Browsing Bergen Open Research Archive by Author "Haaverstad, Rune"
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Baseline frailty status and outcomes important for shared decision‑making in older adults receiving transcatheter aortic valve implantation, a prospective observational study
Skaar, Elisabeth; Øksnes, Anja; Eide, Leslie SP; Norekvål, Tone Merete; Ranhoff, Anette Hylen; Nordrehaug, Jan Erik; Forman, Daniel Edward; Schoennberger, Andreas W.; Hufthammer, Karl Ove; Kuiper, Karel Kier-Jan; Bleie, Øyvind; Packer, Erik; Langørgen, Jørund; Haaverstad, Rune; Schaufel, Margrethe Aase (Journal article; Peer reviewed, 2021)Aims The objective of this study was to examine baseline frailty status (including cognitive deficits) and important clinical outcomes, to inform shared decision-making in older adults receiving transcatheter aortic valve ... -
Carvedilol-enriched cold oxygenated blood cardioplegia improves left ventricular diastolic function after weaning from cardiopulmonary bypass
Dahle, Geir Olav; Salminen, Pirjo-Riitta; Moen, Christian Arvei; Eliassen, Finn; Nygreen, Else Loholdt; Kytö, Ville; Saukko, Pekka; Haaverstad, Rune; Matre, Knut; Grong, Ketil (Peer reviewed; Journal article, 2016-08)Objectives: To investigate whether adding carvedilol, a nonselective β- and selective α1-receptor blocking agent with antioxidant properties, to oxygenated blood cardioplegia improves myocardial function after weaning from ... -
Clinical Efficacy of Combined Surgical Patient Safety System and the World Health Organization’s Checklists in Surgery. A Nonrandomized Clinical Trial
Storesund, Anette; Haugen, Arvid Steinar; Flaatten, Hans; Nortvedt, Monica W.; Eide, Geir Egil; Boermeester, Marja A.; Sevdalis, Nick; Tveiten, Øystein; Mahesparan, Ruby; Hjallen, Bjørg Merete; Fevang, Jonas Meling; Størksen, Catrine Hjelle; Thornhill, Heidi Frances; Sjøen, Gunnar Helge; Kolseth, Solveig Moss; Haaverstad, Rune; Sandli, Oda Kristine; Søfteland, Eirik (Peer reviewed; Journal article, 2020)Importance: Checklists have been shown to improve patient outcomes in surgery. The intraoperatively used World Health Organization surgical safety checklist (WHO SSC) is now mandatory in many countries. The only evidenced ... -
Comorbidities, injury severity and complications predict mortality in thoracic trauma
Fokkema, Anne T.; Johannesdottir, Bergros Kristin; Wendt, Klaus; Haaverstad, Rune; Reininga, Inge H. F.; Geisner, Thomas (Journal article; Peer reviewed, 2022)Purpose Thoracic trauma accounts for 25–50% of posttraumatic mortality. Data on epidemiology of thoracic trauma in Scandinavia and risk factors for mortality are scarce. This study aims to provide an overview of epidemiology, ... -
Comparison of frequency, risk factors, and time course of postoperative delirium in octogenarians after transcatheter aortic valve implantation versus surgical aortic valve replacement
Eide, Leslie Sofia Pareja; Ranhoff, Anette Hylen; Fridlund, Bengt Gotthard Anton; Haaverstad, Rune; Hufthammer, Karl Ove; Kuiper, Karel Kier-Jan; Nordrehaug, Jan Erik; Norekvål, Tone M. (Peer reviewed; Journal article, 2015-03-15)Postoperative delirium (PD) after transcatheter aortic valve implantation (TAVI) remains to be explored. We sought to (1) determine the incidence of PD in octogenarians who underwent TAVI or surgical aortic valve replacement ... -
Delirium as a Predictor of Physical and Cognitive Function in Individuals Aged 80 and Older After Transcatheter Aortic Valve Implantation or Surgical Aortic Valve Replacement
Eide, Leslie Sofia Pareja; Ranhoff, Anette Hylen; Fridlund, Bengt Gotthard Anton; Haaverstad, Rune; Hufthammer, Karl Ove; Kuiper, Karel Kier-Jan; Nordrehaug, Jan Erik; Norekvål, Tone M. (Peer reviewed; Journal article, 2016-06)Objectives: To determine how development of delirium after surgical aortic valve replacement (SAVR) or transcatheter aortic valve implantation (TAVI) could predict activity of daily living (ADL) and instrumental ADLs (IADL) ... -
Development and validation of patients' surgical safety checklist
Harris, Kristin; Søfteland, Eirik; Moi, Asgjerd Litleré; Harthug, Stig; Ravnøy, Mette; Storesund, Anette; Jurmy, Elaheh; Thakkar, Bhaumik; Haaverstad, Rune; Skeie, Eli; Valen, Hilde Wæhle; Sevdalis, Nick; Haugen, Arvid Steinar (Journal article; Peer reviewed, 2022)Background: Poor uptake and understanding of critical perioperative information represent a major safety risk for surgical patients. Implementing a patient-driven surgical safety checklist might enhance the way critical ... -
Esmolol added in repeated, cold, oxygenated blood cardioplegia improves myocardial function after cardiopulmonary bypass
Dahle, Geir Olav; Salminen, Pirjo-Riitta; Moen, Christian Arvei; Eliassen, Finn; Jonassen, Anne K.; Haaverstad, Rune; Matre, Knut; Grong, Ketil (Peer reviewed; Journal article, 2015-06)Objective: This study investigated if the β-receptor blocking agent esmolol, added to standard oxygenated blood cardioplegia, improved myocardial function after weaning from bypass. Design: A block-randomized, blinded ... -
Finite element analysis of mitral valve annuloplasty in Barlow's disease
Aguilera, Hans Martin; Urheim, Stig; Persson, Robert; Haaverstad, Rune; Skallerud, Bjørn Helge; Prot, Victorien Emile (Journal article; Peer reviewed, 2022)Barlow’s Disease affects the entire mitral valve apparatus causing mitral regurgitation. Standard annuloplasty procedures lead to an average of 55% annular area reduction of the end diastolic pre-operative annular area in ... -
In silico analysis provides insights for patient-specific annuloplasty in Barlow’s disease
Aguilera, Hans Martin Dahl; Persson, Robert; Haaverstad, Rune; Skallerud, Bjørn Helge; Prot, Victorien Emile; Urheim, Stig (Journal article; Peer reviewed, 2023)Objective To predict the required mitral annular area reduction in patients with Barlow's disease to obtain a predefined leaflet area index by a novel in silico modeling method. Methods Three-dimensional echocardiography ... -
Indwelling urinary catheters, aortic valve treatment and delirium: a prospective cohort study
Eide, Leslie Sofia Pareja; Ranhoff, Anette Hylen; Lauck, Sandra; Fridlund, Bengt; Haaverstad, Rune; Hufthammer, Karl Ove; Kuiper, Karel Kier-Jan; Nordrehaug, Jan E; Norekvål, Tone M. (Peer reviewed; Journal article, 2018-11-01)Objectives To determine whether an association exists between delirium and length of time indwelling urine catheters (IUC) are used in octogenarian patients treated with surgical aortic valve treatment (SAVR) or transcatheter ... -
Left ventricular dysfunction after two hours of polarizing or depolarizing cardioplegic arrest in a porcine model
Aass, Terje; Stangeland, Lodve; Moen, Christian Arvei; Solholm, Atle; Dahle, Geir Olav; Chambers, David J.; Urban, Malte; Nesheim, Knut; Haaverstad, Rune; Matre, Knut; Grong, Ketil (Peer reviewed; Journal article, 2019)Introduction: This experimental study compares myocardial function after prolonged arrest by St. Thomas’ Hospital polarizing cardioplegic solution (esmolol, adenosine, Mg2+) with depolarizing (hyperkalaemic) St. Thomas’ ... -
Left ventricular venting during extracorporeal membrane oxygenation; the effects on cardiac performance in a porcine model of critical post-cardiotomy failure
Solholm, Atle; Salminen, Pirjo-Riitta; Stangeland, Lodve; Dahle, Geir Olav; Mongstad, Arve; Svenheim, Bård; Zhang, Liqun; Haaverstad, Rune; Grong, Ketil (Journal article; Peer reviewed, 2022)Introduction Left ventricular distension is a major concern with postcardiotomy veno-arterial extracorporeal membrane oxygenation (VA-ECMO) supporting a critical heart failure after cardiac surgery. This porcine study ... -
Mechanical behavior and collagen structure of degenerative mitral valve leaflets and a finite element model of primary mitral regurgitation
Sadeghinia, Mohammadjavad; Aguilera, Hans Martin Dahl; Urheim, Stig; Persson, Robert; Ellensen, Vegard Skalstad; Haaverstad, Rune; Holzapfel, Gerhard; Skallerud, Bjørn Helge; Prot, Victorien Emile (Journal article; Peer reviewed, 2023)Degenerative mitral valve disease is the main cause of primary mitral regurgitation with two phenotypes: fibroelastic deficiency (FED) often with localized myxomatous degeneration and diffuse myxomatous degeneration or ... -
Mitral annular dynamics are influenced by left ventricular load and contractility in an acute animal model
Persson, Robert Matongo; Aguilera, Hans Martin Dahl; Kvitting, Jon Peder Escobar; Grong, Ketil; Prot, Victorien Emile; Salminen, Pirjo-Riitta; Svenheim, Bård; Leiknes, Anita; Stangeland, Lodve; Haaverstad, Rune; Urheim, Stig (Journal article; Peer reviewed, 2023)The purpose of this study was to investigate the effects of loading conditions and left ventricular (LV) contractility on mitral annular dynamics. In 10 anesthetized pigs, eight piezoelectric transducers were implanted ... -
Myocardial energy metabolism and ultrastructure with polarizing and depolarizing cardioplegia in a porcine model
Aass, Terje; Stangeland, Lodve; Chambers, David J.; Hallstrõm, Seth; Rossmann, Christine; Podesser, Bruno K.; Urban, Malte; Nesheim, Knut; Haaverstad, Rune; Matre, Knut; Grong, Ketil (Peer reviewed; Journal article, 2017-03-02)OBJECTIVES: This study investigated whether the novel St. Thomas’ Hospital polarizing cardioplegic solution (STH-POL) with esmolol/adenosine/magnesium offers improved myocardial protection by reducing demands for high-energy ... -
Myocardial function after polarizing versus depolarizing cardiac arrest with blood cardioplegia in a porcine model of cardiopulmonary bypass
Aass, Terje; Stangeland, Lodve; Moen, Christian Arvei; Salminen, Pirjo-Riitta; Dahle, Geir Olav; Chambers, David J.; Markou, Thomais; Eliassen, Finn; Urban, Malte; Haaverstad, Rune; Matre, Knut; Grong, Ketil (Peer reviewed; Journal article, 2016)OBJECTIVES Potassium-based depolarizing St Thomas' Hospital cardioplegic solution No 2 administered as intermittent, oxygenated blood is considered as a gold standard for myocardial protection during cardiac surgery. ... -
A novel case of impaired C-reactive protein response following open-heart surgery: A case report and review of the literature
Vinnes, Erik Wilhelm; Lillemoen, Paul Kjetil Soldal; Persson, Robert; Meyer, Klaus; Haaverstad, Rune; Monsen, Anne-Lise Bjørke (Journal article; Peer reviewed, 2021)Background C-reactive protein (CRP) is expected to increase in response to a range of inflammatory stimuli such as infections or extensive tissue trauma. Case report We present a novel case of severely impaired CRP ... -
A novel Geriatric Assessment frailty score predicts two-year mortality after Transcatheter Aortic Valve implantation
Skaar, Elisabeth; Eide, Leslie Sofia Pareja; Norekvål, Tone M.; Ranhoff, Anette Hylen; Nordrehaug, Jan Erik; Forman, Daniel E.; Schönenberger, Anders; Hufthammer, Karl Ove; Kuiper, Karel Kier-Jan; Bleie, Øyvind; Haaverstad, Rune; Schaufel, Margrethe Aase; Packer, Erik Jerome Stene; Langørgen, Jørund (Peer reviewed; Journal article, 2018-10-31)Aims Established surgical scores have limitations in delineating risk among candidates for transcatheter aortic valve implantation (TAVI). Assessment of frailty might help to estimate the mortality risk and identify patients ... -
Octogenarian patients’ sleep and delirium experiences in hospital and four years after aortic valve replacement: a qualitative interview study
Amofah, Hege Andersen; Broström, Anders; Instenes, Irene; Fridlund, Bengt; Haaverstad, Rune; Kuiper, Karel Kier-Jan; Ranhoff, Anette Hylen; Norekvål, Tone Merete (Journal article; Peer reviewed, 2021)Objectives Sleep disturbances and delirium are frequently observed complications after surgical aortic valve replacement (SAVR) and transcutaneous aortic valve implantation (TAVI), especially in octogenarian patients. ...