Browsing Bergen Open Research Archive by Author "Gundersen, Doris Irene"
Now showing items 1-10 of 10
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Amelioration of Severe TNBS Induced Colitis by Novel AP-1 and NF-κB Inhibitors in Rats
El-Salhy, Magdy; Umezawa, Kazuo; Gilja, Odd Helge; Hatlebakk, Jan G; Gundersen, Doris Irene; Hausken, Trygve (Peer reviewed; Journal article, 2014-01-30)AP-1 and NF-κB inhibitors, namely, DTCM-G and DHMEQ, were investigated in male Wistar rats with severe colitis, induced by TNBS. The animals were randomized into 3 groups. The control group received 0.5 mL of 0.5% of the ... -
Diet in irritable bowel syndrome
El-Salhy, Magdy; Gundersen, Doris Irene (Peer reviewed; Journal article, 2015-04-14)Irritable bowel syndrome (IBS) is a common chronic gastrointestinal disorder that is characterized by intermittent abdominal pain/discomfort, altered bowel habits and abdominal bloating/distension. This review aimed at ... -
Dietary guidance normalizes large intestinal endocrine cell densities in patients with irritable bowel syndrome
Mazzawi, Tarek; Hausken, Trygve; Gundersen, Doris Irene; El-Salhy, Magdy (Peer reviewed; Journal article, 2015-11-25)Background/Objectives: To determine the large intestinal endocrine cell types affected following dietary guidance in patients with irritable bowel syndrome (IBS). Subjects/Methods: The study included 13 IBS patients and ... -
Duodenal Chromogranin A Cell Density as a Biomarker for the Diagnosis of Irritable Bowel Syndrome
El-Salhy, Magdy; Gilja, Odd Helge; Gundersen, Doris Irene; Hatlebakk, Jan G; Hausken, Trygve (Peer reviewed; Journal article, 2014-06-16)Background and Aim. Chromogranin A (CgA) is a common marker for endocrine cells. The density of duodenal CgA cells is reduced in patients with irritable bowel syndrome (IBS). Methods. The present study was undertaken to ... -
Effects of dietary guidance on the symptoms, quality of life and habitual dietary intake of patients with irritable bowel syndrome
Mazzawi, Tarek; Hausken, Trygve; Gundersen, Doris Irene; El-Salhy, Magdy (Peer reviewed; Journal article, 2013-09)Diet is important in triggering the symptoms of irritable bowel syndrome (IBS). This study investigated the impact of dietary guidance on the symptoms, quality of life and habitual diet of patients with IBS. Forty‑six ... -
Endocrine cells in the ileum of patients with irritable bowel syndrome
El-Salhy, Magdy; Gilja, Odd Helge; Gundersen, Doris Irene; Hatlebakk, Jan G; Hausken, Trygve (Peer reviewed; Journal article, 2014-03-07)AIM: To study the ileal endocrine cell types in irritable bowel syndrome (IBS) patients. METHODS: Ninety-eight patients with IBS (77 females and 21 males; mean age 35 years, range 18-66 years) were included, of which 35 ... -
Endocrine cells in the oxyntic mucosa of the stomach in patients with irritable bowel syndrome
El-Salhy, Magdy; Gilja, Odd Helge; Gundersen, Doris Irene; Hausken, Trygve (Peer reviewed; Journal article, 2014-05)AIM: To study the different endocrine cell types in the oxyntic mucosa of patients with irritable bowel syndrome (IBS). METHODS: Seventy-six patients with IBS were included in the study (62 females and 14 males; mean age ... -
Increased chromogranin A cell density in the large intestine of patients with irritable bowel syndrome after receiving dietary guidance
Mazzawi, Tarek; Gundersen, Doris Irene; Hausken, Trygve; El-Salhy, Magdy (Peer reviewed; Journal article, 2015)The large intestine contains five types of endocrine cells that regulate its functions by sensing its luminal contents and releasing specific hormones. Chromogranin A (CgA) is a common marker for the gastrointestinal ... -
Interaction between ingested nutrients and gut endocrine cells in patients with irritable bowel syndrome (Review)
El-Salhy, Magdy; Gilja, Odd Helge; Gundersen, Doris Irene; Hatlebakk, Jan G; Hausken, Trygve (Peer reviewed; Journal article, 2014-08)Several endocrine cell abnormalities have been reported in different segments of the gastrointestinal tract of patients with irritable bowel syndrome (IBS). These cells have specialized microvilli that project into the ... -
Is irritable bowel syndrome an organic disorder?
El-Salhy, Magdy; Gundersen, Doris Irene; Gilja, Odd Helge; Hatlebakk, Jan G; Hausken, Trygve (Peer reviewed; Journal article, 2014-01-14)Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that is generally considered to be functional because there appears to be no associated anatomical defect. Stress and psychological factors are thought ...