• Alcohol‐attributed disease burden in four Nordic countries between 2000 and 2017: Are the gender gap s narrowing? A comparison using the Global Burden of Disease, Injury and Risk Factor 2017 study 

      Agardh, Emilie, E.; Allebeck, Peter; Flodin, Pär; Wenneberg, Peter; Ramstedt, Mats; Knudsen, Ann Kristin; Øverland, Simon Nygaard; Kinge, Jonas Minet; Tollånes, Mette C.; Eikemo, Terje Andreas; Skogen, Jens Christoffer; Mäkelä, Pia; Gissler, Mika; Juel, Knud; Iburg, Kim Moesgaard; McGrath, John J.; Naghavi, Mohsen; Vollset, Stein Emil; Gakidou, Emmanuela; Danielsson, Anna-Karin (Journal article; Peer reviewed, 2020)
      Introduction and Aims The gender difference in alcohol use seems to have narrowed in the Nordic countries, but it is not clear to what extent this may have affected differences in levels of harm. We compared gender ...
    • Alcohol‐attributed disease burden in four Nordic countries between 2000 and 2017: Are the gender gaps narrowing? A comparison using the Global Burden of Disease, Injury and Risk Factor 2017 study 

      Agardh, Emilie, E.; Allebeck, Peter; Flodin, Pär; Wenneberg, Peter; Ramstedt, Mats; Knudsen, Ann Kristin; Øverland, Simon Nygaard; Kinge, Jonas Minet; Tollånes, Mette C.; Eikemo, Terje Andreas; Skogen, Jens Christoffer; Mäkelä, Pia; Gissler, Mika; Juel, Knud; Iburg, Kim Moesgaard; McGrath, John J.; Naghavi, Mohsen; Vollset, Stein Emil; Gakidou, Emmanuela; Danielsson, Anna-Karin (Journal article; Peer reviewed, 2021)
      Introduction and Aims The gender difference in alcohol use seems to have narrowed in the Nordic countries, but it is not clear to what extent this may have affected differences in levels of harm. We compared gender ...
    • Antipsychotic drug use in pregnancy: A multinational study from ten countries 

      Reutfors, Johan; Cesta, Carolyn; Cohen, Jacqueline Mallory; Bateman, Brian T; Brauer, Ruth; Einarsdottir, Kristjana; Engeland, Anders; Furu, Kari; Gissler, Mika; Havard, Alys; Hernandez-Diaz, Sonia; Huybrechts, Krista F.; Karlstad, Øystein; Leinonen, Maarit; Li, Jiong; Man, Kenneth K. C.; Pazzagli, Laura; Schaffer, Andrea; Schink, Tania; Wang, Zixuan; Yu, Yongfu; Zoega, Helga; Bröms, Gabriella (Journal article; Peer reviewed, 2020)
      Aim To compare the prevalence and trends of antipsychotic drug use during pregnancy between countries across four continents. Methods Individually linked health data in Denmark (2000−2012), Finland (2005–2014), Iceland ...
    • Antipsychotic use in pregnancy and risk of attention/ deficit-hyperactivity disorder and autism spectrum disorder: a Nordic cohort study 

      Halfdanarson, Oskar; Cohen, Jacqueline Mallory; Karlstad, Øystein; Cesta, Carolyn E.; Bjørk, Marte-Helene; Håberg, Siri Eldevik; Einarsdottir, Kristjana; Furu, Kari; Gissler, Mika; Hjellvik, Vidar; Kieler, Helle; Leinonen, Maarit; Nørgaard, Mette; Essen, Buket Öztürk; Ulrichsen, Sinna Pilgaard; Reutfors, Johan; Zoega, Helga (Journal article; Peer reviewed, 2021)
      Background Antipsychotics are increasingly used among women of childbearing age and during pregnancy. Objective To determine whether children exposed to antipsychotics in utero are at increased risk of attention-d ...
    • Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability 

      Bjørk, Marte-Helene; Zoega, Helga; Leinonen, Maarit K.; Cohen, Jacqueline Mallory; Dreier, Julie Werenberg; Furu, Kari; Gilhus, Nils Erik; Gissler, Mika; Halfdanarson, Oskar; Igland, Jannicke; Sun, Yuelian; Tomson, Torbjörn; Alvestad, Silje; Christensen, Jakob (Journal article; Peer reviewed, 2022)
      Importance: Women with epilepsy frequently need antiseizure medication (ASM) to prevent seizures in pregnancy. Risk of neurodevelopmental disorders after prenatal exposure to AMSs is uncertain. Objective: To determine ...
    • Associations of pregnancy-related factors and birth characteristics with risk of endometrial cancer: A Nordic population-based case-control study 

      Trabert, Britton; Troisi, Rebecca; Grotmol, Tom; Ekbom, Anders; Engeland, Anders; Gissler, Mika; Glimelius, Ingrid; Madanat-Harjuoja, Laura M.; Sørensen, Henrik Toft; Tretli, Steinar; Ording, Anne Gulbech; Bjørge, Tone (Peer reviewed; Journal article, 2020)
      Many pregnancy‐related factors are associated with reduced endometrial cancer risk. However, it remains unclear whether pregnancy‐related complications (e.g., hypertensive conditions) are associated with risk and whether ...
    • The burden of disease for children born alive with Turner syndrome—A European cohort study 

      Andersen, Ann-Louise Rud; Urhoj, Stine Kjaer; Tan, Joachim; Cavero-Carbonell, Clara; Gatt, Miriam; Gissler, Mika; Klungsøyr, Kari; Khoshnood, Babak; Morris, Joan; Neville, Amanda J.; Pierini, Anna; Scanlon, Ieuan; de Walle, Hermien E. K.; Wellesley, Diana; Garne, Ester; Loane, Maria (Journal article; Peer reviewed, 2023)
      Background Turner syndrome is a rare congenital anomaly caused by complete or partial X chromosome monosomy that may affect mortality and morbidity in childhood. Methods This population-based data-linkage cohort study, ...
    • Cancer risk in children of mothers with epilepsy and high-dose folic acid use during pregnancy 

      Vegrim, Håkon Magne; Dreier, Julie Werenberg; Alvestad, Silje; Gilhus, Nils Erik; Gissler, Mika; Igland, Jannicke; Leinonen, Maarit; Tomson, Torbjörn; Sun, Yuelian; Zoega, Helga; Christensen, Jakob; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)
      Importance Women with epilepsy are recommended high doses of folic acid before and during pregnancy owing to risk of congenital anomalies associated with antiseizure medications. Whether prenatal exposure to high-dose ...
    • Cancer risk in individuals with major birth defects: large Nordic population based case-control study among children, adolescents, and adults 

      Daltveit, Dagrun Slettebø; Klungsøyr, Kari; Engeland, Anders; Ekbom, Anders; Gissler, Mika; Glimelius, Ingrid; Grotmol, Tom; Madanat-Harjuoja, Laura M.; Ording, Anne Gulbech; Sæther, Solbjørg Makalani Myrtveit; Sørensen, Henrik Toft; Troisi, Rebecca; Bjørge, Tone (Journal article; Peer reviewed, 2020)
      Objective To examine associations between birth defects and cancer from birth into adulthood. Design Population based nested case-control study. Setting Nationwide health registries in Denmark, Finland, Norway, ...
    • Clarity and consistency in stillbirth reporting in Europe: why is it so hard to get this right? 

      Gissler, Mika; Durox, Mélanie; Smith, Lucy; Blondel, Béatrice; Broeders, Lisa; Hindori-Mohangoo, Ashna D.; Kearns, Karen; Kolarova, Rumyana; Loghi, Marzia; Rodin, Urelija; Szamotulska, Katarzyna; Velebil, Petr; Zurriaga, Oscar; Zeitlin, Jennifer; Klungsøyr, Kari (Journal article; Peer reviewed, 2022)
      Background Stillbirth is a major public health problem, but measurement remains a challenge even in high-income countries. We compared routine stillbirth statistics in Europe reported by Eurostat with data from the ...
    • Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations 

      Cohen, Jacqueline Mallory; Alvestad, Silje; Cesta, Carolyn E.; Bjørk, Marte-Helene; Leinonen, Maarit; Nørgaard, Mette; Einarsdóttir, Kristjana; Engeland, Anders; Gissler, Mika; Karlstad, Øystein; Klungsøyr, Kari; Odsbu, Ingvild; Reutfors, Johan; Selmer, Randi Marie; Tomson, Torbjörn; Ulrichsen, Sinna Pilgaard; Zoega, Helga; Furu, Kari (Journal article; Peer reviewed, 2022)
      Objective: This study was undertaken to examine the comparative safety of antiseizure medication (ASM) monotherapy in pregnancy with respect to risk of major congenital malformations (MCMs), overall and by MCM subtype. ...
    • COVID-19 in pregnancy—characteristics and outcomes of pregnant women admitted to hospital because of SARS-CoV-2 infection in the Nordic countries 

      Engjom, Hilde Marie; Aabakke, Anna J. M.; Klungsøyr, Kari; Svanvik, Teresia; Äyräs, Outi; Jonasdottir, Eva; Thurn, Lars; Jones, Elin; Pettersson, Karin; Nyfløt, Lill Trine; Al-Zirqi, Iqbal Ahmad Abdelwahab; Vangen, Siri; Juliusson, Pétur Benedikt; Källén, Karin; Gissler, Mika; Krebs, Lone (Journal article; Peer reviewed, 2021)
      Introduction Population-based studies about the consequences of SARS-CoV-2 infection (COVID-19) in pregnancy are few and have limited generalizability to the Nordic population and healthcare systems. Material and ...
    • Determinants of long-term unemployment in early adulthood: A Finnish birth cohort study 

      Lallukka, Tea; Kerkelä, Martta; Ristikari, Tiina; Merikukka, Marko; Hiilamo, Heikki; Virtanen, Marianna; Øverland, Simon Nygaard; Gissler, Mika; Halonen, Jaana I (Peer reviewed; Journal article, 2019-08)
      Cumulative contributions of social and health-related determinants to long-term unemployment during early working life among young adults are poorly understood. Therefore, we used four cumulative indices of both parental ...
    • Differences in perinatal and infant mortality in high-income countries: Artifacts of birth registration or evidence of true differences? 

      Deb-Rinker, Paromita; León, Juan Andrés; Gilbert, Nicolas L.; Rouleau, Jocelyn; Andersen, Anne-Marie Nybo; Bjarnadóttir, Ragnheiður I.; Gissler, Mika; Mortensen, Laust H.; Skjaerven, Rolv; Vollset, Stein Emil; Zhang, Xun; Shah, Prakesh S.; Sauve, Reg S.; Kramer, Michael S.; Joseph, K.S. (Peer reviewed; Journal article, 2015-09-04)
      Background: Variation in birth registration criteria may compromise international comparisons of fetal and infant mortality. We examined the effect of birth registration practices on fetal and infant mortality rates to ...
    • Disease Burden Attributed to Drug use in the Nordic Countries: a Systematic Analysis for the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 

      Agardh, Emilie, E.; Allebeck, Peter; Knudsen, Ann Kristin Skrindo; Aronsson, Emma Amanda; Flodin, Pär; Eikemo, Terje Andreas; Bangah, Paul R.; Skogen, Jens Christoffer; Gissler, Mika; Rönkä, Sanna; McGrath, John J.; Sigurvinsdottir, Rannveig; Dadras, Omid; Deuba, Keshab; Hedna, Khedidja; Mentis, Alexios‑Fotios A.; Sagoe, Dominic; Shiri, Rahman; Weye, Nanna Ørslev; Hay, Simon I.; Murray, Christopher J. L.; Naghavi, Mohsen; Pasovic, Maja; Vos, Theo; Wennberg, Peter; Danielsson, Anna‑Karin (Journal article; Peer reviewed, 2023)
      The Nordic countries share similarities in many social and welfare domains, but drug policies have varied over time and between countries. We wanted to compare differences in mortality and disease burden attributed to drug ...
    • Folic Acid and Risk of Preterm Birth, Preeclampsia, and Fetal Growth Restriction Among Women With Epilepsy A Prospective Cohort Study 

      Alvestad, Silje; Husebye, Elisabeth Synnøve Nilsen; Christensen, Jakob; Dreier, Julie Werenberg; Sun, Yuelian; Igland, Jannicke; Leinonen, Maarit; Gissler, Mika; Gilhus, Nils Erik; Tomson, Torbjörn; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)
      Background and Objectives Women with epilepsy treated with antiseizure medication (ASM) have increased risk of pregnancy complications including preterm birth, fetal growth restriction, and preeclampsia. We aimed to ...
    • An international contrast of rates of placental abruption: An age-period-cohort analysis 

      Ananth, Cande V.; Keyes, Katherine M.; Hamilton, Ava; Gissler, Mika; Wu, Chunsen; Liu, Shiliang; Luque-Fernandez, Miguel Angel; Skjaerven, Rolv; Williams, Michelle A.; Tikkanen, Minna; Cnattingius, Sven (Peer reviewed; Journal article, 2015-05-27)
      Background: Although rare, placental abruption is implicated in disproportionately high rates of perinatal morbidity and mortality. Understanding geographic and temporal variations may provide insights into possible amenable ...
    • International versus national growth charts for identifying small and large-for-gestational age newborns: A population-based study in 15 European countries 

      Hocquette, Alice; Durox, Mélanie; Wood, Rachael; Klungsøyr, Kari; Szamotulska, Katarzyna; Berrut, Sylvan; Rihs, Tonia; Kyprianou, Theopisti; Sakkeus, Luule; Lecomte, Aline; Zile, Irisa; Alexander, Sophie; Klimont, Jeannette; Barros, Henrique; Gatt, Miriam; Isakova, Jelena; Blondel, Béatrice; Gissler, Mika; Zeitlin, Jennifer (Journal article; Peer reviewed, 2021)
      Background To inform the on-going debate about the use of universal prescriptive versus national intrauterine growth charts, we compared perinatal mortality for small and large-for-gestational-age (SGA/LGA) infants according ...
    • Life expectancy and disease burden in the Nordic countries: results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 

      Kisa, Adnan; Knudsen, Ann Kristin; Allebeck, Peter; Tollånes, Mette Christophersen; Skogen, Jens Christoffer; Iburg, Kim Moesgaard; McGrath, John J; Juel, Knud; Agardh, Emilie Elisabet; Arnlöv, Johan; Bjørge, Tone; Carrero, Juan J.; Cederroth, Christopher R; Eggen, Anne Elise; El-Khatib, Ziad; Lycke Ellingsen, Christian; Fereshtehnejad, Seyed-Mohammad; Gissler, Mika; Hadkhale, Kishor; Havmoeller, Rasmus; Johansson, Lars; Juliusson, Petur Benedikt; Kiadaliri, Aliasghar A.; Kisa, Sezer; Lallukka, Tea; Mekonnen, Teferi; Meretoja, Tuomo J.; Meretoja, Atte; Naghavi, Mohsen; Neupane, Subas; Nguyen, Truc Trung; Petzold, Max; Plana-Ripoll, Oleguer; Shiri, Rahman; Sigurvinsdottir, Rannveig; Skirbekk, Vegard; Skou, Søren T; Sigfusdottir, Inga Dora; Steiner, Timothy J.; Sulo, Gerhard; Truelsen, Thomas Clement; Vasankari, Tommi Juhani; Weiderpass, Elisabete; Vollset, Stein Emil; Vos, Theo; Øverland, Simon (Peer reviewed; Journal article, 2019-12-01)
      Background The Nordic countries have commonalities in gender equality, economy, welfare, and health care, but differ in culture and lifestyle, which might create country-wise health differences. This study compared life ...
    • Nordic health registry-based research: A review of health care systems and key registries 

      Laugesen, Kristina; Ludvigsson, Jonas F.; Schmidt, Morten; Gissler, Mika; Valdimarsdottir, Unnur; Lunde, Astrid; Sørensen, Henrik Toft (Journal article; Peer reviewed, 2021)
      The Nordic countries are Denmark, Finland, Iceland, Norway, and Sweden and comprise a total population of approximately 27 million. The countries provide unique opportunities for joint health registry-based research in ...