Blar i Bergen Open Research Archive på forfatter "Hegvik, Tor-Arne"
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Associations between attention-deficit/hyperactivity disorder and autoimmune diseases are modified by sex: a population-based cross-sectional study
Hegvik, Tor-Arne; Instanes, Johanne Telnes; Haavik, Jan; Klungsøyr, Kari; Engeland, Anders (Peer reviewed; Journal article, 2018-05)Several studies have demonstrated associations between neuropsychiatric disorders, such as attention-deficit/hyperactivity disorder (ADHD), and the immune system, including autoimmune diseases. Since ADHD and many autoimmune ... -
Attention-deficit/hyperactivity disorder and smoking habits in pregnant women
Anderson, Anneli; Hegvik, Tor-Arne; Chen, Qi; Kvalvik, Liv Grimstvedt; Almqvist, Catarina; D'Onofrio, Brian M.; Hartman, Catharina A; Klungsøyr, Kari; Haavik, Jan; Tuvblad, Catherine; Larsson, Henrik (Journal article; Peer reviewed, 2020)Background Attention-deficit/hyperactivity disorder (ADHD) has been associated with an increased risk of tobacco smoking, and more difficulties with smoking cessation compared to non-ADHD individuals. Women with ADHD may ... -
A candidate gene investigation of methylphenidate response in adult attention-deficit/hyperactivity disorder patients: results from a naturalistic study
Hegvik, Tor-Arne; Jacobsen, Kaya Kvarme; Fredriksen, Mats; Zayats, Tetyana; Haavik, Jan (Peer reviewed; Journal article, 2016-08)Attention-deficit/hyperactivity disorder (ADHD) is a common childhood onset neuropsychiatric disorder with a complex and heterogeneous symptomatology. Persistence of ADHD symptoms into adulthood is common. Methylphenidate ... -
Common psychiatric and metabolic comorbidity of adult attention-deficit/hyperactivity disorder: A population-based cross-sectional study
Chen, Qi; Hartman, Catharina A; Haavik, Jan; Harro, Jaanus; Klungsøyr, Kari; Hegvik, Tor-Arne; Wanders, Rob; Ottosen, Cæcilie; Dalsgaard, Søren; Faraone, Stephen V.; Larsson, Henrik (Peer reviewed; Journal article, 2018-09-26)Attention-deficit/hyperactivity disorder (ADHD) is often comorbid with other psychiatric conditions in adults. Yet, less is known about its relationship with common metabolic disorders and how sex and ageing affect the ... -
Druggable genome in attention deficit/hyperactivity disorder and its co-morbid conditions. New avenues for treatment.
Hegvik, Tor-Arne; Waløen, Kai; Pandey, Sunil Kumar; Faraone, Stephen V.; Haavik, Jan; Zayats, Tetyana (Peer reviewed; Journal article, 2019)Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder with only symptomatic care available. Genome-wide association (GWA) studies can provide a starting point in the search for novel drug ... -
GADL1 is a multifunctional decarboxylase with tissue-specific roles in β-alanine and carnosine production
Mahootchi, Elaheh; Homaei, Selina Cannon; Kleppe, Rune; Winge, Ingeborg; Hegvik, Tor-Arne; Perez, Roberto Megias; Totland, Christian; Mogavero, Floriana; Baumann, Anne; Glennon, Jeffrey Colm; Miletic, Hrvoje; Kursula, Petri; Haavik, Jan (Journal article; Peer reviewed, 2020)Carnosine and related β-alanine–containing peptides are believed to be important antioxidants, pH buffers, and neuromodulators. However, their biosynthetic routes and therapeutic potential are still being debated. This ... -
Maternal pre-pregnancy overweight/obesityand the risk of attention-deficit/hyperactivitydisorder in offspring: a systematic review, meta-analysis and quasi-experimental family-based study
Li, Lin; Lagerberg, Tyra; Chang, Zheng; Cortese, Samuele; Rosenqvist, Mina A.; Almqvist, Catarina; D'Onofrio, Brian M.; Hegvik, Tor-Arne; Hartman, Catharina A.; Chen, Qi; Larsson, Henrik (Journal article; Peer reviewed, 2020)Previous studies are inconclusive concerning the association between maternal pre-pregnancy overweight/obesity and risk of attention-deficit/hyperactivity disorder (ADHD) in offspring. We therefore conducted a systematic ... -
Paraneoplastic syndrome-associated neuronal antibodies in adult ADHD
Haukanes, Bjørn Ivar; Hegvik, Tor-Arne; Eichler, Tilo Wolf; Haavik, Jan; Vedeler, Christian A. (Peer reviewed; Journal article, 2015-09-01)A high seroprevalence of Yo antibodies targeting cerebellar Purkinje cells was recently reported in children with attention deficit/hyperactivity disorder (ADHD). We investigated the presence of 8 paraneoplastic neurological ... -
Serum concentrations of kynurenines in adult patients with attention-deficit hyperactivity disorder (ADHD): a case–control study
Hegvik, Tor-Arne; Ulvik, Arve; Halmøy, Anne; Haavik, Jan; Aarsland, Tore Ivar Malmei; Landaas, Elisabeth Toverud; Ueland, Per Magne (Peer reviewed; Journal article, 2015-11-05)Background: The essential amino acid tryptophan is catabolised mainly through the kynurenine pathway. Altered circulating levels of kynurenines have been reported in chronic inflammatory conditions and in several ... -
Sex differences in parent–offspring recurrence of attention-deficit/hyperactivity disorder
Solberg, Berit Skretting; Hegvik, Tor-Arne; Halmøy, Anne; Skjaerven, Rolv; Engeland, Anders; Haavik, Jan; Klungsøyr, Kari (Journal article; Peer reviewed, 2020)Background Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental disorder sharing genetic risk factors with other common psychiatric disorders. However, intergenerational recurrence ...