Blar i Bergen Open Research Archive på forfatter "Haugland, Gyri Teien"
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Antibiotic uptake by cultured Atlantic cod leucocytes and effect on intracellular Francisella noatunensis subsp. noatunensis replication
Kaldestad, Marte Albriktsen; Haugland, Gyri Teien; Rønneseth, Anita; Wergeland, Heidrun Inger; Samuelsen, Ole Bent (Peer reviewed; Journal article, 2014-02-04)The granuloma disease caused by Francisella noatunensis subsp. noatunensis in farmed Atlantic cod has not been successfully treated by use of antibacterials, even when antibacterial resistance testing indicates a sufficient ... -
Characterization of Small, Mononuclear Blood Cells from Salmon Having High Phagocytic Capacity and Ability to Differentiate into Dendritic like Cells
Haugland, Gyri Teien; Jordal, Ann-Elise Olderbakk; Wergeland, Heidrun Inger (Peer reviewed; Journal article, 2012-11-14)Phagocytes are the principal component of the innate immune system, playing a key role in the clearance of foreign particles that include potential pathogens. In vertebrates, both neutrophils and mononuclear cells like ... -
Development of anaesthetic protocols for lumpfish (Cyclopterus lumpus L.): Effect of anaesthetic concentrations, sea water temperature and body weight
Skår, Malene W.; Haugland, Gyri Teien; Powell, Mark; Wergeland, Heidrun Inger; Samuelsen, Ole Bent (Peer reviewed; Journal article, 2017-07-05)In recent years, use of lumpfish (Cyclopterus lumpus L.) as cleaner-fish to remove sea-lice have been chosen by many salmon farmers in Europe and Canada as an alternative to medical treatment, which has led to large scale ... -
The Escherichia coli alkA Gene Is Activated to Alleviate Mutagenesis by an Oxidized Deoxynucleoside
Grøsvik, Kristin; Tesfahun, Almaz Nigatu; Muruzábal-Lecumberri, Izaskun; Haugland, Gyri Teien; Leiros, Ingar; Ruoff, Peter; Kvaløy, Jan Terje; Knævelsrud, Ingeborg; Ånensen, Hilde; Alexeeva, Marina; Sato, Kousuke; Matsuda, Akira; Alseth, Ingrun; Klungland, Arne; Bjelland, Svein (Journal article; Peer reviewed, 2020)The cellular methyl donor S-adenosylmethionine (SAM) and other endo/exogenous agents methylate DNA bases non-enzymatically into products interfering with replication and transcription. An important product is 3-methyladenine ... -
Interleukin-1 ligands and receptors in lumpfish (Cyclopterus lumpus L.): molecular characterization, phylogeny, gene expression and transcriptome analyses
Eggestøl, Håvard Øritsland; Lunde, Harald Sæbø; Knutsen, Tim Martin; Haugland, Gyri Teien (Journal article; Peer reviewed, 2020-04-02)The interleukin (IL)-1 family play a fundamental role as immune system modulators. Our previous transcriptome-analyses of leukocytes from lumpfish (Cyclopterus lumpus L.) showed that IL-1β was among the most highly upregulated ... -
Phagocytosis and Respiratory Burst Activity in Lumpsucker (Cyclopterus lumpus L.) Leucocytes Analysed by Flow Cytometry
Haugland, Gyri Teien; Jakobsen, Ragnhild Aakre; Vestvik, Nils; Ulven, Kristian; Stokka, Lene; Wergeland, Heidrun Inger (Peer reviewed; Journal article, 2012-10-24)In the present study, we have isolated leucocytes from peripheral blood, head kidney and spleen from lumpsucker (Cyclopterus lumpus L.), and performed functional studies like phagocytosis and respiratory burst, as well as ... -
Pharmacokinetic Data Show That Oxolinic Acid and Flumequine Are Absorbed and Excreted Rapidly From Plasma and Tissues of Lumpfish
Haugland, Gyri Teien; Kverme, Karen obrestad; Hannisdal, Rita; Kallekleiv, Marielle; Colquhoun, Duncan John; Lunestad, Bjørn Tore; Wergeland, Heidrun Inger; Samuelsen, Ole Bent (Peer reviewed; Journal article, 2019-11-12)This study examined the uptake, tissue distribution and elimination of the antibacterial agents oxolinic acid and flumequine in lumpfish (Cyclopterus lumpus L.) by use of LC-MS/MS following a single oral administration of ... -
Pharmacokinetics of florfenicol in lumpfish (Cyclopterus lumpus L.) after a single oral administration
Kverme, Karen Obrestad; Haugland, Gyri Teien; Hannisdal, Rita; Kallekleiv, Marielle; Colquhoun, Duncan John; Lunestad, Bjørn Tore; Wergeland, Heidrun Inger; Samuelsen, Ole Bent (Peer reviewed; Journal article, 2019)Farming of lumpfish for biological removal of sea lice from farmed Atlantic salmon has expanded rapidly in Europe and Canada over the last 5–6 years and the lumpfish has become an economically important species. There are, ... -
The proinflammatory cytokines TNF-α and IL-6 in lumpfish (Cyclopterus lumpus L.) -identification, molecular characterization, phylogeny and gene expression analyses
Eggestøl, Håvard Øritsland; Haugland, Gyri Teien; Lunde, Harald S. (Journal article; Peer reviewed, 2020)The proinflammatory cytokines TNF-α and IL-6 are important mediators of inflammatory reactions and orchestrators of the immune system in vertebrate. In this study, we have identified TNF-α and IL-6 in lumpfish, molecular ... -
Stimulation of MCM helicase activity by a Cdc6 protein in the archaeon Thermoplasma acidophilum
Haugland, Gyri Teien; Shin, J.H.; Birkeland, Nils-Kåre; Kelman, Z. (Peer reviewed; Journal article, 2006-11-15)Replicative DNA helicases are ring-shaped hexamers that play an essential role in chromosomal DNA replication. They unwind the two strands of the duplex DNA and provide the single-stranded (ss) DNA substrate for the ... -
Thermoplasma acidophilum Cdc6 protein stimulates MCM helicase activity by regulating its ATPase activity
Haugland, Gyri Teien; Sakakibara, N; Pey, Angel; Rollor, Clair R; Birkeland, Nils-Kåre; Kelman, Zvi (Peer reviewed; Journal article, 2008-08-30)The minichromosome maintenance (MCM) proteins are thought to function as the replicative helicases in archaea. In most archaeal species studied, the interaction between MCM and the initiator protein, Cdc6, inhibits helicase ...