• Dwarfism in mice lacking collagen-binding integrins alpha 2 beta 1 and alpha 11 beta 1 is caused by severely diminished IGF-1 levels 

      Blumbach, Katrin; Niehoff, Anja; Belgardt, Bengt F.; Ehlen, Harald W.A.; Schmitz, Markus; Hallinger, Ralf; Schulz, Jan-Niklas; Brüning, Jens C.; Krieg, Thomas; Schubert, Markus; Gullberg, Donald; Eckes, Beate (Peer reviewed; Journal article, 2012-02)
      Mice with a combined deficiency in the α2β1 and α11β1 integrins lack the major receptors for collagen I. These mutants are born with inconspicuous differences in size but develop dwarfism within the first 4 weeks of life. ...
    • Reduced Granulation Tissue and Wound Strength in the Absence of α11β1 Integrin 

      Schulz, Jan-Niklas; Zeltz, Cedric; Sørensen, Ida Wiig; Barczyk, Malgorzata; Carracedo, Sergio; Hallinger, Ralf; Niehoff, Anja; Eckes, Beate; Gullberg, Donald (Peer reviewed; Journal article, 2015-12-08)
      Previous wound healing studies have failed to define a role for either α1β1 or α2β1 integrin in fibroblast-mediated wound contraction, suggesting the involvement of another collagen receptor in this process. Our previous ...