Browsing Bergen Open Research Archive by Author "Glastad, Robert Clay"

Now showing items 1-4 of 4

    • Avoiding organelle mutational meltdown across eukaryotes with or without a germline bottleneck 

      Edwards, David; Røyrvik, Ellen Christine; Chustecki, Joanne; Giannakis, Konstantinos; Glastad, Robert Clay; Radzvilavicius, Arunas; Johnston, Iain (Journal article; Peer reviewed, 2021)
      Mitochondrial DNA (mtDNA) and plastid DNA (ptDNA) encode vital bioenergetic apparatus, and mutations in these organelle DNA (oDNA) molecules can be devastating. In the germline of several animals, a genetic “bottleneck” ...

    • \lambda Polarization in Heavy Ion Collisions 

      Glastad, Robert Clay (Master thesis, 2015-06-02)
      Results on transverse lambda polarization in peripheral heavy ion collisions in an exact, analytic, self-similar rotating hydrodynamics model using the gradient and curl of the inverse temperature field. We estimate the ...

    • Metabolic role of the hepatic valine/3-hydroxyisobutyrate (3-HIB) pathway in fatty liver disease 

      Bjune, Mona Synnøve; Dyer, Laurence; Laupsa-Borge, Johnny; Sommersten, Cathrine Horn; McCann, Adrian; Glastad, Robert Clay; Johnston, Iain; Kern, Matthias; Blüher, Matthias; Mellgren, Gunnar; Dankel, Simon N (Journal article; Peer reviewed, 2023)
      Background: The valine (branched-chain amino acid) metabolite 3-hydroxyisobutyrate (3-HIB), produced by 3-Hydroxyisobutyryl-CoA Hydrolase (HIBCH), is associated with insulin resistance and type 2 diabetes, but implicated ...

    • Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions 

      Glastad, Robert Clay; Johnston, Iain (Journal article; Peer reviewed, 2023)
      Mitochondria are highly dynamic organelles, containing vital populations of mitochondrial DNA (mtDNA) distributed throughout the cell. Mitochondria form diverse physical structures in different cells, from cell-wide ...