Blar i Bergen Open Research Archive på forfatter "Haugen, Mette"

Viser treff 1-8 av 8

    • Case report: Pain in anti-DPPX encephalitis 

      Bjerknes, Tale Litlere; Steihaug, Ole Martin; Haugen, Mette; Hjelland, Ina Elen; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2022)
      Encephalitis due to antibodies targeting dipeptidyl-peptidase-like protein 6 (DPPX), a potassium channel subunit, is rare. The illness is typically characterized by a triad of weight loss, CNS hyperexcitability and cognitive ...

    • Case report: Seropositive myasthenia gravis complicated by limbic encephalitis positive for antibodies to AMPAR and Lgi1 

      Nes, Magne Solberg; Haugen, Mette; Haugland, Hans Kristian; Gilhus, Nils Erik; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2023-10-12)
      Objectives: Autoantibodies to the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) and leucine-rich glioma-inactivated 1 (Lgi1) are associated with autoimmune encephalitis. We described an acetylcholine ...

    • CDR2 antigen and Yo antibodies 

      Totland, Cecilie; Aarskog, Nina K.; Eichler, Tilo W.; Haugen, Mette; Nøstbakken, Jane K.; Monstad, Sissel E.; Salvesen, Helga Birgitte; Mørk, Sverre; Haukanes, Bjørn Ivar; Vedeler, Christian A. (Peer reviewed; Journal article, 2011)
      Paraneoplastic cerebellar degeneration (PCD) is often associated with Yo antibodies that are directed against human cerebellar degeneration-related protein 2 (CDR2). Such antibodies may also be found in ovarian cancer ...

    • CDR2L Is the Major Yo Antibody Target in Paraneoplastic Cerebellar Degeneration 

      Kråkenes, Torbjørn; Herdlevær, Ida Ajvazi; Raspotnig, Margrethe; Haugen, Mette; Schubert, Manja; Vedeler, Christian A. (Peer reviewed; Journal article, 2019)
      The pathogenesis of Yo‐mediated paraneoplastic cerebellar degeneration (PCD) is unclear. We applied cerebrospinal fluid and serum from PCD patients as well as CDR2 and CDR2L antibodies to neuronal tissue, cancer cell lines, ...

    • A cerebellar degeneration-related protein 2-like cell-based assay for anti-Yo detection in patients with paraneoplastic cerebellar degeneration 

      Erikstad, Kjell Inge; Herdlevær, Ida Ajvazi; Peter, Elise Marie; Haugen, Mette; Totland, Cecilie; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2023)
      Background and purpose Commercially available tests for Yo antibody detection have low specificity for paraneoplastic cerebellar degeneration (PCD) because these assays use cerebellar degeneration-related protein 2 (CDR2) ...

    • CRMP5 Antibodies—Diagnostic Challenges 

      Totland, Cecilie; Haugen, Mette; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2021-09-22)
      CRMP5-associated paraneoplastic neurological syndromes (PNS) are rare, and only few studies describe larger cohorts of patients with CRMP5 antibodies. We have included 24 patients with CRMP5 antibodies and compared clinical ...

    • Paraneoplastic CDR2 and CDR2L antibodies affect Purkinje cell calcium homeostasis 

      Schubert, Manja; Panja, Debabrata; Haugen, Mette; Bramham, Clive R.; Vedeler, Christian A. (Peer reviewed; Journal article, 2014-12)
      Paraneoplastic cerebellar degeneration (PCD) is characterized by loss of Purkinje cells (PCs) associated with progressive pancerebellar dysfunction in the presence of onconeural Yo antibodies. These antibodies recognize ...

    • Progressive striatal necrosis associated with anti-NMDA receptor antibodies 

      Tzoulis, Charalampos; Vedeler, Christian A.; Haugen, Mette; Storstein, Anette; Tran, Gia Tuong Thi; Gjerde, Ivar Otto; Biermann, Martin; Schwarzlmüller, Thomas; Bindoff, Laurence (Peer reviewed; Journal article, 2013-05-31)
      Background: We report a case of childhood onset, generalized dystonia due to slowly progressive bilateral striatal necrosis associated with anti-N-methyl-D-aspartate receptor (NMDAR) antibodies. This clinical phenotype has ...