Browsing Bergen Open Research Archive by Author "Gullberg, Elon Donald"

Now showing items 1-4 of 4

    • Collagen Assembly at the Cell Surface: Dogmas Revisited 

      Musiime, Moses; Chang, Joan; Hansen, Uwe; Kadler, Karl E.; Zeltz, Cedric; Gullberg, Elon Donald (Journal article; Peer reviewed, 2021)
      With the increased awareness about the importance of the composition, organization, and stiffness of the extracellular matrix (ECM) for tissue homeostasis, there is a renewed need to understand the details of how cells ...

    • Integrin α11β1 in tumor fibrosis: more than just another cancer-associated fibroblast biomarker? 

      Zeltz, Cedric; Navab, Roya; Heljasvaara, Ritva Leena; Gullberg, Marion Kusche; Lu, Ning; Tsao, Ming-Sound; Gullberg, Elon Donald (Journal article; Peer reviewed, 2022)
      There is currently an increased interest in understanding the role of the tumor microenvironment (TME) in tumor growth and progression. In this context the role of integrins in cancer-associated fibroblasts (CAFs) will ...

    • Selectivity of the collagen-binding integrin inhibitors, TC-I-15 and obtustatin 

      Hunter, Emma J; Hamaia, Samir W.; Gullberg, Elon Donald; Malcor, Jean-Daniel; Farndale, Richard W. (Journal article; Peer reviewed, 2021)
      Integrins are a family of 24 adhesion receptors which are both widely-expressed and important in many pathophysiological cellular processes, from embryonic development to cancer metastasis. Hence, integrin inhibitors are ...

    • Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis 

      Martínez-Nieto, Guillermo A.; Teppo, Hanna-Riikka; Petrelius, Noora; Izzi, Valerio; Devarajan, Raman; Petäistö, Tiina; Liu, Hengshuo; Kim, Kris S.; Karppinen, Sanna-Maria; Ruotsalainen, Heli; Koivunen, Jarkko; Mäki, Joni M.; Walker, Gilbert C.; Pihlajaniemi, Taina; Gullberg, Elon Donald; Heljasvaara, Ritva Leena (Journal article; Peer reviewed, 2022)
      Integrin α11β1 is a collagen-binding integrin that is needed to induce and maintain the myofibroblast phenotype in fibrotic tissues and during wound healing. The expression of the α11 is upregulated in cancer-associated ...