Browsing Bergen Open Research Archive by Author "Gullestad, Lars"
Now showing items 1-7 of 7
-
The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection
Trøseid, Marius; Mayerhofer, Christiane Caroline; Broch, Kaspar; Arora, Satish; Svardal, Asbjørn M.; Hov, Johannes Espolin Roksund; Andreassen, Arne K.; Gude, Einar; Karason, Kristjan; Dellgren, Gøran; Berge, Rolf Kristian; Gullestad, Lars; Aukrust, Pål; Ueland, Thor (Peer reviewed; Journal article, 2019)BACKGROUND: Alterations in the partly microbiota-dependent carnitine–γ-butyrobetaine (γBB)–trimethylamine N-oxide (TMAO) pathway have been linked to the progression of heart failure and atherosclerotic disease. We evaluated ... -
Krill oil attenuates left ventricular dilatation after myocardial infarction in rats
Fosshaug, Linn Elisabeth; Berge, Rolf Kristian; Beitnes, Jan Otto; Berge, Kjetil; Vik, Hogne; Aukrust, Pål; Gullestad, Lars; Vinge, Leif Erik; Øie, Erik (Peer reviewed; Journal article, 2011-12-29)Background: In the western world, heart failure (HF) is one of the most important causes of cardiovascular mortality. Supplement with n-3 polyunsaturated fatty acids (PUFA) has been shown to improve cardiac function in HF ... -
Long-Term Outcomes of Invasive vs Conservative Strategies for Older Patients With Non–ST-Segment Elevation Acute Coronary Syndromes
Berg, Erlend; Tegn, Nicolai Kloumann; Abdelnoor, Michael; Ryalen, Pål Christie; Røysland, Kjetil; Aaberge, Lars; Eek, Christian; Øie, Erik Harald; Juliebø, Vibeke; Gjertsen, Erik; Ranhoff, Anette Hylen; Gullestad, Lars; Nordstrand, Njord; Bendz, Bjørn (Journal article; Peer reviewed, 2023)Background Non–ST-segment elevation acute coronary syndrome (NSTE-ACS) is a frequent cause of hospital admission in older people, but clinical trials targeting this population are scarce. Objectives The After Eighty ... -
Low fibre intake is associated with gut microbiota alterations in chronic heart failure
Mayerhofer, Cristiane C.K.; Kummen, Martin; Holm, Kristian; Broch, Kaspar; Awoyemi, Ayodeji Olawale; Vestad, Beate; Larsen, Christopher Storm; Seljeflot, Ingebjørg; Ueland, Thor; Bohov, Pavol; Berge, Rolf Kristian; Svardal, Asbjørn M.; Gullestad, Lars; Yndestad, Arne; Aukrust, Pål; Hov, Johannes Espolin Roksund; Trøseid, Marius (Journal article; Peer reviewed, 2020)Aims Recent reports have suggested that patients with heart failure (HF) have an altered gut microbiota composition; however, associations with diet remain largely uninvestigated. We aimed to explore differences in the ... -
The predictive value of depression in the years after heart transplantation for mortality during long-term follow-up
Bürker, Britta Susanne; Gullestad, Lars; Gude, Einar; Havik, Odd E.; Relbo, Anne; Grov, Ingelin; Andreassen, Arne K.; Fiane, Arnt E; Haraldsen, Ira Hebold; Dew, Mary Amanda; Andersson, Stein; Malt, Ulrik Fredrik (Journal article; Peer reviewed, 2019)Objective Current understanding of the prognostic impact of depression on mortality after heart transplantation (HTx) is limited. We examined whether depression after HTx is a predictor of mortality during extended ... -
Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial
Awoyemi, Ayodeji Olawale; Mayerhofer, Cristiane; Felix, Alex S.; Hov, Johannes Espolin Roksund; Moscavitch, Samuel D.; Lappegård, Knut Tore; Hovland, Anders; Halvorsen, Sigrun; Halvorsen, Bente; Gregersen, Ida; Svardal, Asbjørn M.; Berge, Rolf Kristian; Hansen, Simen Hyll; Götz, Alexandra; Holm, Kristian; Aukrust, Pål; Åkra, Sissel; Seljeflot, Ingebjørg; Solheim, Svein; Lorenzo, Andrea; Gullestad, Lars; Trøseid, Marius; Broch, Kaspar (Journal article; Peer reviewed, 2021)Background The gut microbiota represents a potential treatment target in heart failure (HF) through microbial metabolites such as trimethylamine N-oxide (TMAO) and systemic inflammation. Treatment with the probiotic yeast ... -
Rosuvastatin alters the genetic composition of the human gut microbiome
Kummen, Martin; Solberg, Ole Geir; Larsen, Christopher Storm; Holm, Kristian; Ragnarsson, Asgrimur; Trøseid, Marius; Vestad, Beate; Skårdal, Rita; Yndestad, Arne; Ueland, Thor; Svardal, Asbjørn M.; Berge, Rolf Kristian; Seljeflot, Ingebjørg; Gullestad, Lars; Karlsen, Tom Hemming; Aaberge, Lars; Aukrust, Pål; Hov, Johannes Espolin Roksund (Journal article; Peer reviewed, 2020)The gut microbiome contributes to the variation of blood lipid levels, and secondary bile acids are associated with the effect of statins. Yet, our knowledge of how statins, one of our most common drug groups, affect the ...