, Costantino; Kildal, Simon; de Simone, Giovanni; Gerdts, Eva; Ytrehus, Kirsti (Peer reviewed; Journal article, 2018-02-08)Aim of study was to examine experimentally the adult female hypertensive heart in order to determine the role of ovary function in the response of the heart to salt‐dependent hypertension. Dahl salt‐sensitive rats, age 12 ... -
Contrast stress echocardiography in hypertensive heart disease
Lønnebakken, Mai Tone; Rieck, Åshild Elseth; Gerdts, Eva (Peer reviewed; Journal article, 2011-11-18)Hypertension is associated with atherosclerosis and cardiac and vascular structural and functional changes. Myocardial ischemia may arise in hypertension independent of coronary artery disease through an interaction between ... -
Covariables of Myocardial Function in Women and Men with Increased Body Mass Index
Pristaj, Nadia; Saeed, Sahrai; Midtbø, Helga Bergljot; Halland, Hilde; Matre, Knut; Gerdts, Eva (Journal article; Peer reviewed, 2020)Introduction Sex-difference in types of cardiac organ damage has been reported in subjects with increased body mass index (BMI). However less is known about sex-differences in left ventricular (LV) myocardial function ... -
Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations
Bergland, Ola Undrum; Halvorsen, Lene Vernås; Søraas, Camilla Lund; Hjørnholm, Ulla; Kjær, Vibeke Norheim; Rognstad, Stine; Brobak, Karl Marius; Aune, Arleen; Olsen, Eirik; Fauchald, Ylva; Heimark, Sondre; Thorstensen, Christian W; Liestøl, Knut; Solbu, Marit Dahl; Gerdts, Eva; Mo, Rune; Rostrup, Morten; Kjeldsen, Sverre; Høieggen, Aud; Opdal, Mimi Stokke; Fadl Elmula, Fadl Elmula M. (Journal article; Peer reviewed, 2021)Nonadherence to drugs is a challenge in hypertension treatment. We aimed to assess the prevalence of nonadherence by serum drug concentrations compared with 2 indirect methods and relate to the prescribed drug regimens in ... -
Early vascular aging in young and middle-aged ischemic stroke patients: The Norwegian stroke in the young study
Saeed, Sahrai; Waje-Andreassen, Ulrike; Fromm, Annette; Øygarden, Halvor; Kokorina, Marina Victorovna; Næss, Halvor; Gerdts, Eva (Peer reviewed; Journal article, 2014-11-18)Background: Ischemic stroke survivors have high risk of cardiovascular morbidity and mortality even at young age, suggesting that early arterial aging is common among such patients. Methods: We measured aortic stiffness ... -
Factors associated with increase in blood pressure and incident hypertension in early midlife: the Hordaland Health Study
Kringeland, Ester Anne; Tell, Grethe S.; Midtbø, Helga Bergljot; Haugsgjerd, Teresa Risan; Igland, Jannicke; Gerdts, Eva (Journal article; Peer reviewed, 2020)Purpose: We aimed to identify sex-specific factors associated with increase in blood pressure (BP) and incident hypertension in early midlife. Materials and methods: 2,008 women and 1,610 men aged 40-43 years were ... -
Giant right ventricular outflow tract thrombus in hereditary spherocytosis: a case report
Davidsen, Cedric; Larsen, Terje H.; Gerdts, Eva; Lønnebakken, Mai Tone (Peer reviewed; Journal article, 2016-04-26)Background: In hereditary spherocytosis with severe anemia, splenectomy is a recommended treatment. However, the spleen carries an important role both in immune function and coagulation. The increased risk of bacterial ... -
Global coronary artery plaque area is associated with myocardial hypoperfusion in women with non-ST elevation myocardial infarction
Eskerud, Ingeborg; Gerdts, Eva; Nordrehaug, Jan Erik; Lønnebakken, Mai Tone (Peer reviewed; Journal article, 2015-05)Background: Women with non-ST elevation myocardial infarction (NSTEMI) have similar extent of myocardial ischemia but less obstructive coronary artery disease (CAD) than their male counterparts. We tested the impact of ... -
Global left ventricular load in asymptomatic aortic stenosis: covariates and prognostic implication (the SEAS trial)
Rieck, Åshild Elseth; Gerdts, Eva; Lønnebakken, Mai Tone; Bahlmann, Edda; Cioffi, Giovanni; Gohlke-Bärwolf, Christa; Ray, Simon; Cramariuc, Dana (Peer reviewed; Journal article, 2012-11-05)Introduction: Valvuloarterial impedance (Zva) is a measure of global (combined valvular and arterial) load opposing left ventricular (LV) ejection in aortic stenosis (AS). The present study identified covariates and tested ... -
Heart Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 Gene Expression Associated With Male Sex and Salt-Sensitive Hypertension in the Dahl Rat
Ytrehus, Kirsti; Gerdts, Eva; Mancusi, Costatino; de Simone, Giovanni; Ludvigsen, Stian (Journal article; Peer reviewed, 2021)Angiotensin-converting enzyme 2 (ACE 2) in the heart including its sex dependency in the hypertensive heart, has not been much studied compared to ACE. In the present study, we used the Dahl salt-sensitive rat exposed to ... -
Hypertension in women: Should there be a sex-specific threshold?
Gerdts, Eva; de Simone, Giovanni (Journal article; Peer reviewed, 2021)Conventionally, hypertension is defined by the same blood pressure (BP) threshold (systolic BP ≥140 and/or diastolic BP ≥90 mmHg) in both women and men. Several studies have documented that women with hypertension are more ... -
Impact of aortic stiffness on myocardial ischaemia in non-obstructive coronary artery disease
Lønnebakken, Mai Tone; Eskerud, Ingeborg; Larsen, Terje H; Midtbø, Helga Bergljot; Kokorina, Marina Victorovna; Gerdts, Eva (Peer reviewed; Journal article, 2019)Objective: High aortic stiffness may reduce myocardial perfusion pressure and contribute to development of myocardial ischaemia. Whether high aortic stiffness is associated with myocardial ischaemia in patients with stable ... -
Impact of arterio–ventricular interaction on first-phase ejection fraction in aortic stenosis
Einarsen, Eigir; Hjertaas, Johannes; Gu, Haotian; Matre, Knut; Chowienczyk, Philip J.; Gerdts, Eva; Chambers, John B.; Saeed, Sahrai (Peer reviewed; Journal article, 2020)Aims: First-phase ejection fraction (EF1), the EF at the time to peak aortic jet velocity, has been proposed as a novel marker of peak systolic function in aortic stenosis (AS). This study aimed to explore the association ... -
Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: Position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart
Perrino, Cinzia; Ferdinandy, Péter; Bøtker, Hans Erik; Brundel, Bianca J. J. M; Collins, Peter; Davidson, Sean M; Den Ruijter, Hester M.; Engel, Felix B.; Gerdts, Eva; Girao, Henrique; Gyöngyösi, Mariann; Hausenloy, Derek J.; Lecour, Sandrine; Madonna, Rosalinda; Marber, Michael; Murphy, Elizabeth; Pesce, Maurizio; Regitz-Zagrosek, Vera; Sluijter, Joost P.G.; Steffens, Sabine; Gollmann-Tepeköylü, Can; Van Laake, Linda W.; Van Linthout, Sophie; Schulz, Rainer; Ytrehus, Kirsti (Journal article; Peer reviewed, 2021)Ischaemic heart disease (IHD) is a complex disorder and a leading cause of death and morbidity in both men and women. Sex, however, affects several aspects of IHD, including pathophysiology, incidence, clinical presentation, ... -
Left ventricular hypertrophy contributes to Myocardial Ischemia in Non-obstructive Coronary Artery Disease (the MicroCAD study)
Eskerud, Ingeborg; Gerdts, Eva; Larsen, Terje H; Lønnebakken, Mai Tone (Peer reviewed; Journal article, 2019)Background: The underlying mechanisms causing myocardial ischemia in non-obstructive coronary artery disease (CAD) are still unclear. We explored whether left ventricular hypertrophy (LVH) was associated with myocardial ... -
Long-term blood pressure trajectories and incident atrial fibrillation in women and men: the Tromsø Study
Sharashova, Ekaterina; Wilsgaard, Tom; Ball, Jocasta; Morseth, Bente; Gerdts, Eva; Hopstock, Laila Arnesdatter; Mathiesen, Ellisiv B.; Schirmer, Henrik; Løchen, Maja-Lisa (Peer reviewed; Journal article, 2019)Aims: To explore sex-specific associations between long-term individual blood pressure (BP) patterns and risk of incident atrial fibrillation (AF) in the general population. Methods and results: Blood pressure was measured ... -
Low myocardial energetic efficiency is associated with increased mortality in aortic stenosis
Bahlmann, Edda; Einarsen, Eigir; Cramariuc, Dana; Midtbø, Helga Bergljot; Mancusi, Costatino; Rossebø, Anne Bjørhovde; Willems, Stephan; Gerdts, Eva (Journal article; Peer reviewed, 2021)Objectives In hypertension, low myocardial energetic efficiency (MEEi) has been documented as an integrated marker of metabolic and left ventricular (LV) myocardial dysfunction. We tested the predictive performance of MEEi ... -
Markers of Subclinical Atherosclerosis in Severe Obesity and One Year after Bariatric Surgery
Kovac, Nina; Grymyr, Lisa Marie Dale; Gerdts, Eva; Nadirpour, Saied; Nedrebø, Bjørn Gunnar; Hjertaas, Johannes Just; Matre, Knut; Cramariuc, Dana (Journal article; Peer reviewed, 2022)Background: Aortic valve sclerosis (AVS), mitral valve sclerosis (MVS), remodeling of major arteries, and increased pericardial fat are associated with subclinical atherosclerosis. We assessed these markers of atherosclerosis ...