Browsing Bergen Open Research Archive by Author "Guren, Marianne"
Now showing items 1-8 of 8
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Accurate population-based model for individual prediction of colon cancer recurrence
Österman, Erik; Ekström, Joakim; Sjöblom, Tobias; Kørner, Hartwig; Myklebust, Tor Åge; Guren, Marianne; Glimelius, Bengt (Journal article; Peer reviewed, 2021)Background Prediction models are useful tools in the clinical management of colon cancer patients, particularly when estimating the recurrence rate and, thus, the need for adjuvant treatment. However, the most used models ... -
Characteristics and fate of patients with rectal cancer not entering a curative-intent treatment pathway: A complete nationwide registry cohort of 3,304 patients
Kørner, Hartwig; Guren, Marianne; Larsen, Inger Kristin; Haugen, Dagny Renata Faksvåg; Søreide, Kjetil; Kørner, Leif Roland; Søreide, Jon Arne (Journal article; Peer reviewed, 2022)Background: Treatment options for advanced and metastatic rectal cancer have increased during the past decades. However, a considerable proportion of the patients are not eligible for curative treatment, and data on this ... -
Complete response of metastatic microsatellite-stable BRAF V600E colorectal cancer to first-line oxaliplatin-based chemotherapy and immune checkpoint blockade
Ree, Anne Hansen; Høye, Eirik; Esbensen, Qin Ying; Røberg Beitnes, Ann-Christin; Negård, Anne; Bernklev, Linn; Tetlie, Linn Kruse; Fretland, Åsmund Avdem; Hamre, Hanne Mari; Kersten, Christian; Hofsli, Eva; Guren, Marianne; Sorbye, Halfdan; Nilsen, Hilde; Flatmark, Kjersti; Meltzer, Sebastian (Journal article; Peer reviewed, 2024)The randomized METIMMOX trial (NCT03388190) examined if patients with previously untreated, unresectable abdominal metastases from microsatellite-stable (MSS) colorectal cancer (CRC) might benefit from potentially immunogenic, ... -
Distinctions Between Self-Report and Performance-Based Measures of Physical Function in Older Patients Prior to Chemotherapy
Torstveit, Ann Helen; Løyland, Borghild; Grov, Ellen Karine; Guren, Marianne; Paul, Steven M.; Ritchie, Christine; Vistad, Ingvild; Miaskowski, Christine; Utne, Inger (Journal article; Peer reviewed, 2021)Background: The maintenance of physical function (PF) is an extremely important outcome for older adults. Objective: The aims of this study were to, identify differences in subjective and objective measures of PF between ... -
Early radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer
Meltzer, Sebastian; Negård, Anne; Bakke, Kine Mari; Hamre, Hanne Mari; Kersten, Christian; Hofsli, Eva; Guren, Marianne; Sorbye, Halfdan; Flatmark, Kjersti; Ree, Anne Hansen (Journal article; Peer reviewed, 2022)Background: Immune checkpoint blockade (ICB) results in radiologic tumour response dynamics that differ from chemotherapy efficacy measures and require an early signal of clinical utility. Methods: Previously untreated, ... -
First-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer—the randomised METIMMOX trial
Ree, Anne Hansen; Saltyte Benth, Jurate; Hamre, Hanne Mari; Kersten, Christian; Hofsli, Eva; Guren, Marianne; Sorbye, Halfdan; Johansen, Christin; Negård, Anne; Bjørnetrø, Tonje; Nilsen, Hilde; Berg, Jens Petter; Flatmark, Kjersti; Meltzer, Sebastian (Journal article; Peer reviewed, 2024)Background: We evaluated first-line treatment of metastatic microsatellite-stable colorectal cancer with short-course oxaliplatin-based chemotherapy alternating with immune checkpoint blockade. Methods: Patients were ... -
One-year excess mortality and treatment in surgically treated patients with colorectal cancer: A EURECCA European comparison
Bahadoer, Renu R.; Bastiaannet, Esther; Claassen, Yvette H.M.; van der Mark, Marianne; van Eycken, Elizabeth; Verbeeck, Julie; Guren, Marianne; Kørner, Hartwig; Martling, Anna; Johansson, Robert; van de Velde, Cornelis J.H.; Dekker, Jan Willem T. (Journal article; Peer reviewed, 2021)Background Mortality in the first postoperative year represents an accurate reflection of the perioperative risk after colorectal cancer surgery. This research compares one-year mortality after surgery divided into three ... -
The survival gap between young and older patients after surgical resection for colorectal cancer remains largely based on early mortality: A EURECCA comparison of four European countries.
Bahadoer, Renu R.; Bastiaannet, Esther; Peeters, Koen C.M.J.; van Eycken, Elizabeth; Verbeeck, Julie; Guren, Marianne; Kørner, Hartwig; Martling, Anna; Johansson, Robert; van de Velde, Cornelis J.H.; Dekker, Jan Willem T. (Journal article; Peer reviewed, 2022)Background: A decade ago, it was demonstrated that the difference in survival between older patients and younger patients with colorectal cancer (CRC) was mainly due to mortality in the first postoperative year. Over the ...