Blar i Bergen Open Research Archive på forfatter "Grewal, Harleen M. S."
-
CD4 lymphocyte dynamics in Tanzanian pulmonary tuberculosis patients with and without hiv co-infection
Andersen, Aase B.; Range, Nyagosya S.; Changalucha, John; PrayGod, George; Kidola, Jeremiah; Grewal, Harleen M. S.; Faurholt-Jepsen, Daniel; Krarup, Henrik; Friis, Henrik (Peer reviewed; Journal article, 2012-03-21)Background: The interaction of HIV and tuberculosis (TB) on CD4 levels over time is complex and has been divergently reported. Methods: CD4 counts were assessed from time of diagnosis till the end of TB treatment in a ... -
Effect of Ascaris Lumbricoides specific IgE ontuberculin skin test responses in children in a high-burdensetting: a cross-sectional community-based study
van Soelen, Nelda; Mandalakas, Anna M; Kirchner, H Lester; Walzl, Gerhard; Grewal, Harleen M. S.; Jacobsen, Marc; Hesseling, Anneke C. (Peer reviewed; Journal article, 2012-09-11)Background: M.tuberculosis (M.tb) is associated with enhanced T helper cell type 1 (Th1) immune responses while helminth infection is associated with T helper cell type 2 (Th2) immune responses. Our aim was to investigate ... -
How participatory is parental consent in low literacy rural settings in low income countries? Lessons learned from a community based study of infants in South India
Rajaraman, Divya; Jesuraj, Nelson; Geiter, Lawrence; Bennett, Sean; Grewal, Harleen M. S.; Vaz, Mario; TB Trials Study Group (Peer reviewed; Journal article, 2011-02-15)Background A requisite for ethical human subjects research is that participation should be informed and voluntary. Participation during the informed consent process by way of asking questions is an indicator of the extent ... -
Increased level of acute phase reactants in patients infected with modern Mycobacterium tuberculosis genotypes in Mwanza, Tanzania
Stavrum, Ruth; PrayGod, George; Range, Nyagosya S.; Faurholt-Jepsen, Daniel; Jeremiah, Kidola; Faurholt-Jepsen, Maria; Krarup, Henrik; Aabye, Martine G.; Changalucha, John; Friis, Henrik; Andersen, Aase B.; Grewal, Harleen M. S. (Peer reviewed; Journal article, 2014-06-05)Background: There is increasing evidence to suggest that different Mycobacterium tuberculosis lineages cause variations in the clinical presentation of tuberculosis (TB). Certain M. tuberculosis genotypes/lineages have ... -
Modulation of Transcriptional and Inflammatory Responses in Murine Macrophages by the Mycobacterium tuberculosis Mammalian Cell Entry (Mce) 1 Complex
Stavrum, Ruth; Stavrum, Anne-Kristin; Valvatne, Håvard; Riley, Lee W.; Ulvestad, Elling; Jonassen, Inge; Assmus, Jørg; Doherty, Tanya Mark; Grewal, Harleen M. S. (Peer reviewed; Journal article, 2011-10-24)The outcome of many infections depends on the initial interactions between agent and host. Aiming at elucidating the effect of the M. tuberculosis Mce1 protein complex on host transcriptional and immunological responses ... -
The tuberculin skin test in school going adolescents in South India: associations of socio-demographic and clinical characteristics with TST positivity and non-response
Uppada, Dharma Rao; Selvam, Sumithra; Jesuraj, Nelson; Bennett, Sean; Verver, Suzanne; Grewal, Harleen M. S.; Vaz, Mario; TB Trials Study Group (Peer reviewed; Journal article, 2014-11-18)Background: India has generally used 1 TU purified protein derivative (PPD) as opposed to 2 TU PPD globally, limiting comparisons. It is important to assess latent TB infection in adolescents given that they may be a target ...