• The 14-3-3 proteins in regulation of cellular metabolism 

      Kleppe, Rune; Martinez, Aurora; Døskeland, Stein Ove; Haavik, Jan (Peer reviewed; Journal article, 2011-09)
      Thirty years ago, it was discovered that 14-3-3 proteins could activate enzymes involved in amino acid metabolism. In the following decades, 14-3-3s have been shown to be involved in many different signaling pathways that ...
    • 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans 

      Sønderby, Ida Elken; van der Meer, Dennis; Moreau, Clara; Kaufmann, Tobias; Walters, G. Bragi; Ellegaard, Maria; Abdellaoui, Abdel; Ames, David; Amunts, Katrin; Andersson, Micael; Armstrong, Nicola J.; Bernard, Manon; Blackburn, Nicholas B.; Blangero, John; Boomsma, Dorret I.; Brodaty, Henry; Brouwer, Rachel M.; Bülow, Robin; Bøen, Rune; Cahn, Wiepke; Calhoun, Vince D.; Caspers, Svenja; Ching, Christopher R. K.; Cichon, Sven; Ciufolini, Simone; Crespo-Facorro, Benedicto; Curran, Joanne E.; Dale, Anders M.; Dalvie, Shareefa; Dazzan, Paola; de Geus, Eco J. C.; Zubicaray, Greig I. de; Zwarte, Sonja M. C. de; Desrivieres, Sylvane; Doherty, Joanne L.; Donohoe, Gary; Draganski, Bogdan; Ehrlich, Stefan; Eising, Else; Espeseth, Thomas; Fejgin, Kim; Fisher, Simon E.; Fladby, Tormod; Frei, Oleksandr; Frouin, Vincent; Fukunaga, Masaki; Gareau, Thomas; Ge, Tian; Glahn, David C.; Grabe, Hans J.; Groenewold, Nynke A.; Gustafsson, Omar; Haavik, Jan; Haberg, Asta Kristine; Hall, Jeremy; Hashimoto, Ryota; Hehir-Kwa, Jayne Y.; Hibar, Derrek P.; Hillegers, Manon H. J.; Hoffmann, Per; Holleran, Laurena; Holmes, Avram J.; Johansson, Stefan; Jönsson, Erik Gunnar; Hellard, Stephanie Francoise Claire Le; Lundervold, Arvid; Lundervold, Astri J.; Moberget, Torgeir; Nordvik, Jan Egil; Sando, Sigrid Botne; Steen, Vidar Martin; Tamnes, Christian Krog; Agartz, Ingrid; Djurovic, Srdjan; Westlye, Lars Tjelta; Andreassen, Ole; Homuth, Georg; Hottenga, Jouke-Jan; Hulshoff Pol, Hilleke E.; Ikeda, Masashi; Jahanshad, Neda; Jockwitz, Christiane; Jørgensen, Niklas R.; Kikuchi, Masataka; Knowles, Emma E. M.; Kumar, Kuldeep; Leu, Costin; Linden, David E. J.; Liu, Jingyu; Maillard, Anne M.; Martin, Nicholas G.; Martin-Brevet, Sandra; Mather, Karen A.; Mathias, Samuel R.; McMahon, Katie L.; McRae, Allan F.; Medland, Sarah E.; Meyer-Lindenberg, Andreas; Modenato, Claudia; Monereo Sánchez, Jennifer; Morris, Derek W.; Mühleisen, Thomas W.; Murray, Robin M.; Nielsen, Jacob; Nyberg, Lars; Olde Loohuis, Loes M.; Ophoff, Roel A.; Owen, Michael J.; Paus, Tomas; Pausova, Zdenka; Peralta, Juan M.; Pike, G. Bruce; Prieto, Carlos; Quinlan, Erin B.; Reinbold, Céline S.; Reis Marques, Tiago; Rucker, James J. H.; Sachdev, Perminder S.; Schofield, Peter R.; Schork, Andrew J.; Schumann, Gunter; Shin, Jean; Shumskaya, Elena; Silva, Ana I.; Sisodiya, Sanjay M.; Stein, Dan J.; Strike, Lachlan T.; Suzuki, Ikuo K.; Teumer, Alexander; Thalamuthu, Anbupalam; Tordesillas-Gutiérrez, Diana; Uhlmann, Anne; Ulfarsson, Magnus O.; van ‘t Ent, Dennis; van den Bree, Marianne B. M.; Vanderhaeghen, Pierre; Vassos, Evangelos; Wen, Wei; Wittfeld, Katharina; Wright, Margaret J.; Stefansson, Hreinn; Stefansson, Kari; Jacquemont, Sébastien; Thompson, Paul M. (Journal article; Peer reviewed, 2021)
      Low-frequency 1q21.1 distal deletion and duplication copy number variant (CNV) carriers are predisposed to multiple neurodevelopmental disorders, including schizophrenia, autism and intellectual disability. Human carriers ...
    • ADHD symptoms in neurometabolic diseases: Underlying mechanisms and clinical implications 

      Homaei, Selina Cannon; Barone, Helene; Kleppe, Rune; Betari, Nibal; Reif, Andreas; Haavik, Jan (Journal article; Peer reviewed, 2021)
      Neurometabolic diseases (NMDs) are typically caused by genetic abnormalities affecting enzyme functions, which in turn interfere with normal development and activity of the nervous system. Although the individual disorders ...
    • Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review 

      Instanes, Johanne Telnes; Klungsøyr, Kari; Halmøy, Anne; Fasmer, Ole Bernt; Haavik, Jan (Peer reviewed; Journal article, 2016)
      Objective: To systematically review, synthesize, and appraise available evidence, connecting adult ADHD (aADHD) with somatic disease. Method: Embase, Psychinfo, and Medline databases were searched for studies published ...
    • Adult attention deficit hyperactivity disorder is associated with asthma 

      Fasmer, Ole Bernt; Halmøy, Anne; Eagan, Tomas Mikal; Ødegaard, Ketil Joachim; Haavik, Jan (Peer reviewed; Journal article, 2011-08-07)
      Background: Attention deficit hyperactivity disorder (ADHD) is increasingly recognized as a common disorder not only in children, but also in the adult population. Similarly, asthma also has a substantial prevalence among ...
    • Adult attention deficit hyperactivity disorder is associated with migraine headaches 

      Fasmer, Ole Bernt; Halmøy, Anne; Ødegaard, Ketil Joachim; Haavik, Jan (Peer reviewed; Journal article, 2011-03-11)
      Attention deficit hyperactivity disorder (ADHD) is now recognized as a common disorder both in child and adult psychiatry. Adult patients with a diagnosis of ADHD (n = 572) and community controls (n = 675) responded to ...
    • Adults with attention deficit hyperactivity disorder report high symptom levels of troubled sleep, restless legs, and cataplexy 

      Bjorvatn, Bjørn; Brevik, Erlend Joramo; Lundervold, Astri; Halmøy, Anne; Posserud, Maj-Britt Rocio; Instanes, Johanne Telnes; Haavik, Jan (Peer reviewed; Journal article, 2017-09-20)
      Objective: To compare the occurrence of a spectrum of different self-reported sleep problems in adults with ADHD and a control group, and to study the impact of current ADHD medication use and clinical ADHD subtype. Method: ...
    • Adults with attention-deficit/hyperactivity disorder. A brain magnetic resonance spectroscopy study 

      Dramsdahl, Margaretha; Ersland, Lars; Plessen, Kerstin von; Haavik, Jan; Hugdahl, Kenneth; Specht, Karsten (Peer reviewed; Journal article, 2011-11-23)
      Background: Impaired cognitive control in individuals with attention-deficit/hyperactivity disorder (ADHD) may be related to a prefrontal cortical glutamatergic deficit. We assessed the glutamate level in the left and the ...
    • Analysis of structural brain asymmetries in attention-deficit/hyperactivity disorder in 39 datasets 

      Postema, Merel C.; Hoogman, Martine; Ambrosino, Sara; Asherson, Philip; Banaschewski, Tobias; Bandeira, Cibele E.; Baranov, Alexandr; Bau, Claiton H.D.; Baumeister, Sarah; Baur-Streubel, Ramona; Bellgrove, Mark A.; Biederman, Joseph; Bralten, Janita; Brandeis, Daniel; Brem, Silvia; Buitelaar, Jan K.; Busatto, Geraldo F.; Castellanos, Francisco X.; Cercignani, Mara; Chaim-Avancini, Tiffany M.; Chantiluke, Kaylita C.; Christakou, Anastasia; Coghill, David; Conzelmann, Annette; Cubillo, Ana; Cupertino, Renata B.; de Zeeuw, Patrick; Doyle, Alysa E.; Durston, Sarah; Earl, Eric A.; Epstein, Jeffery N.; Ethofer, Thomas; Fair, Damien A.; Fallgatter, Andreas J.; Faraone, Stephen V.; Frodl, Thomas; Gabel, Matt C.; Gogberashvili, Tinatin; Grevet, Eugenio H.; Haavik, Jan; Harrison, Neil A.; Hartman, Catharina A.; Heslenfeld, Dirk J.; Hoekstra, Pieter J.; Hohmann, Sarah; Høvik, Marie Farstad; Jernigan, Terry L.; Kardatzki, Bernd; Karkashadze, George A.; Kelly, Clare; Kohls, Gregor; Konrad, Kerstin; Kuntsi, Jonna; Lazaro, Luisa; Lera-Miguel, Sara; Lesch, Klaus-Peter; Louza, Mario R.; Lundervold, Astri J.; Malpas, Charles B.; Mattos, Paulo; McCarthy, Hazel; Namazova-Baranova, Leyla; Nicolau, Rosa; Nigg, Joel T.; Novotny, Stephanie E.; Oberwelland Weiss, Eileen; O'Gorman Tuura, Ruth L.; Oosterlaan, Jaap; Oranje, Bob; Paloyelis, Yannis; Pauli, Paul; Picon, Felipe A.; Plessen, Kerstin J.; Ramos-Quiroga, J. Antoni; Reif, Andreas; Reneman, Liesbeth; Rosa, Pedro G.P.; Rubia, Katya; Schrantee, Anouk; Schweren, Lizanne J.S.; Seitz, Jochen; Shaw, Philip; Silk, Tim J.; Skokauskas, Norbert; Soliva, Joan Carles; Stevens, Michael C.; Sudre, Gustavo; Tamm, Leanne; Tovar-Moll, Fernanda; van Erp, Theo G.M.; Vance, Alasdair; Vilarroya, Oscar; Vives-Gilabert, Yolanda; von Polier, Georg G.; Walitza, Susanne; Yoncheva, Yuliya N.; Zanetti, Marcus V; Ziegler, Georg C.; Glahn, David C.; Jahanshad, Neda; Medland, Sarah E.; Thompson, Paul M.; Fisher, Simon E.; Franke, Barbara; Francks, Clyde (Journal article; Peer reviewed, 2021)
      Objective Some studies have suggested alterations of structural brain asymmetry in attention-deficit/hyperactivity disorder (ADHD), but findings have been contradictory and based on small samples. Here, we performed the ...
    • Anterior cingulate gamma-aminobutyric acid concentrations and electroconvulsive therapy 

      Erchinger, Vera Jane; Miller, Jeremy; Jones, Thomas; Kessler, Ute; Bustillo, Juan R.; Haavik, Jan; Petrillo, Jonathan; Ziomek, Gregory; Hammar, Åsa; Ødegaard, Ketil Joachim; Calhoun, Vince D.; McClintock, Shawn M.; Ersland, Lars; Oltedal, Leif; Abbott, Christopher (Journal article; Peer reviewed, 2020-09-17)
      Objective The anticonvulsant hypothesis posits that ECT’s mechanism of action is related to enhancement of endogenous anticonvulsant brain mechanisms. Results of prior studies investigating the role of the inhibitory ...
    • Anxiety, mood, and substance use disorders in adult men and women with and without attention-deficit/hyperactivity disorder: A substantive and methodological overview 

      Hartman, Catharina A.; Larsson, Henrik; Vos, Melissa; Bellato, Alessio; Libutzki, Berit; Solberg, Berit Skretting; Chen, Qi; Du Rietz, Ebba; Mostert, Jeanette C.; Kittel-Schneider, Sarah; Cormand, Bru; Ribasés, Marta; Klungsøyr, Kari; Haavik, Jan; Dalsgaard, Søren; Cortese, Samuele; Faraone, Stephen; Reif, Andreas (Journal article; Peer reviewed, 2023)
      Knowledge on psychiatric comorbidity in adult ADHD is essential for prevention, detection, and treatment of these conditions. This review (1) focuses on large studies (n > 10,000; surveys, claims data, population registries) ...
    • Arc is a flexible modular protein capable of reversible self-oligomerization 

      Myrum, Craig; Baumann, Anne; Bustad, Helene J.; Flydal, Marte Innselset; Mariaule, Vincent; Alvira, Sara; Cuéllar, Jorge; Haavik, Jan; Soulé, Jonathan; Valpuesta, José María; Márquez, José Antonio; Martinez, Aurora; Bramham, Clive R. (Peer reviewed; Journal article, 2015)
      The immediate early gene product Arc (activity-regulated cytoskeleton-associated protein) is posited as a master regulator of long-term synaptic plasticity and memory. However, the physicochemical and structural properties ...
    • Association of sweetened carbonated beverage consumption during pregnancy and ADHD symptoms in the ofspring: a study from the Norwegian Mother, Father and Child Cohort Study (MoBa) 

      Kvalvik, Liv Grimstvedt; Klungsøyr, Kari; Igland, Jannicke; Caspersen, Ida Henriette; Brantsæter, Anne Lise; Solberg, Berit Skretting; Hartman, Catharina; Schweren, Lizanne Johanna Stephanie; Larsson, Henrik; Li, Lin; Forthun, Ingeborg; Johansson, Stefan; Vasquez, Alejandro Arias; Haavik, Jan (Journal article; Peer reviewed, 2022)
      Purpose Intrauterine exposures influence offspring health and development. Here we investigated maternal intake of sweetened carbonated beverages (SCB) during pregnancy and its association with ADHD symptoms in the ...
    • Associations between attention-deficit/hyperactivity disorder and autoimmune diseases are modified by sex: a population-based cross-sectional study 

      Hegvik, Tor-Arne; Instanes, Johanne Telnes; Haavik, Jan; Klungsøyr, Kari; Engeland, Anders (Peer reviewed; Journal article, 2018-05)
      Several studies have demonstrated associations between neuropsychiatric disorders, such as attention-deficit/hyperactivity disorder (ADHD), and the immune system, including autoimmune diseases. Since ADHD and many autoimmune ...
    • Attention Network Test in adults with ADHD - the impact of affective fluctuations 

      Lundervold, Astri Johansen; Adólfsdóttir, Steinunn; Halleland, Helene Barone; Halmøy, Anne; Plessen, Kerstin von; Haavik, Jan (Peer reviewed; Journal article, 2011-07-27)
      Background: The Attention Network Test (ANT) generates measures of different aspects of attention/executive function. In the present study we investigated whether adults with ADHD performed different from controls on ...
    • Attention-deficit hyperactivity disorder shares copy number variant risk with schizophrenia and autism spectrum disorder 

      Gudmundsson, Ólafur Ó.; Walters, Gudmundur Bragi; Ingason, Andrés; Johansson, Stefan; Zayats, Tetyana; Athanasiu, Lavinia; Sønderby, Ida Elken; Gustafsson, Omar; Nawaz, Muhammad Sulaman; Jónsson, Gudbjörn F.; Jónsson, Lina; Knappskog, Per; Ingvarsdóttir, Ester; Davidsdóttir, Katrin; Djurovic, Srdjan; Knudsen, Gun Peggy Strømstad; Askeland, Ragna Bugge; Haraldsdóttir, Gyda S.; Baldursson, Gísli; Magnússon, Páll; Sigurdsson, Engilbert; Gudbjartsson, Daníel Fannar; Stéfansson, Hreinn; Andreassen, Ole Andreas; Haavik, Jan; Reichborn-Kjennerud, Ted; Stefánsson, Kári (Peer reviewed; Journal article, 2019-10-17)
      Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable common childhood-onset neurodevelopmental disorder. Some rare copy number variations (CNVs) affect multiple neurodevelopmental disorders such as ...
    • Attention-deficit/hyperactivity disorder and smoking habits in pregnant women 

      Anderson, Anneli; Hegvik, Tor-Arne; Chen, Qi; Kvalvik, Liv Grimstvedt; Almqvist, Catarina; D'Onofrio, Brian M.; Hartman, Catharina A; Klungsøyr, Kari; Haavik, Jan; Tuvblad, Catherine; Larsson, Henrik (Journal article; Peer reviewed, 2020)
      Background Attention-deficit/hyperactivity disorder (ADHD) has been associated with an increased risk of tobacco smoking, and more difficulties with smoking cessation compared to non-ADHD individuals. Women with ADHD may ...
    • Attention-deficit/hyperactivity disorder in offspring of mothers with inflammatory and immune system diseases 

      Instanes, Johanne Telnes; Halmøy, Anne; Engeland, Anders; Haavik, Jan; Furu, Kari; Klungsøyr, Kari (Peer reviewed; Journal article, 2017-03)
      Background: Prenatal inflammatory mechanisms may play a role in the pathogenesis of psychiatric disorders and could be relevant for attention-deficit/hyperactivity disorder (ADHD). We investigated maternal chronic somatic ...
    • A candidate gene investigation of methylphenidate response in adult attention-deficit/hyperactivity disorder patients: results from a naturalistic study 

      Hegvik, Tor-Arne; Jacobsen, Kaya Kvarme; Fredriksen, Mats; Zayats, Tetyana; Haavik, Jan (Peer reviewed; Journal article, 2016-08)
      Attention-deficit/hyperactivity disorder (ADHD) is a common childhood onset neuropsychiatric disorder with a complex and heterogeneous symptomatology. Persistence of ADHD symptoms into adulthood is common. Methylphenidate ...
    • Case report: ADHD and prognosis in tyrosinemia type 1 

      Halleland, Helene; Elgen, Irene Bircow; Bliksrud, Yngve Thomas; Hansen, Eirik Vangsøy; Skavhellen, Rita Rigmor; Furevik, Magne Ivar; Haavik, Jan (Journal article; Peer reviewed, 2023-07-18)
      Neurometabolic disorders such as tyrosinemia type 1 (TYRSN1) may interfere with brain metabolism and show symptoms of attention-deficit hyperactivity disorder (ADHD) in patients treated with the enzyme inhibitor nitisinone ...