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Browsing Bergen Open Research Archive by Author "Gudlaugsson, Einar"

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Now showing items 1-14 of 14

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    • Adult pancreatic hemangioma in pregnancy – concerns and considerations of a rare case 

      Søreide, Jon Arne; Greve, Ole Jakob; Gudlaugsson, Einar (Peer reviewed; Journal article, 2015-10-30)
      Background: Pancreatic tumors in pregnancy are rare but clinically challenging. Careful diagnostic workup, including appropriate imaging examinations, should be performed to evaluate surgery indications and timing . In the ...
    • Discrimination of grade 2 and 3 cervical intraepithelial neoplasia by means of analysis of water soluble proteins recovered from cervical biopsies 

      Uleberg, Kai-Erik; Munk, Ane Cecilie; Brede, Cato; Gudlaugsson, Einar; Diermen, Bianca van; Skaland, Ivar; Malpica, Anais; Janssen, Emilius Adrianus Maria; Hjelle, Anne; Baak, Jan P. A. (Peer reviewed; Journal article, 2011-06-28)
      Background: Cervical intraepithelial neoplasia (CIN) grades 2 and 3 are usually grouped and treated in the same way as “high grade”, in spite of their different risk to cancer progression and spontaneous regression rates. ...
    • Epidemiology and classification of gastroenteropancreatic neuroendocrine neoplasms using current coding criteria 

      Sandvik, Oddvar Mathias; Søreide, Kjetil; Gudlaugsson, Einar; Kvaløy, Jan Terje; Søreide, Jon Arne (Peer reviewed; Journal article, 2016-02)
      Background: The lack of uniform criteria for coding of gastroenteropancreatic neuroendocrine neoplasia (GEP-NEN) has hampered previous epidemiological studies. The epidemiology of GEP-NEN was investigated in this study ...
    • A gene signature identifying CIN3 regression and cervical cancer survival 

      Halle, Mari Kyllesø; Munk, Ane Cecilie Dæhli; Engesæter, Birgit Øvstebø; Akbari, Saleha; Frafjord, Astri; Høivik, Erling Andre; Forsse, David Erik; Fasmer, Kristine Eldevik; Woie, Kathrine; Haldorsen, Ingfrid S.; Bertelsen, Bjørn; Janssen, Emiel; Gudlaugsson, Einar; Krakstad, Camilla; Øvestad, Irene Tveiterås (Journal article; Peer reviewed, 2021-11-16)
      The purpose of this study was to establish a gene signature that may predict CIN3 regression and that may aid in selecting patients who may safely refrain from conization. Oncomine mRNA data including 398 immune-related ...
    • Hepatoid adenocarcinoma of the stomach - Proper identification and treatment remain a challenge 

      Søreide, Jon Arne; Greve, Ole Jacob; Gudlaugsson, Einar; Størset, Svein (Peer reviewed; Journal article, 2016)
      Objective: The term hepatoid adenocarcinoma (HAC) of the stomach was introduced three decades ago with the observation of high serum α-fetoprotein (AFP) levels in some gastric adenocarcinoma patients. This very rare gastric ...
    • High-Grade Cervical Intraepithelial Neoplasia (CIN) Associates with Increased Proliferation and Attenuated Immune Signaling 

      Øvestad, Irene Tveiterås; Engesæter, Birgit Øvstebø; Halle, Mari Kyllesø; Akbari, Saleha; Bicskei, Beatrix; Lapin, Morten; Austdal, Marie; Janssen, Emiel; Krakstad, Camilla; Lillesand, Melinda; Nordhus, Marit; Munk, Ane Cecilie Dæhli; Gudlaugsson, Einar (Journal article; Peer reviewed, 2021)
      Implementation of high-risk human papilloma virus (HPV) screening and the increasing proportion of HPV vaccinated women in the screening program will reduce the percentage of HPV positive women with oncogenic potential. ...
    • Influence of pre-operative oral carbohydrate loading vs. standard fasting on tumor proliferation and clinical outcome in breast cancer patients - a randomized trial 

      Lende, Tone Hoel; Austdal, Marie; Varhaugvik, Anne Elin; Skaland, Ivar; Gudlaugsson, Einar; Kvaløy, Jan Terje; Akslen, Lars A.; Søiland, Håvard; Janssen, Emiel; Baak, Jan P.A. (Peer reviewed; Journal article, 2019-11-08)
      Background: Conflicting results have been reported on the influence of carbohydrates in breast cancer. Objective: To determine the influence of pre-operative per-oral carbohydrate load on proliferation in breast tumors. ...
    • Metabolic consequences of perioperative oral carbohydrates in breast cancer patients - an explorative study 

      Lende, Tone Hoel; Austdal, Marie; Bathen, Tone Frost; Varhaugvik, Anne Elin; Skaland, Ivar; Gudlaugsson, Einar; Egeland, Nina Gran; Lunde, Siri; Akslen, Lars A.; Jonsdottir, Kristin; Janssen, Emiel; Søiland, Håvard; Baak, Jan P.A. (Peer reviewed; Journal article, 2019-12-04)
      Background: The metabolic consequences of preoperative carbohydrate load in breast cancer patients are not known. The present explorative study investigated the systemic and tumor metabolic changes after preoperative ...
    • Olaparib monotherapy as primary treatment in unselected triple negative breast cancer 

      Eikesdal, Hans Petter; Yndestad, Synnøve; Elzawahry, Asmaa; Llop-Guevara, Alba; Gilje, Bjørnar; Blix, Egil Støre; Espelid, Helge; Lundgren, Steinar; Geisler, Jürgen; Vagstad, Geirfinn; Venizelos, Andreas; Minsaas, Laura; Leirvaag, Beryl; Gudlaugsson, Einar; Vintermyr, Olav Karsten; Aase, Hildegunn Siv; Aas, Turid; Balmaña, Judith; Serra, Violeta; Janssen, Emiel; Knappskog, Stian; Lønning, Per Eystein (Journal article; Peer reviewed, 2020)
      Background The antitumor efficacy of PARP inhibitors (PARPi) for breast cancer patients harboring germline BRCA1/2 (gBRCA1/2) mutations is well established. While PARPi monotherapy was ineffective in patients with metastatic ...
    • The overriding role of surgery and tumor grade for long-term survival in patients with gastroenteropancreatic neuroendocrine neoplasms: A population-based cohort study 

      Søreide, Jon Arne; Kvaløy, Jan Terje; Lea, Dordi; Sandvik, Oddvar M.; Al-Saiddi, Mohammed; Haslerud, Torjan M.; Garresori, Herish; Karlsen, Lars Normann; Gudlaugsson, Einar; Søreide, Kjetil (Journal article; Peer reviewed, 2021)
      Background Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) comprise a heterogeneous disease group. Factors that affect long-term survival remain uncertain. Complete population-representative cohorts with long-term ...
    • Prevalence of PD‑L1 expression is associated with EMAST, density of peritumoral T‑cells and recurrence‑free survival in operable non‑metastatic colorectal cancer 

      Watson, Martin Matthew Christian; Lea, Dordi; Gudlaugsson, Einar; Skaland, Ivar; Hagland, Hanne Røland; Søreide, Kjetil (Journal article; Peer reviewed, 2020-04-20)
      Introduction Microsatellite instability (MSI) predict response to anti-PD1 immunotherapy in colorectal cancer (CRC). CRCs with MSI have higher infiltration of immune cells related to a better survival. Elevated Microsatellite ...
    • Proliferation, lymph vessel invasion and histologic type as prognostic factors in lymph node negative breast cancer 

      Gudlaugsson, Einar (Doctoral thesis, 2011-12-14)
      Breast cancer is a leading cause of cancer mortality among women in the western world, second only to lung cancer. Since the mammography screening program in Norway started in 1995, 70% and more of all new breast cancers ...
    • Reproducibility and prognostic value of WHO1973 and WHO2004 grading systems in TaT1 urothelial carcinoma of the urinary bladder 

      Mangrud, Målfrid Ok; Waalen, Rune; Gudlaugsson, Einar; Dalen, Ingvild; Tasdemir, Ilker; Janssen, Emilius Adrianus Maria; Baak, Jan P.A. (Peer reviewed; Journal article, 2014-01-07)
      Background: European treatment guidelines of TaT1 urinary bladder urothelial carcinomas depend highly on stage and WHO1973-grade but grading reproducibility is wanting. The newer WHO2004 grading system is still debated and ...
    • A template to quantify the location and density of CD3 + and CD8 + tumor-infiltrating lymphocytes in colon cancer by digital pathology on whole slides for an objective, standardized immune score assessment 

      Lea, Dordi; Watson, Martin Matthew Christian; Skaland, Ivar; Hagland, Hanne Røland; Lillesand, Melinda; Gudlaugsson, Einar; Søreide, Kjetil (Journal article; Peer reviewed, 2021)
      Background: In colon cancer, the location and density of tumor-infiltrating lymphocytes (TILs) can classify patients into low and high-risk groups for prognostication. While a commercially available ‘Immunoscore®’ exists, ...

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