Blar i Bergen Open Research Archive på forfatter "Hammarsten, Ola"
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Analytical considerations in deriving 99th percentile upper reference limits for high-sensitivity cardiac troponin assays: Educational recommendations from the IFCC committee on clinical application of cardiac bio-markers
Aakre, Kristin Moberg; Saenger, Amy K.; Body, Rick; Collinson, Paul; Hammarsten, Ola; Jaffe, Allan S.; Kavsak, Pete; Omland, Torbjørn; Ordonez-Lianos, Jordi; Apple, Fred S. (Journal article; Peer reviewed, 2022)The International Federation of Clinical Chemistry Committee on Clinical Application of Cardiac Bio-Markers provides evidence-based educational documents to facilitate uniform interpretation and utilization of cardiac ... -
Antibody-mediated interferences affecting cardiac troponin assays: recommendations from the IFCC Committee on Clinical Applications of Cardiac Biomarkers
Hammarsten, Ola; Warner, Janet V.; Lam, Leo; Kavsak, Peter; Lindahl, Bertil; Aakre, Kristin Moberg; Collinson, Paul; Jaffe, Allan S.; Saenger, Amy K.; Body, Richard; Mills, Nicholas L.; Omland, Torbjørn; Ordonez-Llanos, Jordi; Apple, Fred S. (Journal article; Peer reviewed, 2023)The International Federation of Clinical Chemistry Committee on Clinical Applications of Cardiac Biomarkers (IFCC C-CB) provides educational documents to facilitate the interpretation and use of cardiac biomarkers in ... -
Flow cytometry-based functional selection of RNA interference triggers for efficient epi-allelic analysis of therapeutic targets
Micklem, David Robert; Blø, Magnus; Bergström, Petra; Hodneland, Erlend; Tiron, Crina Elena; Høiby, Torill; Gjerdrum, Christine; Hammarsten, Ola; Lorens, James B. (Peer reviewed; Journal article, 2014-06-21)Background: The dose-response relationship is a fundamental pharmacological parameter necessary to determine therapeutic thresholds. Epi-allelic hypomorphic analysis using RNA interference (RNAi) can similarly correlate ... -
Lower Limits for Reporting High-Sensitivity Cardiac Troponin Assays and Impact of Analytical Performance on Patient Misclassification
Aakre, Kristin Moberg; Apple, Fred S.; Mills, Nicolas L.; Meex, Steven J.R.; Collinson, Paul O.; Hammarsten, Ola; Jaffe, Allan S.; Omland, Torbjørn; Sandoval, Yader; Cullen, Louise (Journal article; Peer reviewed, 2024)Background: Cardiac troponin measurements are indispensable for the diagnosis of myocardial infarction and provide useful information for long-term risk prediction of cardiovascular disease. Accelerated diagnostic pathways ... -
Novel clearance of muscle proteins by muscle cells
Muslimovic, Aida; Friden, Vincent; Starnberg, Karin; Tenstad, Olav; Espedal, Heidi; Vukusic, Kristina; Nyström, Susanne; Wesén, Emelie; Esbjörner, Elin K; Granholm, Kristoffer; Lindahl, Bertil; Hammarsten, Ola (Journal article; Peer reviewed, 2020)Blood levels of cardiac troponins (cTn) and myoglobin are analysed when myocardial infarction (MI) is suspected. Here we describe a novel clearance mechanism for muscle proteins by muscle cells. The complete plasma clearance ...