Blar i Bergen Open Research Archive på forfatter "Hausen, Harald"
-
Comparative analysis defines a broader FMRFamide-gated sodium channel family and determinants of neuropeptide sensitivity
Dandamudi, Mowgli; Hausen, Harald; Lynagh, Timothy Peter (Journal article; Peer reviewed, 2022)FMRFamide (Phe-Met-Arg-Phe-amide, FMRFa) and similar neuropeptides are important physiological modulators in most invertebrates, but the molecular basis of FMRFa activity at its receptors is unknown. We therefore sought ... -
The development of early pioneer neurons in the annelid Malacoceros fuliginosus
Hausen, Harald; Kumar, Suman; Tumu, Sharat Chandra; Helm, Conrad (Journal article; Peer reviewed, 2020)Background Nervous system development is an interplay of many processes: the formation of individual neurons, which depends on whole-body and local patterning processes, and the coordinated growth of neurites and synapse ... -
Early evolution of radial glial cells in Bilateria
Helm, Conrad; Karl, Anett; Beckers, Patrick; Kaul-Strehlow, Sabrina; Ulbricht, Elke; Kourtesis, Ioannis; Kuhrt, Heidrun; Hausen, Harald; Bartolomaeus, Thomas; Reichenbach, Andreas; Bleidorn, Christoph (Journal article; Peer reviewed, 2017)Bilaterians usually possess a central nervous system, composed of neurons and supportive cells called glial cells. Whereas neuronal cells are highly comparable in all these animals, glial cells apparently differ, and in ... -
Owenia fusiformis – a basally branching annelid suitable for studying ancestral features of annelid neural development
Helm, Conrad; Vöcking, Oliver; Kourtesis, Ioannis; Hausen, Harald (Journal article; Peer reviewed, 2016-06-16)Background Comparative investigations on bilaterian neurogenesis shed light on conserved developmental mechanisms across taxa. With respect to annelids, most studies focus on taxa deeply nested within the annelid tree, ... -
Posterior eyespots in larval chitons have a molecular identity similar to anterior cerebral eyes in other bilaterians
Hausen, Harald; Vöcking, Oliver; Kourtesis, Ioannis (Journal article; Peer reviewed, 2015-12-22)Background: Development of cerebral eyes is generally based on fine-tuned networks and closely intertwined with the formation of brain and head. Consistently and best studied in insects and vertebrates, many signaling ... -
The rhodopsin-retinochrome system for retinal re-isomerization predates the origin of cephalopod eyes
Vöcking, Oliver; Leclère, Lucas; Hausen, Harald (Journal article; Peer reviewed, 2021-11-29)Background: The process of photoreception in most animals depends on the light induced isomerization of the chromophore retinal, bound to rhodopsin. To re-use retinal, the all-trans-retinal form needs to be re-isomerized ... -
The visual pigment xenopsin is widespread in protostome eyes and impacts the view on eye evolution
Hausen, Harald; Döring, Clemens; Kumar, Suman; Tumu, Sharat Chandra; Kourtesis, Ioannis (Journal article; Peer reviewed, 2020)Photoreceptor cells in the eyes of Bilateria are often classified into microvillar cells with rhabdomeric opsin and ciliary cells with ciliary opsin, each type having specialized molecular components and physiology. First ...