• Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling 

      Pettersen, Kristine; Andersen, Sonja Benedikte; Degen, simone; Tadini, Valentina; Grosjean, Joel; Hatakeyama, Shinji; Tesfahun, Almaz Nigatu; Moestue, Siver Andreas; Kim, Jana; Nonstad, Unni; Romundstad, Pål Richard; Skorpen, Frank; Sørhaug, Sveinung; Amundsen, Tore; Grønberg, Bjørn Henning; Strasser, Florian; Stephens, Nathan; Hoem, Dag; Molven, Anders; Kaasa, Stein; Fearon, Kenneth; Jacobi, Carsten; Bjørkøy, Geir (Peer reviewed; Journal article, 2017-05-17)
      The majority of cancer patients with advanced disease experience weight loss, including loss of lean body mass. Severe weight loss is characteristic for cancer cachexia, a condition that significantly impairs functional ...
    • Case Report: Limbic encephalitis following treatment with durvalumab for small-cell lung cancer 

      Moss, Thomas Totland; Stavem, Knut; Aandahl, Astrid; Gløersen, Anne S.; Grønberg, Bjørn Henning; Neumann, Kirill; Vedeler, Christian Alexander; Lundqvist, Christofer (Journal article; Peer reviewed, 2023-10-16)
      Background: Durvalumab is an immune checkpoint Inhibitor (ICIs) that is used in the treatment of malignant tumors, such as lung cancer and melanoma. ICIs are associated with immune-related adverse events including autoimmune ...
    • Geriatric assessment with management for older patients with cancer receiving radiotherapy. Protocol of a Norwegian cluster-randomised controlled pilot study 

      Røyset, Inga Marie; Saltvedt, Ingvild; Rostoft, Siri; Grønberg, Bjørn Henning; Kirkevold, Øyvind; Oldervoll, Line Merethe; Bye, Asta; Saltyte Benth, Jurate; Bergh, Sverre; Melby, Line; Halsteinli, Vidar; Døhl, Øystein; Røsstad, Tove Garåsen; Eriksen, Guro Falk; Sollid, May Ingvild Volungholen; Rolfson, Darryl; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2021)
      About 50% of patients with cancer are expected to need radiotherapy (RT), and the majority of these are older. To improve outcomes for older patients with cancer, geriatric assessment (GA) with management (GAM) is highly ...
    • Geriatric assessment with management for older patients with cancer receiving radiotherapy: a cluster-randomised controlled pilot study 

      Jordhøy, Marit Slaaen; Røyset, Inga Marie; Saltvedt, Ingvild Tina; Grønberg, Bjørn Henning; Halsteinli, Vidar; Døhl, Øystein; Vossius, Corinna Elisabeth; Kirkevold, Øyvind; Bergh, Sverre; Rostoft, Siri; Oldervoll, Line Merethe; Bye, Asta; Melby, Line Kari; Røsstad, Tove Garåsen; Eriksen, Guro Falk; Sollid, May Ingvild Volungholen; Rolfson, Darryl; Saltyte Benth, Jurate (Journal article; Peer reviewed, 2024)
      Background: Geriatric assessment and management (GAM) improve outcomes in older patients with cancer treated with surgery or chemotherapy. It is unclear whether GAM may provide better function and quality of life (QoL), ...
    • Geriatric impairments are associated with reduced quality of life and physical function in older patients with cancer receiving radiotherapy - A prospective observational study 

      Eriksen, Guro Falk; Saltyte Benth, Jurate; Grønberg, Bjørn Henning; Rostoft, Siri; Kirkhus, Lene; Kirkevold, Øyvind; Oldervoll, Line Merethe; Bye, Asta; Hjelstuen, Anne Kristine; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2023)
      Introduction: Quality of life (QoL) and function are important outcomes for older adults with cancer. We aimed to assess differences in trends in patient-reported outcomes (PROs) during radiotherapy (RT) between (1) groups ...
    • Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway 

      Helland, Åslaug; Russnes, Hege Elisabeth Giercksky; Fagereng, Gro Live; Al-Shibli, Khalid Ibrahim; Andersson, Yvonne; Berg, Thomas; Bjørge, Line; Blix, Egil Støre; Bjerkehagen, Bodil; Brabrand, Sigmund; Dalhaug, Astrid; Dietzel, Dalia; Dønnem, Tom; Enerly, Espen; Flobak, Åsmund; Fluge, Sverre; Gilje, Bjørnar; Gjertsen, Bjørn Tore; Grønberg, Bjørn Henning; Grønås, Kari; Guren, Tormod Kyrre; Hamre, Hanne Mari; Haug, Åse; Heinrich, Daniel; Hjortland, Geir Olav; Hovig, Eivind; Hovland, Randi; Iversen, Ann-Charlotte; Janssen, Emiel; Kyte, Jon A; Gythfeldt, Hedda; Lothe, Ragnhild Adelheid; Lund, Jo-Åsmund; Meza, Leonardo Zepeda; Munthe-Kaas, Monica Cheng; Nguyen, Olav Toai Duc; Niehusmann, Pitt; Nilsen, Hilde; Puco, Katarina; Ree, Anne Hansen; Riste, Tonje Bøyum; Semb, Karin; Steinskog, Eli Sihn Samdal; Stensvold, Andreas; Suhrke, Pål; Tennøe, Øyvind Krohn; Tjønnfjord, Geir Erland; Vassbotn, Liv Jorunn; Aas, Eline; Aasebø, Kristine Øverås; Tasken, Kjetil; Smeland, Sigbjørn; Cameron, Marte Grønlie (Journal article; Peer reviewed, 2022)
      Background Matching treatment based on tumour molecular characteristics has revolutionized the treatment of some cancers and has given hope to many patients. Although personalized cancer care is an old concept, renewed ...
    • Liquid Biopsies in Solid Cancers: Implementation in a Nordic Healthcare System 

      Nordgård, Oddmund; Forthun, Rakel Brendsdal; Lapin, Morten; Grønberg, Bjørn Henning; Kalland, Karl Henning; Kopperud, Reidun Kristin; Thomsen, Liv Cecilie Vestrheim; Tjensvoll, Kjersti; Gilje, Bjørnar; Gjertsen, Bjørn Tore; Hovland, Randi (Journal article; Peer reviewed, 2021)
      Liquid biopsies have emerged as a potential new diagnostic tool, providing detailed information relevant for characterization and treatment of solid cancers. We here present an overview of current evidence supporting the ...
    • Self-reported health, function, and use of health care services in older prostate cancer survivors compared to matched controls: a cross-sectional study 

      Sletten, Reidun; Jordhøy, Marit Slaaen; Oldervoll, Line Merethe; Skjellegrind, Håvard Kjesbu; Saltyte Benth, Jurate; Åstrøm, Lennart; Kirkevold, Øyvind; Bergh, Sverre; Grønberg, Bjørn Henning; Rostoft, Siri; Bye, Asta; Mork, Paul Jarle; Christiansen, Ola (Journal article; Peer reviewed, 2024)
      Purpose Information about outcomes of particular relevance to older prostate cancer survivors is limited. This study aimed to compare health, activities of daily living (ADL), and use of health care services between ...
    • Small Cell Lung Cancer in Norway: Patterns of Care by Health Region and Survival Trends 

      Nilssen, Yngvar; Brustugun, Odd Terje; Fjellbirkeland, Lars; Grønberg, Bjørn Henning; Haram, Per Magnus; Helbekkmo, Nina; Helland, Åslaug; Wahl, Sissel Gyrid Freim; Aanerud, Marianne; Solberg, Steinar (Journal article; Peer reviewed, 2024)
      Introduction/Background There has been a marked survival improvement for patients with non–small-cell lung cancer. We describe the national trends in characteristics and survival, and geographical differences in diagnostic ...
    • Vinorelbine and gemcitabine vs vinorelbine and carboplatin as first-line treatment of advanced NSCLC. A phase III randomised controlled trial by the Norwegian Lung Cancer Study Group 

      Fløtten, Øystein; Grønberg, Bjørn Henning; Bremnes, Roy M.; Amundsen, Tore; Sundstrøm, Stein Harald; Rolke, Heidi; Hornslien, Kjersti; Wentzel-Larsen, Tore; Aasebø, Ulf; von Plessen, Christian (Journal article; Peer reviewed, 2012)
      Background: Platinum-based doublet chemotherapy is the standard first-line treatment for advanced non-small cell lung cancer (NSCLC), but earlier studies have suggested that non-platinum combinations are equally effective ...