Blar i Bergen Open Research Archive på forfatter "Hagen, Espen"

Viser treff 1-5 av 5

    • Alterations in schizophrenia-associated genes can lead to increased power in delta oscillations 

      Mäki-Marttunen, Tuomo; Krull, Florian; Bettella, Francesco; Hagen, Espen; Næss, Solveig; Ness, Torbjørn V; Moberget, Torgeir; Elvsåshagen, Torbjørn; Metzner, Christoph; Devor, Anna; Edwards, Andrew G.; Fyhn, Marianne; Djurovic, Srdjan; Dale, Anders; Andreassen, Ole Andreas; Einevoll, Gaute (Peer reviewed; Journal article, 2019-02)
      Genome-wide association studies have implicated many ion channels in schizophrenia pathophysiology. Although the functions of these channels are relatively well characterized by single-cell studies, the contributions of ...

    • Charting the shared genetic architecture of Alzheimer's disease, cognition, and educational attainment, and associations with brain development 

      Jaholkowski, Piotr Pawel; Bahrami, Shahram; Fominykh, Vera; Hindley, Guy; Tesfaye, Markos; Parekh, Pravesh; Parker, Nadine; Filiz, Tahir Tekin; Nordengen, Kaja; Hagen, Espen; Koch, Elise; Bakken, Nora Refsum; Frei, Evgeniia; Birkenæs, Viktoria; Rahman, Mohammad Zillur; Frei, Oleksandr; Haavik, Jan; Djurovic, Srdjan; Dale, Anders; Smeland, Olav Bjerkehagen; OConnell, Kevin Sean; Shadrin, Alexey; Andreassen, Ole A. (Journal article; Peer reviewed, 2024)
      The observation that the risk of developing Alzheimer's disease is reduced in individuals with high premorbid cognitive functioning, higher educational attainment, and occupational status has led to the ‘cognitive reserve’ ...

    • Dissecting the Shared Genetic Architecture of Common Epilepsies With Cortical Brain Morphology 

      Karadag, Naz; Hagen, Espen; Shadrin, Alexey; van der Meer, Dennis; O'Connell, Kevin Sean; Rahman, Mohammad Zillur; Kutrolli, Gleda; Parker, Nadine; Bahrami, Shahram; Fominykh, Vera; Heuser, Kjell; Taubøll, Erik; Steen, Nils Eiel; Djurovic, Srdjan; Dale, Anders M; Frei, Oleksandr; Andreassen, Ole A.; Smeland, Olav Bjerkehagen (Journal article; Peer reviewed, 2024)
      Background and Objectives: Epilepsies are associated with differences in cortical thickness (TH) and surface area (SA). However, the mechanisms underlying these relationships remain elusive. We investigated the extent to ...

    • Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression 

      Holen, Børge; Shadrin, Alexey; Icick, Romain; Filiz, Tahir Tekin; Hindley, Guy Frederick Lanyon; Rødevand, Linn; O'Connell, Kevin Sean; Hagen, Espen; Frei, Oleksandr; Bahrami, Shahram; Cheng, Weiqiu; Parker, Nadine; Woldeyohannes, Markos Tesfaye; Jaholkowski, Piotr Pawel; Karadag, Naz; Dale, Anders M; Djurovic, Srdjan; Smeland, Olav Bjerkehagen; Andreassen, Ole (Journal article; Peer reviewed, 2023)
      Opioid use disorder (OUD) and mental disorders are often comorbid, with increased morbidity and mortality. The causes underlying this relationship are poorly understood. Although these conditions are highly heritable, their ...

    • Unraveling the shared genetics of common epilepsies and general cognitive ability 

      Karadag, Naz; Hagen, Espen; Shadrin, Alexey; van der Meer, Dennis; O'Connell, Kevin Sean; Rahman, Mohammad Zillur; Kutrolli, Gleda; Parker, Nadine; Bahrami, Shahram; Fominykh, Vera; Heuser, Kjell; Taubøll, Erik; Ueland, Torill; Steen, Nils Eiel; Djurovic, Srdjan; Dale, Anders M; Frei, Oleksandr; Andreassen, Ole A.; Smeland, Olav Bjerkehagen (Journal article; Peer reviewed, 2024)
      Purpose Cognitive impairment is prevalent among individuals with epilepsy, and increasing evidence indicates that genetic factors can underlie this relationship. However, the extent to which epilepsy subtypes differ in ...