Blar i Bergen Open Research Archive på forfatter "Hatlebakk, Jan G"
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Amelioration of Severe TNBS Induced Colitis by Novel AP-1 and NF-κB Inhibitors in Rats
El-Salhy, Magdy; Umezawa, Kazuo; Gilja, Odd Helge; Hatlebakk, Jan G; Gundersen, Doris Irene; Hausken, Trygve (Peer reviewed; Journal article, 2014-01-30)AP-1 and NF-κB inhibitors, namely, DTCM-G and DHMEQ, were investigated in male Wistar rats with severe colitis, induced by TNBS. The animals were randomized into 3 groups. The control group received 0.5 mL of 0.5% of the ... -
Densities of rectal peptide YY and somatostatin cells as biomarkers for the diagnosis of irritable bowel syndrome
El-Salhy, Magdy; Hatlebakk, Jan G; Gilja, Odd Helge; Hausken, Trygve (Peer reviewed; Journal article, 2015-03-09)Irritable bowel syndrome (IBS) is a common chronic disorder. IBS diagnosis is a diagnosis of exclusion since there are no blood tests, radiological or endoscopic examinations for this disorder. Although several attempts ... -
Duodenal Chromogranin A Cell Density as a Biomarker for the Diagnosis of Irritable Bowel Syndrome
El-Salhy, Magdy; Gilja, Odd Helge; Gundersen, Doris Irene; Hatlebakk, Jan G; Hausken, Trygve (Peer reviewed; Journal article, 2014-06-16)Background and Aim. Chromogranin A (CgA) is a common marker for endocrine cells. The density of duodenal CgA cells is reduced in patients with irritable bowel syndrome (IBS). Methods. The present study was undertaken to ... -
Endocrine cells in the ileum of patients with irritable bowel syndrome
El-Salhy, Magdy; Gilja, Odd Helge; Gundersen, Doris Irene; Hatlebakk, Jan G; Hausken, Trygve (Peer reviewed; Journal article, 2014-03-07)AIM: To study the ileal endocrine cell types in irritable bowel syndrome (IBS) patients. METHODS: Ninety-eight patients with IBS (77 females and 21 males; mean age 35 years, range 18-66 years) were included, of which 35 ... -
Interaction between ingested nutrients and gut endocrine cells in patients with irritable bowel syndrome (Review)
El-Salhy, Magdy; Gilja, Odd Helge; Gundersen, Doris Irene; Hatlebakk, Jan G; Hausken, Trygve (Peer reviewed; Journal article, 2014-08)Several endocrine cell abnormalities have been reported in different segments of the gastrointestinal tract of patients with irritable bowel syndrome (IBS). These cells have specialized microvilli that project into the ... -
Is irritable bowel syndrome an organic disorder?
El-Salhy, Magdy; Gundersen, Doris Irene; Gilja, Odd Helge; Hatlebakk, Jan G; Hausken, Trygve (Peer reviewed; Journal article, 2014-01-14)Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that is generally considered to be functional because there appears to be no associated anatomical defect. Stress and psychological factors are thought ... -
Stomach antral endocrine cells in patients with irritable bowel syndrome
El-Salhy, Magdy; Gilja, Odd Helge; Hatlebakk, Jan G; Hausken, Trygve (Peer reviewed; Journal article, 2014-10)To the best of our knowledge, stomach antral endocrine cells have not previously been investigated in patients with irritable bowel syndrome (IBS). Thus, in the present study, 76 patients with IBS were examined (designated ...