Browsing Bergen Open Research Archive by Author "Goncearenco, Alexander"

Now showing items 1-4 of 4

    • Exploring the evolution of protein function in Archaea 

      Goncearenco, Alexander; Berezovsky, Igor N. (Peer reviewed; Journal article, 2012-05-30)
      Background: Despite recent progress in studies of the evolution of protein function, the questions what were the first functional protein domains and what were their basic building blocks remain unresolved. Previously, we ...

    • Highlights from the Eighth International Society for Computational Biology (ISCB) Student Council Symposium 2012 

      Goncearenco, Alexander; Grynberg, Priscila; Botvinnik, Olga B.; Macintyre, Geoff; Abeel, Thomas (Peer reviewed; Journal article, 2012-12-14)
      Abstract The report summarizes the scientific content of the annual symposium organized by the Student Council of the International Society for Computational Biology (ISCB) held in conjunction with the Intelligent Systems ...

    • Molecular mechanisms of adaptation emerging from the physics and evolution of nucleic acids and proteins 

      Goncearenco, Alexander; Ma, Binguang; Berezovsky, Igor (Peer reviewed; Journal article, 2014)
      DNA, RNA and proteins are major biological macromolecules that coevolve and adapt to environments as components of one highly interconnected system. We explore here sequence/structure determinants of mechanisms of adaptation ...

    • SPACER: server for predicting allosteric communication and effects of regulation 

      Goncearenco, Alexander; Mitternacht, Simon; Yong, Taipang; Eisenhaber, Birgit; Eisenhaber, Frank; Berezovsky, Igor (Peer reviewed; Journal article, 2013-06-03)
      The SPACER server provides an interactive framework for exploring allosteric communication in proteins with different sizes, degrees of oligomerization and function. SPACER uses recently developed theoretical concepts based ...