Blar i Bergen Open Research Archive på forfatter "Harju, Mikael"
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Concentrations and endocrine disruptive potential of phthalates in marine mammals from the Norwegian Arctic
Routti, Heli Anna Irmeli; Harju, Mikael; Lühmann, Katharina; Aars, Jon; Ask, Amalie; Goksøyr, Anders; Kovacs, Kit M.; Lydersen, Christian (Journal article; Peer reviewed, 2021)This study investigated concentrations of phthalates (diesters of phthalic acids) in blubber/adipose tissue of blue whales (Balaenoptera musculus), fin whales (Balaenoptera physalus), bowhead whales (Balaena mysticetus) ... -
Environmental contaminants modulate the transcriptional activity of polar bear (Ursus maritimus) and human peroxisome proliferator-activated receptor alpha (PPARA)
Routti, Heli Anna Irmeli; Berg, Mari Katrine; Lille-Langøy, Roger; Øygarden, Lene Eidsvik; Harju, Mikael; Dietz, Rune; Sonne, Christian; Goksøyr, Anders (Peer reviewed; Journal article, 2019-05-06)Peroxisome proliferator-activated receptor alfa (PPARA/NR1C1) is a ligand activated nuclear receptor that is a key regulator of lipid metabolism in tissues with high fatty acid catabolism such as the liver. Here, we cloned ... -
Establishment of killer whale (Orcinus orca) primary fibroblast cell cultures and their transcriptomic responses to pollutant exposure
Bjørneset, Juni; Blévin, Pierre; Bjørnstad, Pål Marius; Dalmo, Roy Ambli; Goksøyr, Anders; Harju, Mikael; Yadetie, Fekadu; Routti, Heli Anna Irmeli (Journal article; Peer reviewed, 2023)Populations of killer whale (Orcinus orca) contain some of the most polluted animals on Earth. Yet, the knowledge on effects of chemical pollutants is limited in this species. Cell cultures and in vitro exposure experiments ...